Zobrazeno 1 - 10
of 210
pro vyhledávání: '"Edward A Hoover"'
Autor:
Davin M Henderson, Nathaniel D Denkers, Clare E Hoover, Erin E McNulty, Sarah K Cooper, Lauren A Bracchi, Candace K Mathiason, Edward A Hoover
Publikováno v:
PLoS ONE, Vol 15, Iss 2, p e0228327 (2020)
Chronic wasting disease (CWD) continues to spread or be recognized in the United States, Canada, and Europe. CWD is diagnosed by demonstration of the causative misfolded prion protein (PrPCWD) in either brain or lymphoid tissue using immunodetection
Externí odkaz:
https://doaj.org/article/fee6c1e1f1704280a3563561e88077b1
Autor:
Joanne M Tennant, Manci Li, Davin M Henderson, Margaret L Tyer, Nathaniel D Denkers, Nicholas J Haley, Candace K Mathiason, Edward A Hoover
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0227094 (2020)
CWD is an emergent prion disease that now affects cervid species on three continents. CWD is efficiently spread in wild and captive populations, likely through both direct animal contact and environmental contamination. Here, by longitudinally assayi
Externí odkaz:
https://doaj.org/article/aba7d3cdedda4f67a9a0b0beab69ef84
Autor:
Nathaniel D Denkers, Clare E Hoover, Kristen A Davenport, Davin M Henderson, Erin E McNulty, Amy V Nalls, Candace K Mathiason, Edward A Hoover
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237410 (2020)
The minimum infectious dose required to induce CWD infection in cervids remains unknown, as does whether peripherally shed prions and/or multiple low dose exposures are important factors in CWD transmission. With the goal of better understand CWD inf
Externí odkaz:
https://doaj.org/article/cca47ac598124311849de7ecbf8bb64c
Autor:
Sarah K Cooper, Clare E Hoover, Davin M Henderson, Nicholas J Haley, Candace K Mathiason, Edward A Hoover
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221654 (2019)
The diagnosis of chronic wasting disease (CWD) relies on demonstration of the disease-associated misfolded CWD prion protein (PrPCWD) in brain or retropharyngeal lymph node tissue by immunodetection methods, e.g. ELISA and immunohistochemistry (IHC).
Externí odkaz:
https://doaj.org/article/bf4290ff7f0149f4b517066f4f00a542
Autor:
Erin McNulty, Amy V Nalls, Samuel Mellentine, Erin Hughes, Laura Pulscher, Edward A Hoover, Candace K Mathiason
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216621 (2019)
Longitudinal studies of chronic wasting disease (CWD) in the native host have provided considerable understanding of how this prion disease continues to efficiently spread among cervid species. These studies entail great cost in animal, time and fina
Externí odkaz:
https://doaj.org/article/64b6df70a6b54b9d85e9b99ef32f9d3b
Autor:
Nathaniel D. Denkers, Erin E. McNulty, Caitlyn N. Kraft, Amy V. Nalls, Joseph A. Westrich, Edward A. Hoover, Candace K. Mathiason
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 10, Pp 2118-2127 (2024)
Chronic wasting disease (CWD) affects cervids in North America, Asia, and Scandinavia. CWD is unique in its efficient spread, partially because of contact with infectious prions shed in secreta. To assess temporal profiles of CWD prion shedding, we c
Externí odkaz:
https://doaj.org/article/5ddaf5bafe3e40ae9c39954d6f944a01
Autor:
Kristen A Davenport, Clare E Hoover, Jifeng Bian, Glenn C Telling, Candace K Mathiason, Edward A Hoover
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0183927 (2017)
The agent responsible for prion diseases is a misfolded form of a normal protein (PrPC). The prion hypothesis stipulates that PrPC must be present for the disease to manifest. Cervid populations across the world are infected with chronic wasting dise
Externí odkaz:
https://doaj.org/article/d80f7c37160f48099f78dc9baf5883ca
Autor:
Alan M Elder, Davin M Henderson, Amy V Nalls, Jason M Wilham, Byron W Caughey, Edward A Hoover, Anthony E Kincaid, Jason C Bartz, Candace K Mathiason
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80203 (2013)
Blood-borne transmission of infectious prions during the symptomatic and asymptomatic stages of disease occurs for both human and animal transmissible spongiform encephalopathies (TSEs). The geographical distribution of the cervid TSE, chronic wastin
Externí odkaz:
https://doaj.org/article/8927ea0d72c7491d982e67ab5015856b
Autor:
Davin M Henderson, Matteo Manca, Nicholas J Haley, Nathaniel D Denkers, Amy V Nalls, Candace K Mathiason, Byron Caughey, Edward A Hoover
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e74377 (2013)
Chronic wasting disease (CWD) is an efficiently transmitted prion disease of cervids, now identified in 22 United States, 2 Canadian provinces and Korea. One hallmark of CWD is the shedding of infectious prions in saliva, as demonstrated by bioassay
Externí odkaz:
https://doaj.org/article/78508deffd904e08919c32ce847a6cca
Autor:
Amy V Nalls, Erin McNulty, Jenny Powers, Davis M Seelig, Clare Hoover, Nicholas J Haley, Jeanette Hayes-Klug, Kelly Anderson, Paula Stewart, Wilfred Goldmann, Edward A Hoover, Candace K Mathiason
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e71844 (2013)
The horizontal transmission of prion diseases has been well characterized in bovine spongiform encephalopathy (BSE), chronic wasting disease (CWD) of deer and elk and scrapie of sheep, and has been regarded as the primary mode of transmission. Few st
Externí odkaz:
https://doaj.org/article/cd7126f5739d484a85db00c9e7e863dc