Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Edward A. Smuckler"'
Publikováno v:
Molecular and Cellular Biochemistry. 48:3-14
Insulin binding sites are present on purified nuclear envelopes from liver and other tissues, and EM autoradiographs and other types of studies indicate that insulin can enter intact target cells and interact with several types of intracellular membr
Publikováno v:
Toxicology and Applied Pharmacology. 103:16-27
Phenobarbital treatment induces an isozyme(s) of liver microsomal cytochrome P450 susceptible to CCl4 and enhances the latter's lethality. We have now studied phenobarbital's effect on the specificity of phosphatidyl fatty acid changes in rat liver m
Autor:
Gary A. Clawson, Edward A. Smuckler
Publikováno v:
Biochemical and Biophysical Research Communications. 96:812-816
Nuclear envelopes were isolated from rat-liver nuclei. Nuclear envelope-associated RNA was isolated and hybridized to filter-bound DNA in the presence of competing RNA populations. Cytoplasmic RNA did not effectively compete for DNA binding sites, wh
Publikováno v:
Experimental Cell Research. 167:559-562
The major nucleoside triphosphatase of rat liver nuclear scaffold, a 46 kD protein thought to participate in nucleocytoplasmic RNA translocation, is distinct from immunologically-identified scaffold actin on Western blots, has a substantially differe
Publikováno v:
Proceedings of the National Academy of Sciences. 79:7522-7526
Cloned DNA probes were used to test for hepatitis B virus (HBV) DNA in the liver and serum of 14 asymptomatic hepatitis B surface antigen (HBsAg) carriers and two former carriers. The results were compared with serological markers of HBV infection an
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 388:339-348
Cholesteryl ester hydrolyzing activity of rat liver plasma membranes was studied using acetone-dispersed [4-14-C] cholesteryl oleate as substrate. In contrast to whole liver homogenates which displayed ample activity at both acid (4.5) and neutral (6
Autor:
Earl D. Baumgartel, Henry I. Goldberg, Lawrence W. Way, Roy A. Filly, Robert K. Ockner, Rudi Schmid, John P. Cello, Howard A. Shapiro, Marvin H. Sleisenger, Edward A. Smuckler, Alexander R. Margulis
Publikováno v:
Gastroenterology. 73:357-374
Autor:
Jacqueline L. James, C. H. Woo, Gary A. Clawson, Daniel S. Friend, Edward A. Smuckler, David E. Moody
Publikováno v:
Biochemistry. 19:2748-2756
Autor:
Edward A. Smuckler
Publikováno v:
Environmental Health Perspectives
Carbon tetrachloride produces liver cell injury in a variety of animal species. The first structurally recognizable changes occur in the endoplasmic reticulum, with alteration in ribosome-membrane interactions. Later there is an increase in intracell
Publikováno v:
Biochemistry. 23:3501-3507
We employed the photoaffinity probe 8-azido-adenosine 5'-triphosphate (aATP) to identify the nuclear envelope (NE) nucleosidetriphosphatase activity (NTPase) implicated in control of RNA transport. The photoprobe was hydrolyzed at rates comparable to