Výsledky vyhledávání - "Edward A. Bedoya"

Conditional deletion of the glutamate transporter GLT-1 reveals that astrocytic GLT-1 protects against fatal epilepsy while neuronal GLT-1 contributes significantly to glutamate uptake into synaptosomes

Autor: Paul A. Rosenberg, Kathryn D. Fischer, Niels C. Danbolt, Clive Miranda, Wencke Armsen, Geraldine T. Petr, Yun Zhou, Natalie M. Frederick, Mustafa Q. Hameed, Edward A. Bedoya, Sameer C. Dhamne, Yan Sun, Alexander Rotenberg, Jianlin Wang, Chiye Aoki

Publikováno v: The Journal of neuroscience : the official journal of the Society for Neuroscience. 35(13)

GLT-1 (EAAT2; slc1a2) is the major glutamate transporter in the brain, and is predominantly expressed in astrocytes, but at lower levels also in excitatory terminals. We generated a conditional GLT-1 knock-out mouse to uncover cell-type-specific func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::265e5b9915f9b2b05fadcf7187e2dafd
https://pubmed.ncbi.nlm.nih.gov/25834045

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