Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Edward A. Hayter"'
Autor:
Alessandra Stangherlin, Joseph L. Watson, David C. S. Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D. Beale, Edward A. Hayter, Alina Guna, Alison J. Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M. Voorhees, David A. Bechtold, Emmanuel Derivery, Rachel S. Edgar, Peter Newham, John S. O’Neill
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Osmotic compensation by electroneutral ion transport buffers TORC1-mediated changes in the cytosolic proteome, and maintains intracellular homeostasis and cell volume over the circadian cycle. Here, the authors find such ion content changes drive dai
Externí odkaz:
https://doaj.org/article/d608bbcc713a4841b6211ae27b0bfe88
Autor:
Edward A. Hayter, Sophie M. T. Wehrens, Hans P. A. Van Dongen, Alessandra Stangherlin, Shobhan Gaddameedhi, Elena Crooks, Nichola J. Barron, Luigi A. Venetucci, John S. O’ Neill, Timothy M. Brown, Debra J. Skene, Andrew W. Trafford, David A. Bechtold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Cardiac function fluctuates greatly across the day and night, but this is not simply a consequence of our changing behaviour. The authors highlight the role of the body’s circadian clock in regulating the heart electrical activity, including a time
Externí odkaz:
https://doaj.org/article/530c60e952014c1cb2858a92a8c76775
Autor:
Sarika Paul, Lydia Hanna, Court Harding, Edward A. Hayter, Lauren Walmsley, David A. Bechtold, Timothy M. Brown
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
VIP-expressing neurons play a central role in circadian timekeeping within the mammalian central clock. Here the authors use opto- and chemogenetic approaches to show that VIP neuronal activity regulates rhythmic activity in downstream hypothalamic t
Externí odkaz:
https://doaj.org/article/16d76bcc2be2406ea4926ed3ab5d9eeb
Autor:
Edward A. Hayter, Timothy M. Brown
Publikováno v:
BMC Biology, Vol 16, Iss 1, Pp 1-24 (2018)
Abstract Background Intrinsically photosensitive retinal ganglion cells (ipRGCs) drive an array of non-image-forming (NIF) visual responses including circadian photoentrainment and the pupil light reflex. ipRGCs integrate extrinsic (rod/cone) and int
Externí odkaz:
https://doaj.org/article/4b848d8cbc1640f9878f409cff8f1096
Autor:
Edward A. Hayter, Sophie M. T. Wehrens, Hans P. A. Van Dongen, Alessandra Stangherlin, Shobhan Gaddameedhi, Elena Crooks, Nichola J. Barron, Luigi A. Venetucci, John S. O’Neill, Timothy M. Brown, Debra J. Skene, Andrew W. Trafford, David A. Bechtold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/af3e22bd3d8c486d8552720ff8489fea
Autor:
Alessandra Stangherlin, Joseph L. Watson, David C. S. Wong, Silvia Barbiero, Aiwei Zeng, Estere Seinkmane, Sew Peak Chew, Andrew D. Beale, Edward A. Hayter, Alina Guna, Alison J. Inglis, Marrit Putker, Eline Bartolami, Stefan Matile, Nicolas Lequeux, Thomas Pons, Jason Day, Gerben van Ooijen, Rebecca M. Voorhees, David A. Bechtold, Emmanuel Derivery, Rachel S. Edgar, Peter Newham, John S. O’Neill
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/ce8210b5c1134255b82aa740bd07ccb6
Autor:
Andrew D. Beale, Priya Crosby, Utham Kashyap Valekunja, Rachel S Edgar, Johanna Chesham, Elizabeth Maywood, Fatima Hanna Labeed, Akhilesh B Reddy, Kenneth P Wright, Kathryn S. Lilley, Michael Harvey Hastings, John Stuart O'Neill, David A Bechtold, Edward A Hayter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49191be61e5bbd716964e321a87677be
https://doi.org/10.15252/rc.2023492254
https://doi.org/10.15252/rc.2023492254
Autor:
