Výsledky vyhledávání - "Edward B, Stelow"

Elektronická kniha

Biopsy Interpretation of the Head and Neck

Part of the highly regarded Biopsy Interpretation Series, this fully revised volume provides practical, highly illustrated information on the diagnosis and prognosis of the full range of biopsies of the various tissues of the head and neck region, in

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Akademický článek

Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies

Autor: Tanmoy Mondal, Gururaj N Shivange, Rachisan GT Tihagam, Evan Lyerly, Michael Battista, Divpriya Talwar, Roxanna Mosavian, Karol Urbanek, Narmeen S Rashid, J Chuck Harrell, Paula D Bos, Edward B Stelow, M Sharon Stack, Sanchita Bhatnagar, Jogender Tushir‐Singh

Publikováno v: EMBO Molecular Medicine, Vol 13, Iss 3, Pp 1-28 (2021)

Abstract Lack of effective immune infiltration represents a significant barrier to immunotherapy in solid tumors. Thus, solid tumor‐enriched death receptor‐5 (DR5) activating antibodies, which generates tumor debulking by extrinsic apoptotic cyto

Externí odkaz: https://doaj.org/article/e6ee9e69e03c47dd8affba2d3b2379e8

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Akademický článek

CRISPR knockout screening identifies combinatorial drug targets in pancreatic cancer and models cellular drug response

Autor: Karol Szlachta, Cem Kuscu, Turan Tufan, Sara J. Adair, Stephen Shang, Alex D. Michaels, Matthew G. Mullen, Natasha Lopes Fischer, Jiekun Yang, Limin Liu, Prasad Trivedi, Edward B. Stelow, P. Todd Stukenberg, J. Thomas Parsons, Todd W. Bauer, Mazhar Adli

Publikováno v: Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)

Predicting the response to chemotherapy is a major goal of cancer research. Here the authors use CRISPR knockout screens in pancreatic ductal adenocarcinoma cells to identify deletions synergistic with MEK inhibitors.

Externí odkaz: https://doaj.org/article/5878576fa2b34029942f52a332a9c423

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The World Health Organization Reporting System for Pancreaticobiliary Cytopathology

Autor: Martha B. Pitman, Barbara A. Centeno, Michelle D. Reid, Momin T. Siddiqui, Lester J. Layfield, Miguel Perez-Machado, Birgit Weynand, Edward B. Stelow, Maria D. Lozano, Noriyoshi Fukushima, Ian A. Cree, Ravi Mehrotra, Fernando C. Schmitt, Andrew S. Field

Publikováno v: Acta Cytologica. :1-17

The World Health Organization (WHO), the International Academy of Cytology, and the International Agency for Research on Cancer, with expert contributors from around the world, present an international approach to standardized reporting of pancreatic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2bd1082bb06703a62931c55ccb853bb
https://doi.org/10.1159/000527912

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Akademický článek

Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth

Autor: Sarbajeet Nagdas, Jennifer A. Kashatus, Aldo Nascimento, Syed S. Hussain, Riley E. Trainor, Sarah R. Pollock, Sara J. Adair, Alex D. Michaels, Hiromi Sesaki, Edward B. Stelow, Todd W. Bauer, David F. Kashatus

Publikováno v: Cell Reports, Vol 28, Iss 7, Pp 1845-1859.e5 (2019)

Summary: Mitochondria undergo fission and fusion to maintain homeostasis, and tumors exhibit the dysregulation of mitochondrial dynamics. We recently demonstrated that ectopic HRasG12V promotes mitochondrial fragmentation and tumor growth through Erk

Externí odkaz: https://doaj.org/article/3897e3f059e04a41b0a0865493500ca3

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