Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Edward A, Phelps"'
Autor:
Denise M. Drotar, Ana Karen Mojica-Avila, Drew T. Bloss, Christian M. Cohrs, Cameron T. Manson, Amanda L. Posgai, MacKenzie D. Williams, Maigan A. Brusko, Edward A. Phelps, Clive H. Wasserfall, Stephan Speier, Mark A. Atkinson
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114346- (2024)
Summary: Histopathological heterogeneity in the human pancreas is well documented; however, functional evidence at the tissue level is scarce. Herein, we investigate in situ glucose-stimulated islet and carbachol-stimulated acinar cell secretion acro
Externí odkaz:
https://doaj.org/article/fcfd2fb1042a446182c1c09a0ce0ffd8
Autor:
Jorge Santini-González, Roberto Castro-Gutierrez, Matthew W. Becker, Chad Rancourt, Holger A. Russ, Edward A. Phelps
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
There is a critical need for therapeutic approaches that combine renewable sources of replacement beta cells with localized immunomodulation to counter recurrence of autoimmunity in type 1 diabetes (T1D). However, there are few examples of animal mod
Externí odkaz:
https://doaj.org/article/3b0ae6ffcae04f0facfe19791550e698
Publikováno v:
Advanced NanoBiomed Research, Vol 2, Iss 10, Pp n/a-n/a (2022)
Microporous annealed particle (MAP) hydrogels have emerged as a versatile biomaterial platform for regenerative medicine. MAP hydrogels have been used for the delivery of cells and organoids but often require annealing post‐injection by an external
Externí odkaz:
https://doaj.org/article/9251dd54fd5541fa949db901c2dad476
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Gamma aminobutyric acid (GABA) is a non-proteinogenic amino acid and neurotransmitter that is produced in the islet at levels as high as in the brain. GABA is synthesized by the enzyme glutamic acid decarboxylase (GAD), of which the 65 kDa isoform (G
Externí odkaz:
https://doaj.org/article/5efe1abe408146ce837f97c049f7a03c
Autor:
Rebecca S. Aguirre, Abhishek Kulkarni, Matthew W. Becker, Xiaoyong Lei, Soumyadeep Sarkar, Sasanka Ramanadham, Edward A. Phelps, Ernesto S. Nakayasu, Emily K. Sims, Raghavendra G. Mirmira
Publikováno v:
Molecular Metabolism, Vol 63, Iss , Pp 101545- (2022)
Background: Type 1 diabetes (T1D) is a complex autoimmune disorder whose pathogenesis involves an intricate interplay between β cells of the pancreatic islet, other islet cells, and cells of the immune system. Direct intercellular communication with
Externí odkaz:
https://doaj.org/article/678c7a50544c41d5811309036b14ae85
Publikováno v:
Bioengineering, Vol 8, Iss 11, p 161 (2021)
Given the incidence of corneal dysfunctions and diseases worldwide and the limited availability of healthy, human donors, investigators are working to generate engineered cellular and acellular therapeutic approaches as alternatives to corneal transp
Externí odkaz:
https://doaj.org/article/52d641fd1ba74f8c84b348c8005410c9
Autor:
Teresa L. Mastracci, Minoti Apte, Laufey T. Amundadottir, Alexandra Alvarsson, Steven Artandi, Melena D. Bellin, Ernesto Bernal-Mizrachi, Alejandro Caicedo, Martha Campbell-Thompson, Zobeida Cruz-Monserrate, Abdelfattah El Ouaamari, Kyle J. Gaulton, Andrea Geisz, Mark O. Goodarzi, Manami Hara, Rebecca L. Hull-Meichle, Alexander Kleger, Alison P. Klein, Janel L. Kopp, Rohit N. Kulkarni, Mandar D. Muzumdar, Anjaparavanda P. Naren, Scott A. Oakes, Søren S. Olesen, Edward A. Phelps, Alvin C. Powers, Cherie L. Stabler, Temel Tirkes, David C. Whitcomb, Dhiraj Yadav, Jing Yong, Norann A. Zaghloul, Stephen J. Pandol, Maike Sander
Publikováno v:
Diabetes.
In the article cited above, the affiliations for authors Stephen J. Pandol and Maike Sander were inadvertently transposed. The correct affiliation for Stephen J. Pandol is Department of Gastroenterology, Cedars-Sinai Medical Center, Los Angeles, CA.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc44c953819ad848ff947e0be7c5dc9a
https://doi.org/10.2337/db23-er08
https://doi.org/10.2337/db23-er08
Publikováno v:
Journal of Biomedical Materials Research Part A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89d44376717594a3da9c44bb7290f95a
https://doi.org/10.1002/jbm.a.37540
https://doi.org/10.1002/jbm.a.37540
Extracellular vesicles (EVs) are small, biologically active, cell-secreted vesicles that can affect immune responses through antigen presentation and co-stimulation or co-inhibition. We generated designer EVs to modulate autoreactive T cells in the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::79432c5304045e362f62f001eb64027a
https://doi.org/10.1101/2022.11.23.517693
https://doi.org/10.1101/2022.11.23.517693
Autor:
Clare Stokes, Jose A. Pino, D. Walker Hagan, Gonzalo E. Torres, Edward A. Phelps, Nicole A. Horenstein, Roger L. Papke
Publikováno v:
Addiction Biology. 27
The use of areca nuts (areca) in the form of betel quids constitutes the fourth most common addiction in the world, associated with high risk for oral disease and cancer. Areca is a complex natural product, making it difficult to identify specific co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f337902be44ca6e0a3459615a38e4dd1
https://doi.org/10.1111/adb.13223
https://doi.org/10.1111/adb.13223