Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Edward A. K. Cohen"'
Autor:
Sophia F. Mersmann, Emma Johns, Tracer Yong, Will A. McEwan, Leo C. James, Edward A. K. Cohen, Joe Grove
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Cellular biology occurs through myriad interactions between diverse molecular components, many of which assemble in to specific complexes. Various techniques can provide a qualitative survey of which components are found in a given complex.
Externí odkaz:
https://doaj.org/article/4d53143895cd40149759320005fe4a26
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
The resolution limitations when using the ubiquitous algorithms that process images obtained using modern techniques are not straightforward to define. Here, the authors examine the performance of localization algorithms and use spatial statistics to
Externí odkaz:
https://doaj.org/article/242b06ba05364ba7b06cd448ca904f52
Autor:
Juliette Griffié, Leigh Shlomovich, David J. Williamson, Michael Shannon, Jesse Aaron, Satya Khuon, Garth L. Burn, Lies Boelen, Ruby Peters, Andrew P. Cope, Edward A. K. Cohen, Patrick Rubin-Delanchy, Dylan M. Owen
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract Single-molecule localisation microscopy (SMLM) allows the localisation of fluorophores with a precision of 10–30 nm, revealing the cell’s nanoscale architecture at the molecular level. Recently, SMLM has been extended to 3D, providing a
Externí odkaz:
https://doaj.org/article/e1603020fe654feab63ef71a07e8c512
Autor:
Daniel J. Nieves, Jeremy A. Pike, Florian Levet, David J. Williamson, Mohammed Baragilly, Sandra Oloketuyi, Ario de Marco, Juliette Griffié, Daniel Sage, Edward A. K. Cohen, Jean-Baptiste Sibarita, Mike Heilemann, Dylan M. Owen
Publikováno v:
Nature Methods. 20:259-267
This analysis compares the performance of seven algorithms for cluster analysis of single-molecule localization microscopy data. The results provide a framework for comparing these types of methods and point users to the best tools.
Single-molec
Single-molec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dffce103240f0caded806d5e89497481
https://doi.org/10.1038/s41592-022-01750-6
https://doi.org/10.1038/s41592-022-01750-6
Publikováno v:
Statistics and Computing. 32
It is often assumed that events cannot occur simultaneously when modelling data with point processes. This raises a problem as real-world data often contains synchronous observations due to aggregation or rounding, resulting from limitations on recor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c1ba727515bb1ed3811fd41669906afc
https://doi.org/10.1007/s11222-022-10121-2
https://doi.org/10.1007/s11222-022-10121-2
Autor:
Youssef Taleb, Edward A. K. Cohen
Publikováno v:
Annals of the Institute of Statistical Mathematics. 73:395-423
We take a wavelet based approach to the analysis of point processes and the estimation of the first order intensity under a continuous time setting. A Haar wavelet multiresolution analysis of a point process is formulated which motivates the definiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bad5e689e57f95bac211eb5d0b22c982
https://doi.org/10.1007/s10463-020-00753-4
https://doi.org/10.1007/s10463-020-00753-4
A key difficulty that arises from real event data is imprecision in the recording of event time-stamps. In many cases, retaining event times with a high precision is expensive due to the sheer volume of activity. Combined with practical limits on the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f954cf0fba40463265bcee83d928a84a
http://hdl.handle.net/10044/1/95850
http://hdl.handle.net/10044/1/95850
Autor:
Juliette Griffié, Mike Heilemann, Daniel Sage, Daniel J. Nieves, Dylan M. Owen, Jeremy A. Pike, Edward A. K. Cohen, Florian Levet, Jean-Baptiste Sibarita
Single molecule localisation microscopy (SMLM) generates data in the form of Cartesian coordinates of localised fluorophores. Cluster analysis is an attractive route for extracting biologically meaningful information from such data and has been widel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d7276ea30bd946bce582d480f831b9c
https://doi.org/10.1101/2021.06.19.449098
https://doi.org/10.1101/2021.06.19.449098
Publikováno v:
Spatial Statistics
There is currently a gap in theory for point patterns that lie on the surface of objects, with researchers focusing on patterns that lie in a Euclidean space, typically planar and spatial data. Methodology for planar and spatial data thus relies on E
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6351e130925b293fd6ba67a2867a019
http://europepmc.org/articles/PMC7903323
http://europepmc.org/articles/PMC7903323
Publikováno v:
Optics Express
Single-molecule microscopy allows for the investigation of the dynamics of individual molecules and the visualization of subcellular structures at high spatial resolution. For single-molecule imaging experiments, and particularly those that entail th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9547d6af53b395883ef39e9cc907dca
https://pubmed.ncbi.nlm.nih.gov/33362108
https://pubmed.ncbi.nlm.nih.gov/33362108