Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Edward A Nam"'
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004552 (2015)
Data integration procedures combine heterogeneous data sets into predictive models, but they are limited to data explicitly related to the target object type, such as genes. Collage is a new data fusion approach to gene prioritization. It considers d
Externí odkaz:
https://doaj.org/article/3db88e6e2baf476282ff43473e8cb746
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99397 (2014)
Subcellular localization, protein interactions, and post-translational modifications regulate the DNA damage response kinases ATR, ATM, and DNA-PK. During an analysis of putative ATR phosphorylation sites, we found that a single mutation at S1333 cre
Externí odkaz:
https://doaj.org/article/02b19fd7ea9e4355a8c0f3b1cd9b3b13
Autor:
Ludmila Tyler, Yuji Kamiya, Jeongmoo Park, Jikumaru Yusuke, Edward A. Nam, Kai Qiu, Shelley Lumba, Darrell Desveaux, Xin Zhou, Tai-ping Sun, Peter McCourt, Zhong-Lin Zhang
Publikováno v:
Plant Physiology. 171:2760-2770
The phytohormone gibberellin (GA) plays a key role in promoting stem elongation in plants. Previous studies show that GA activates its signaling pathway by inducing rapid degradation of DELLA proteins, GA signaling repressors. Using an activation-tag
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e7fe857b2849e5bb6e2c67e4dc3c0bb
https://doi.org/10.1104/pp.16.00154
https://doi.org/10.1104/pp.16.00154
Publikováno v:
Journal of Biological Chemistry. 286:37320-37327
ATR (ataxia telangiectasia-mutated and Rad3-related) contains 16 conserved candidate autophosphorylation sites that match its preferred S/TQ consensus. To determine whether any is functionally important, we mutated the 16 candidate residues to alanin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad60c195141bfc63d23b9a4bba0620e9
https://doi.org/10.1074/jbc.m111.276113
https://doi.org/10.1074/jbc.m111.276113
Autor:
David B. Friedman, Runxiang Zhao, David Cortez, Gloria G. Glick, Carol E. Bansbach, Edward A. Nam
Publikováno v:
Journal of Biological Chemistry. 286:28707-28714
The DNA damage response kinases ataxia telangiectasia-mutated (ATM), DNA-dependent protein kinase (DNA-PK), and ataxia telangiectasia-mutated and Rad3-related (ATR) signal through multiple pathways to promote genome maintenance. These related kinases
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ebeee33e321bf24d30332717b803aa5
https://doi.org/10.1074/jbc.m111.248914
https://doi.org/10.1074/jbc.m111.248914
Autor:
David Cortez, Edward A. Nam
Publikováno v:
Biochemical Journal. 436:527-536
Preservation of genome integrity via the DNA-damage response is critical to prevent disease. ATR (ataxia telangiectasia mutated- and Rad3-related) is essential for life and functions as a master regulator of the DNA-damage response, especially during
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dcb523d4a8fb14b7496d14b280cb85f
https://doi.org/10.1042/bj20102162
https://doi.org/10.1042/bj20102162
Autor:
Wei-Chu Lai, Joseph R. Ecker, Tai-ping Sun, Jianhong Hu, Stephen M. Swain, Belay T. Ayele, Atsushi Hanada, Edward A. Nam, Yuji Kamiya, Melissa G. Mitchum, Neel Barnaby, Shinjiro Yamaguchi, Mikihiro Ogawa, Jose M. Alonso
Publikováno v:
The Plant Cell. 20:320-336
Gibberellin 3-oxidase (GA3ox) catalyzes the final step in the synthesis of bioactive gibberellins (GAs). We examined the expression patterns of all four GA3ox genes in Arabidopsis thaliana by promoter–β-glucuronidase gene fusions and by quantitati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed17f460e323b9d9ede3d30897c0d217
https://doi.org/10.1105/tpc.107.057752
https://doi.org/10.1105/tpc.107.057752
Publikováno v:
PLoS Computational Biology, Vol 11, Iss 10, p e1004552 (2015)
PLoS Computational Biology
PLoS Computational Biology
Data integration procedures combine heterogeneous data sets into predictive models, but they are limited to data explicitly related to the target object type, such as genes. Collage is a new data fusion approach to gene prioritization. It considers d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ddf4e5b1654ad621856c14ac1782fb56
http://europepmc.org/articles/PMC4605714?pdf=render
http://europepmc.org/articles/PMC4605714?pdf=render
Autor:
Eui Hang Shin, Edward A. Nam
Publikováno v:
Journal of Sport and Social Issues. 28:223-244
The success of multiple Korean women on the LPGA tour a decade ago was unheard of; today it is the norm. In the past 5 years, Koreans have joined the tour as rookies of the year, won major championships, and topped money lists. The timing of the succ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76b57608d530b1d1cedd887975c0d9f6
https://doi.org/10.1177/0193723504266993
https://doi.org/10.1177/0193723504266993
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 6, p e99397 (2014)
PLoS ONE, Vol 9, Iss 6, p e99397 (2014)
Subcellular localization, protein interactions, and post-translational modifications regulate the DNA damage response kinases ATR, ATM, and DNA-PK. During an analysis of putative ATR phosphorylation sites, we found that a single mutation at S1333 cre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29043857ba9857a5e166d34ebdb0807e
http://europepmc.org/articles/PMC4047089
http://europepmc.org/articles/PMC4047089