Zobrazeno 1 - 10 of 172 pro vyhledávání: '"Edward Bresnick"'
1
Distinct roles for p53 transactivation and repression in preventing UCN-01-mediated abrogation of DNA damage-induced arrest at S and G2 cell cycle checkpoints
Autor: Aime A. Levesque, Alan Eastman, Edward Bresnick, Ethan A. Kohn
Publikováno v: Oncogene. 24:3786-3796
The topoisomerase I inhibitor SN38 arrests cell cycle progression primarily in S or G(2) phases of the cell cycle in a p53-independent manner. The Chk1 inhibitor, 7-hydroxystaurosporine (UCN-01), overcomes both S and G(2) arrest preferentially in cel
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24dfa6a7fb0a89ca653a9c3cc06b773f
https://doi.org/10.1038/sj.onc.1208451
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2
Positive and negative regulation of ΔN-p63 promoter activity by p53 and ΔN-p63-α contributes to differential regulation of p53 target genes
Autor: Kelly E Heim, James DiRenzo, Julie Watson, David Christopher Harmes, Emma A Lubin, Edward Bresnick, Justin Lamb, Anne M Suskind, Joshua C. Curtin
Publikováno v: Oncogene. 22:7607-7616
Mammary epithelial regeneration implies the existence of cellular progenitors with retained replicative capacity, prolonged lifespan and developmental potency. Evidence exists that deltaN-p63 isoforms preserve these features by modulating p53 activit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4661f56bd93817ac56d1519867dae3c
https://doi.org/10.1038/sj.onc.1207129
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3
Glycine N-Methyltransferase Is an Example of Functional Diversity
Autor: Edward Bresnick, Rashid Bhat
Publikováno v: Journal of Biological Chemistry. 272:21221-21226
The cytochrome P-4501A1 (CYP1A1) gene is regulated by several trans-acting factors including the 4 S polycyclic aromatic hydrocarbon (PAH)-binding protein, which has recently been identified as glycine N-methyltransferase (GNMT) (Raha, A., Wagner, C.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee34ef6aac5f63c906c32135a26d4ae4
https://doi.org/10.1074/jbc.272.34.21221
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4
The Homodimeric Form of Glycine N-Methyltransferase Acts as a Polycyclic Aromatic Hydrocarbon-Binding Receptor
Autor: Edward Bresnick, Rashid Bhat, Conrad Wagner
Publikováno v: Biochemistry. 36:9906-9910
In the rat, cytochrome P4501A1 gene expression is thought to be regulated by several trans-acting factors including the 4S polycyclic aromatic hydrocarbon (PAH)-binding protein, which was recently identified as glycine N-methyltransferase [Raha, A.,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bafc99e6cca2e875abcaf104925e762a
https://doi.org/10.1021/bi970159x
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5
ATP Depletion Affects the Phosphorylation State, Ligand Binding, and Nuclear Transport of the 4 S Polycyclic Aromatic Hydrocarbon-binding Protein in Rat Hepatoma Cells
Autor: Edward Bresnick, Rashid Bhat, James A. Weaver, Conrad Wagner, Jack E. Bodwell
Publikováno v: Journal of Biological Chemistry. 271:32551-32556
In the rat, cytochrome P4501A1 gene expression is thought to be regulated by several trans-acting factors including the 4 S polycyclic aromatic hydrocarbon (PAH)-binding protein. Phosphorylation and dephosphorylation have been suggested to influence
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df154e6e3ede025cb86d28f0cc09c084
https://doi.org/10.1074/jbc.271.51.32551
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6
Nuclear transcription factor Oct-1 binds to the 5′-upstream region of CYP1A1 and negatively regulates its expression
Autor: Edward Bresnick, J. A. Weaver, Rashid Bhat, K. M. Sterling
Publikováno v: The International Journal of Biochemistry & Cell Biology. 28:217-227
The cytochrome P450-dependent monooxygenases, which represent an extended superfamily, catalyze the biotransformation of many endogenous and exogenous substances. One of these hemoproteins, cytochrome P4501A1, is most closely associated with the bioa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80dd9ea02db22dd8019574bb1a1e67cc
https://doi.org/10.1016/1357-2725(95)00122-0
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7
Glycine N-Methyltransferase Is a Mediator of Cytochrome P4501A1 Gene Expression
Autor: S. Gusky, T. Joyce, Edward Bresnick, Abhijit Raha
Publikováno v: Archives of Biochemistry and Biophysics. 322:395-404
Cytochrome P4501A1, the isozyme most closely approximating aryl hydrocarbon hydroxylase activity under conditions of induction, is thought to be regulated by several trans-acting factors, including the 4S polycyclic aromatic hydrocarbon-binding prote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f9958dd28f44547184369ba4c45cdc3
https://doi.org/10.1006/abbi.1995.1480
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8
Induction of CYP1A1 Gene Expression in Mouse Hepatoma Cells by Benzo(e)Pyrene, a Ligand of the 4S Polycyclic Hydrocarbon-Binding Protein
Autor: K. Sterling, Abhijit Raha, Edward Bresnick
Publikováno v: Toxicology and Applied Pharmacology. 128:18-24
Hepa 1c1c7 (WT), TAOc1BPrc1 (CI), and BPrc1 (CII) mouse hepatoma cells were exposed to benzo[e]pyrene (B[e]P) or benzo[a]pyrene (B[a]P). B[e]P induced activity of a rat CYP1A1 reporter gene construct (-3015 to +2545 bp) by 1.8- to 2-fold and 5-fold i
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6d57078470c3b383917c23a963e13c6
https://doi.org/10.1006/taap.1994.1175
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10
Rat liver cytosolic 4 S polycyclic aromatic hydrocarbon-binding protein is glycine N-methyltransferase
Autor: Edward Bresnick, Conrad Wagner, Abhijit Raha, Richard G. MacDonald
Publikováno v: Journal of Biological Chemistry. 269:5750-5756
In the rat, cytochrome P-450IA1 gene expression, which is most closely associated with aryl hydrocarbon hydroxylase activity, is thought to be regulated by several trans-acting factors, including the 4 S polycyclic aromatic hydrocarbon (PAH)-binding
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a50ee5eee090375505a460c689303b8
https://doi.org/10.1016/s0021-9258(17)37525-7
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