Zobrazeno 1 - 10 of 96 pro vyhledávání: '"Edward A. Burgess"'
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Akademický článek
Anti-inflammatory effects of levalbuterol-induced 11β-hydroxysteroid dehydrogenase type 1 activity in airway epithelial cells
Autor: Matthew J Randall, Shannon F Kostin, Edward J Burgess, Laura R Hoyt, Jennifer L Ather, Lennart K Lundblad, Matthew E Poynter
Publikováno v: Frontiers in Endocrinology, Vol 5 (2015)
Airway epithelial NF-kB activation is observed in asthmatic subjects and is a cause of airway inflammation in mouse models of allergic asthma. Combination therapy with inhaled short-acting b2-agonists and corticosteroids significantly improves lung f
Externí odkaz: https://doaj.org/article/77fb0ab0a86548889db97ae18df75815
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Bacterial Lipoproteins Constitute the TLR2-Stimulating Activity of Serum Amyloid A
Autor: Joseph J. Bivona, Bryan A. Ballif, Philip Eisenhauer, Madeleine M Mank, Matthew J. Randall, Jonathan E. Boyson, Laura R. Hoyt, Jennifer L. Ather, Edward J. Burgess, Matthew E. Poynter, Matthew J. Wargo, Jason Botten, Ying-Wai Lam
Publikováno v: The Journal of Immunology. 201:2377-2384
Studies comparing endogenous and recombinant serum amyloid A (SAA) have generated conflicting data on the proinflammatory function of these proteins. In exploring this discrepancy, we found that in contrast to commercially sourced recombinant human S
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcea101fea0076d459933252ed0a7689
https://doi.org/10.4049/jimmunol.1800503
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3
Uricase Inhibits Nitrogen Dioxide-Promoted Allergic Sensitization to Inhaled Ovalbumin Independent of Uric Acid Catabolism
Autor: Jonathan E. Boyson, Matthew J. Randall, Dwight E. Matthews, Laura R. Hoyt, Jennifer L. Ather, Mridul Kanti Mandal, Edward J. Burgess, Matthew E. Poynter
Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 197(5)
Nitrogen dioxide (NO2) is an environmental air pollutant and endogenously generated oxidant that contributes to the exacerbation of respiratory disease and can function as an adjuvant to allergically sensitize to an innocuous inhaled Ag. Because uric
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2285865ca872e583a95958b71f53875d
https://pubmed.ncbi.nlm.nih.gov/27465529
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4
Synthesis and MEK1 inhibitory activities of imido-Substituted 2-chloro-1,4-naphthoquinones
Autor: Hairuo Peng, Edward M. Burgess, Oladapo Bakare, Leon H. Zalkow, Curtis L. Ashendel
Publikováno v: Bioorganic & Medicinal Chemistry. 11:3165-3170
Mitogen activated protein kinases are of interest as research tools and as therapeutic target for certain physiological disorders. In this study, we found 2-chloro-3-(N-succinimidyl)-1,4-naphthoquinone 6 to be a selective inhibitor of MEK1 with an IC
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d90941c4c6d87ee242491f35bfaefaa7
https://doi.org/10.1016/s0968-0896(03)00267-0
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5
A Novel Route to an Aza Analog of the Marine Natural Product Damirone B
Autor: Oladapo Bakare, Edward M. Burgess, Leon H. Zalkow
Publikováno v: Synthetic Communications. 27:1569-1576
3-(N-carboalkoxyamino)-1-diazopropane has been used as a difunctional synthon for a three step synthesis of pyrazolo[5,4,3-de]-1,2,3,6,7-pentahydroquinolin-6,7-dione, a tricyclic aza analog of the marine natural product Damirone B.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ded03b0e1a66203daba20646d49951ad
https://doi.org/10.1080/00397919708006095
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6
Inhibition of Porcine Pancreatic Elastase by 7-Substituted 4-Chloro-3-Ethoxyisocoumarins: Structural Characteristics of Modeled Noncovalent Complexes Relate to the Measured Inhibition Kinetics
Autor: James C. Powers, Edward M. Burgess, John E. Kerrigan, R. Richard Plaskon, F. L. Suddath, Chih-Min Kam
Publikováno v: Archives of Biochemistry and Biophysics. 300:588-597
Kinetic measurements for the inhibition of porcine pancreatic elastase by 7-substituted 4-chloro-.3-ethox-yisocoumarins were performed. To obtain possible explanations for the kinetic results, structures resulting from energy minimizations of inhibit
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba46bbe5a7800a79b915bb49e9bf103c
https://doi.org/10.1006/abbi.1993.1082
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8
The Role of Computer Modeling in Combined Sewer Overflow Abatement Planning
Autor: Edward H. Burgess, Larry A. Roesner
Publikováno v: Water Science and Technology. 26:1831-1840
Increased concern regarding water quality impacts from combined sewer overflows (CSOs) in the U.S. and elsewhere has emphasized the role of computermodeling in analyzing CSO impacts and in planning abatement measures. These measures often involve the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ae4134271c8daa3b670623b4e33a7646
https://doi.org/10.2166/wst.1992.0627
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9
Synthesis of 3-[(N-carboalkoxy)ethylamino]-indazole-dione derivatives and their biological activities on human liver carbonyl reductase
Autor: Andrew M. Slupe, Edward M. Burgess, Solomon Berhe, Don L. Warner, Nkechi M. Enwerem, L.H. Zalkow, Choice Luster, Oladapo Bakare, Henry A. Charlier
Publikováno v: Bioorganicmedicinal chemistry. 18(1)
A series of indazole-dione derivatives were synthesized by the 1,3-dipolar cycloaddition reaction of appropriate substituted benzoquinones or naphthoquinones and N-carboalkoxyamino diazopropane derivatives. These compounds were evaluated for their ef
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7cb9058e145a5a2631e070843ebf461
https://pubmed.ncbi.nlm.nih.gov/19959367
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