Zobrazeno 1 - 10
of 272
pro vyhledávání: '"Edward A Berger"'
Autor:
Mary S Pampusch, Hadia M Abdelaal, Emily K Cartwright, Jhomary S Molden, Brianna C Davey, Jordan D Sauve, Emily N Sevcik, Aaron K Rendahl, Eva G Rakasz, Elizabeth Connick, Edward A Berger, Pamela J Skinner
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1009831 (2022)
During chronic human immunodeficiency virus (HIV) or simian immunodeficiency virus (SIV) infection prior to AIDS progression, the vast majority of viral replication is concentrated within B cell follicles of secondary lymphoid tissues. We investigate
Externí odkaz:
https://doaj.org/article/ec02b79848574b81a11bd4e2ead3af63
Publikováno v:
PLoS ONE, Vol 16, Iss 1, p e0245024 (2021)
Ebola virus (EBOV), a member of the mononegaviral family Filoviridae, causes severe disease associated with high lethality in humans. Despite enormous progress in development of EBOV medical countermeasures, no anti-EBOV treatment has been approved.
Externí odkaz:
https://doaj.org/article/520cc08e80134a52a681afdaa509a001
Autor:
Paul W Denton, Julie M Long, Stephen W Wietgrefe, Craig Sykes, Rae Ann Spagnuolo, Olivia D Snyder, Katherine Perkey, Nancie M Archin, Shailesh K Choudhary, Kuo Yang, Michael G Hudgens, Ira Pastan, Ashley T Haase, Angela D Kashuba, Edward A Berger, David M Margolis, J Victor Garcia
Publikováno v:
PLoS Pathogens, Vol 10, Iss 1, p e1003872 (2014)
Antiretroviral therapy (ART) can reduce HIV levels in plasma to undetectable levels, but rather little is known about the effects of ART outside of the peripheral blood regarding persistent virus production in tissue reservoirs. Understanding the dyn
Externí odkaz:
https://doaj.org/article/b0f7c03fdd304391a0a5799a98531508
Publikováno v:
PLoS Pathogens, Vol 7, Iss 4, p e1001333 (2011)
Numerous constraints significantly hamper the experimental study of hepatitis C virus (HCV). Robust replication in cell culture occurs with only a few strains, and is invariably accompanied by adaptive mutations that impair in vivo infectivity/replic
Externí odkaz:
https://doaj.org/article/660626157d944ef0b7e10446eb3e16c1
Autor:
Edward A Berger, Ira Pastan
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000803 (2010)
Externí odkaz:
https://doaj.org/article/ea296121f58c47dcbbb04d29d8952639
Autor:
Agnes Hajduczki, David T. Danielson, David S. Elias, Virgilio Bundoc, Aaron W. Scanlan, Edward A. Berger
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Anti-HIV chimeric antigen receptors (CARs) promote direct killing of infected cells, thus offering a therapeutic approach aimed at durable suppression of infection emerging from viral reservoirs. CD4-based CARs represent a favored option, since they
Externí odkaz:
https://doaj.org/article/51e28644b8834cc3a3603daee4ad41f2
Autor:
Emily K. Cartwright, Mary S. Pampusch, Aaron K. Rendahl, Edward A. Berger, Natalie Coleman-Fuller, Pamela J. Skinner
Publikováno v:
ImmunoHorizons. 6:693-704
Despite mounting a robust antiviral CD8 T cell response to HIV infection, most infected individuals are unable to control HIV viral load without antiretroviral therapy (ART). Chimeric Ag receptor (CAR) T cell treatment is under intensive investigatio
Autor:
Brianna C. Davey, Mary S. Pampusch, Emily K. Cartwright, Hadia M. Abdelaal, Eva G. Rakasz, Aaron Rendahl, Edward A. Berger, Pamela J. Skinner
Publikováno v:
Frontiers in Immunology. 13
T cells expressing a simian immunodeficiency (SIV)-specific chimeric antigen receptor (CAR) and the follicular homing molecule, CXCR5, were infused into antiretroviral therapy (ART) suppressed, SIV-infected rhesus macaques to assess their ability to
Autor:
Kumudhini Preethi Haran, Agnes Hajduczki, Mary S. Pampusch, Gwantwa Mwakalundwa, Diego A. Vargas-Inchaustegui, Eva G. Rakasz, Elizabeth Connick, Edward A. Berger, Pamela J. Skinner
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
There is a need to develop improved methods to treat and potentially cure HIV infection. During chronic HIV infection, replication is concentrated within T follicular helper cells (Tfh) located within B cell follicles, where low levels of virus-speci
Externí odkaz:
https://doaj.org/article/9595b40b4a22494fbe24e9a9f0ccd565
Autor:
Julianna S. Gesun, Allison Godwin, Edward J. Berger, Heather Perkins, John Chen, Justin Charles Major, Matthew Scheidt
Publikováno v:
International Journal of Community Well-Being. 4:549-580