Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Edward C Goodwin"'
Autor:
Andreea Popa, Wei Zhang, Megan S Harrison, Kylia Goodner, Teymur Kazakov, Edward C Goodwin, Alex Lipovsky, Christopher G Burd, Daniel DiMaio
Publikováno v:
PLoS Pathogens, Vol 11, Iss 2, p e1004699 (2015)
Trafficking of human papillomaviruses to the Golgi apparatus during virus entry requires retromer, an endosomal coat protein complex that mediates the vesicular transport of cellular transmembrane proteins from the endosome to the Golgi apparatus or
Externí odkaz:
https://doaj.org/article/12466746ba26441aa75b0150a96e588c
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e94322 (2014)
DNAJB12 and DNAJB14 are transmembrane proteins in the endoplasmic reticulum (ER) that serve as co-chaperones for Hsc70/Hsp70 heat shock proteins. We demonstrate that over-expression of DNAJB12 or DNAJB14 causes the formation of elaborate membranous s
Externí odkaz:
https://doaj.org/article/3512251516924d04817abd64e9aa3892
Autor:
Marcia V. Fournier, Adam Brufsky, Joan Chen, Susan Tannenbaum, John C. Obenauer, Edward C. Goodwin
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-9 (2019)
Scientific Reports
Scientific Reports
We developed a test to predict which patients will achieve pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) and which will have residual disease (RD). Gene expression data from pretreatment biopsies of patients with all breast c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41a599d5de29981d153cdd7a7997c8fe
http://link.springer.com/article/10.1038/s41598-019-51335-1
http://link.springer.com/article/10.1038/s41598-019-51335-1
Autor:
Marcia V. Fournier, Adam Brufsky, Joan Chen, Susan Tannenbaum, John C. Obenauer, Edward C. Goodwin
Publikováno v:
Cancer Research. 78:P2-10
Prediction of pathological complete response (pCR) for neoadjuvant treatment is an area of unmet clinical need, especially for triple negative breast cancer (TNBC) as pCR is correlated with better outcomes. Predicting which patients will have residua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb8becc092f21fe4a3c139c577349f47
https://doi.org/10.1158/1538-7445.sabcs17-p2-10-08
https://doi.org/10.1158/1538-7445.sabcs17-p2-10-08
Autor:
Edward C. Goodwin, Alex Lipovsky, Takamasa Inoue, Thomas G. Magaldi, Anne P. B. Edwards, Kristin E. Y. Van Goor, Adrienne W. Paton, James C. Paton, Walter J. Atwood, Billy Tsai, Daniel DiMaio
Publikováno v:
mBio, Vol 2, Iss 3 (2011)
ABSTRACT Simian virus 40 (SV40) is a nonenveloped DNA virus that traffics through the endoplasmic reticulum (ER) en route to the nucleus, but the mechanisms of capsid disassembly and ER exit are poorly understood. We conducted an unbiased RNA interfe
Externí odkaz:
https://doaj.org/article/7d5ff50acbcd43f9ac63ba8b338523b9
Autor:
Lucas Delmonico, Said Attiya, Joan W Chen, John C. Obenauer, Edward C. Goodwin, Marcia V. Fournier
Publikováno v:
Disease Markers
Disease Markers, Vol 2019 (2019)
Disease Markers, Vol 2019 (2019)
Background. With the development of new drug combinations and targeted treatments for multiple types of cancer, the ability to stratify categories of patient populations and to develop companion diagnostics has become increasingly important. A panel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf5fa06ee4c977dc97d673a54daafb60
Publikováno v:
Virology. 444:257-262
High-risk human papillomaviruses (HPVs) cause a variety of malignancies of the mucosal epithelium. However, the local immune evasion strategies used by HPV-transformed cells remain unclear. Here, we examined the effect of HPV-positive cancer cells on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ada7cd86e9eb22a0cc2eba26520a4a52
https://doi.org/10.1016/j.virol.2013.06.020
https://doi.org/10.1016/j.virol.2013.06.020
Publikováno v:
Cancer Research. 78:5576-5576
Screening and prevention is critical to reducing breast cancer deaths, and mammography is not an ideal tool. Mammography has not reduced invasive breast cancer incidence, it has high numbers of false positives and it detects many non-invasive cancers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2a6104b4972fca4b2fc2c60557e8604d
https://doi.org/10.1158/1538-7445.am2018-5576
https://doi.org/10.1158/1538-7445.am2018-5576
Publikováno v:
Cancer Research. 78:LB-217
From over two hundred driver mutations identified to date, only about a dozen are FDA-approved biomarkers, and there is an unmet need to discover novel suitable biomarkers. We selected novel biomarkers based on non-malignant breast epithelial cell ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::32ccaca36576e5d12959cf7c34e0f524
https://doi.org/10.1158/1538-7445.am2018-lb-217
https://doi.org/10.1158/1538-7445.am2018-lb-217
Publikováno v:
Journal of Virology. 83:5630-5639
We developed a high-throughput, cell-based screen to identify chemicals that inhibit infection by the primate polyomaviruses. The screen is based on the detection of compounds that inhibit the ability of a replication-defective simian virus 40 (SV40)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4438e1d9a7fa7133641ea55b3a287a0a
https://doi.org/10.1128/jvi.00203-09
https://doi.org/10.1128/jvi.00203-09