Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Edward C. Eckels"'
Autor:
Shubhasis Haldar, Rafael Tapia-Rojo, Edward C. Eckels, Jessica Valle-Orero, Julio M. Fernandez
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Proteins fold under mechanical force during co-translational folding at the ribosome. Here, the authors use single molecule magnetic tweezers to study the influence of chaperones on protein folding and show that the ribosomal chaperone trigger factor
Externí odkaz:
https://doaj.org/article/c435eaed6d044a0d845d5ba987b97fa9
Autor:
Edward C. Eckels, Shubhasis Haldar, Rafael Tapia-Rojo, Jaime Andrés Rivas-Pardo, Julio M. Fernández
Publikováno v:
Cell Reports, Vol 27, Iss 6, Pp 1836-1847.e4 (2019)
Summary: The delivery of mechanical power, a crucial component of animal motion, is constrained by the universal compromise between the force and the velocity of its constituent molecular systems. While the mechanisms of force generation have been st
Externí odkaz:
https://doaj.org/article/29d69a552a404682bf00166e52125f7d
Autor:
Jaime Andrés Rivas-Pardo, Edward C. Eckels, Ionel Popa, Pallav Kosuri, Wolfgang A. Linke, Julio M. Fernández
Publikováno v:
Cell Reports, Vol 14, Iss 6, Pp 1339-1347 (2016)
Current theories of muscle contraction propose that the power stroke of a myosin motor is the sole source of mechanical energy driving the sliding filaments of a contracting muscle. These models exclude titin, the largest protein in the human body, w
Externí odkaz:
https://doaj.org/article/6bfc5110ef5e42078ad599658364fa8a
Publikováno v:
Chemical Science
DsbA is a ubiquitous bacterial oxidoreductase that associates with substrates during and after translocation, yet its involvement in protein folding and translocation remains an open question. Here we demonstrate a redox-controlled chaperone activity
Autor:
Jessica Valle-Orero, Julio M. Fernandez, Rafael Tapia-Rojo, Edward C. Eckels, Shubhasis Haldar
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-7 (2017)
Nature Communications
Nature Communications
Proteins fold under mechanical forces in a number of biological processes, ranging from muscle contraction to co-translational folding. As force hinders the folding transition, chaperones must play a role in this scenario, although their influence on
Autor:
Daniel J. Echelman, Alvaro Alonso-Caballero, Rafael Tapia-Rojo, Shubhasis Haldar, Julio M. Fernandez, Edward C. Eckels
Publikováno v:
Nature chemistry
Gram-positive bacteria colonize mucosal tissues, withstanding large mechanical perturbations such as coughing, which generate shear forces that exceed the ability of non-covalent bonds to remain attached. To overcome these challenges, the pathogen St
Autor:
Daniel J. Echelman, Shubhasis Haldar, Julio M. Fernandez, Alvaro Alonso-Caballero, Rafael Tapia-Rojo, Edward C. Eckels
Gram positive bacteria colonize mucosal tissues against large mechanical perturbations, such as coughing, which generate large shear forces that exceed the ability of non-covalent bonds to remain attached. To overcome these challenges, the pathogen S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d3a23db6fe4d00066a0cc0f603357c
https://doi.org/10.1101/743393
https://doi.org/10.1101/743393
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(16)
Magnetic tape heads are ubiquitously used to read and record on magnetic tapes in technologies as diverse as old VHS tapes, modern hard-drive disks, or magnetic bands on credit cards. Their design highlights the ability to convert electric signals in
Autor:
Shubhasis Haldar, Jaime Andres Rivas Pardo, Rafael Tapia-Rojo, Julio M. Fernandez, Edward C. Eckels
Publikováno v:
Cell reports
Cell Reports, Vol 27, Iss 6, Pp 1836-1847.e4 (2019)
Cell Reports, Vol 27, Iss 6, Pp 1836-1847.e4 (2019)
SUMMARY The delivery of mechanical power, a crucial component of animal motion, is constrained by the universal compromise between the force and the velocity of its constituent molecular systems. While the mechanisms of force generation have been stu
Autor:
Edward C. Eckels, Pallav Kosuri, Jaime Andrés Rivas-Pardo, Wolfgang A. Linke, Ionel Popa, Julio M. Fernandez
Publikováno v:
Cell Reports, Vol 14, Iss 6, Pp 1339-1347 (2016)
SummaryCurrent theories of muscle contraction propose that the power stroke of a myosin motor is the sole source of mechanical energy driving the sliding filaments of a contracting muscle. These models exclude titin, the largest protein in the human