Výsledky vyhledávání - "Edward B Prideaux"

Akademický článek

Joint-specific regulation of homeobox D10 expression in rheumatoid arthritis fibroblast-like synoviocytes.

Autor: Hyeonjeong Lee, Camilla R L Machado, Deepa Hammaker, Eunice Choi, Edward B Prideaux, Wei Wang, David L Boyle, Gary S Firestein

Publikováno v: PLoS ONE, Vol 19, Iss 6, p e0304530 (2024)

Rheumatoid arthritis (RA) is a systemic immune-mediated disease characterized by joint inflammation and destruction. The disease typically affects small joints in the hands and feet, later progressing to involve larger joints such as the knees, shoul

Externí odkaz: https://doaj.org/article/2b85a7c05bcd4e318c6f0ff23d6ac2bb

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Akademický článek

Caspase‐8 Variant G Regulates Rheumatoid Arthritis Fibroblast‐Like Synoviocyte Aggressive Behavior

Autor: Cecilia Ansalone, Richard I. Ainsworth, Gyrid Nygaard, Rizi Ai, Edward B. Prideaux, Deepa Hammaker, Narayanan B. Perumal, Ken Weichert, Frances Tung, Lalitha Kodandapani, J. Michael Sauder, Elisabeth C. Mertsching, Robert J. Benschop, David L. Boyle, Wei Wang, Gary S. Firestein

Publikováno v: ACR Open Rheumatology, Vol 4, Iss 4, Pp 288-299 (2022)

Objective Fibroblast‐like synoviocytes (FLS) play a pivotal role in rheumatoid arthritis (RA) by contributing to synovial inflammation and progressive joint damage. An imprinted epigenetic state is associated with the FLS aggressive phenotype. We i

Externí odkaz: https://doaj.org/article/7bf9364f9ed048b68c6e9061d4e747da

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Akademický článek

Improving Transcriptome Fidelity Following Synovial Tissue Disaggregation

Autor: David L. Boyle, Edward B. Prideaux, Joshua Hillman, Wei Wang, Gary S. Firestein

Publikováno v: Frontiers in Medicine, Vol 9 (2022)

ObjectiveTo improve the fidelity of the cellular transcriptome of disaggregated synovial tissue for applications such as single-cell RNA sequencing (scRNAseq) by modifying the disaggregation technique.MethodsOsteoarthritis (OA) and rheumatoid arthrit

Externí odkaz: https://doaj.org/article/ca257da606bd4896b8f32896bbd4d85e

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Immunomodulatory Microparticles Epigenetically Modulate T Cells and Systemically Ameliorate Autoimmune Arthritis (Adv. Sci. 11/2023)

Autor: David A. McBride, Matthew D. Kerr, Wade T. Johnson, Anders Nguyen, Martina Zoccheddu, Mina Yao, Edward B. Prideaux, Nicholas C. Dorn, Wei Wang, Mattias N.D. Svensson, Nunzio Bottini, Nisarg J. Shah

Publikováno v: Advanced Science. 10

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::47aa725fc66ac981d5e607962823a6a6
https://doi.org/10.1002/advs.202370064

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