Elena Crooks, Sophie M T Wehrens, Hans P. A. Van Dongen, Luigi Venetucci, Shobhan Gaddameedhi, Timothy M. Brown, John S. O’ Neill, Debra J. Skene, Andrew W. Trafford, Edward A. Hayter, Nichola J Barron, David A. Bechtold, Alessandra Stangherlin
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Nature Communications
Hayter, E A, Wehrens, S M T, Van Dongen, H P A, Stangherlin, A, Gaddameedhi, S, Crooks, E, Barron, N J, Venetucci, L A, Neill, J S O, Brown, T M, Skene, D J, Trafford, A W & Bechtold, D A 2021, ' Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia ', Nature Communications, vol. 12, no. 1, 2472 . https://doi.org/10.1038/s41467-021-22788-8
Nature Communications
Hayter, E A, Wehrens, S M T, Van Dongen, H P A, Stangherlin, A, Gaddameedhi, S, Crooks, E, Barron, N J, Venetucci, L A, Neill, J S O, Brown, T M, Skene, D J, Trafford, A W & Bechtold, D A 2021, ' Distinct circadian mechanisms govern cardiac rhythms and susceptibility to arrhythmia ', Nature Communications, vol. 12, no. 1, 2472 . https://doi.org/10.1038/s41467-021-22788-8
Electrical activity in the heart exhibits 24-hour rhythmicity, and potentially fatal arrhythmias are more likely to occur at specific times of day. Here, we demonstrate that circadian clocks within the brain and heart set daily rhythms in sinoatrial
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9799ab86b9df430aa2acc3f981e5e2a
https://doaj.org/article/530c60e952014c1cb2858a92a8c76775
https://doaj.org/article/530c60e952014c1cb2858a92a8c76775
Autor:
Polly Downton, Fabio Sanna, Robert Maidstone, Toryn M. Poolman, Edward A. Hayter, Suzanna H. Dickson, Nick A. Ciccone, James O. Early, Antony Adamson, David G. Spiller, Devin A. Simpkins, Matthew Baxter, Roman Fischer, Magnus Rattray, Andrew S. I. Loudon, Julie E. Gibbs, David A. Bechtold, David W. Ray
Publikováno v:
Downton, P, Sanna, F, Maidstone, R, Poolman, T, Hayter, E, Dickson, S, Early, J, Adamson, A, Spiller, D, Simpkins, D, Baxter, M, Fischer, R, Rattray, M, Loudon, A, Gibbs, J, Bechtold, D & Ray, D 2022, ' Chronic inflammatory arthritis drives systemic changes in circadian energy metabolism ', PNAS . https://doi.org/10.1073/pnas.2112781119
Chronic inflammation underpins many human diseases. Morbidity and mortality associated with chronic inflammation are often mediated through metabolic dysfunction. Inflammatory and metabolic processes vary through circadian time, suggesting an importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::017529c2364b29af243534f1e7291915
https://research.manchester.ac.uk/en/publications/800a87b1-8e94-4db1-bc84-0c5accdfbaf1
https://research.manchester.ac.uk/en/publications/800a87b1-8e94-4db1-bc84-0c5accdfbaf1
Autor:
Rachel S. Edgar, Andrew D. Beale, Estere Seinkmane, Edward A. Hayter, Alison J. Inglis, Joseph L. Watson, Emmanuel Derivery, Thomas Pons, Sew Peak Chew, Stefan Matile, Aiwei Zeng, Jason Day, Alessandra Stangherlin, Nicolas Lequeux, Rebecca M. Voorhees, Gerben van Ooijen, Silvia Barbiero, John S. O’Neill, Peter Newham, David C S Wong, Marrit Putker, Eline Bartolami, Alina Guna, David A. Bechtold
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Nature Communications
Nature Communications
Between 6-20% of the cellular proteome is under circadian control and tunes mammalian cell function with daily environmental cycles. For cell viability, and to maintain volume within narrow limits, the daily variation in osmotic potential exerted by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db0acfb0784324a2a1b275d73b8240e3
http://hdl.handle.net/10044/1/104009
http://hdl.handle.net/10044/1/104009