Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Edward Kesicki"'
Autor:
Anke Klippel, Rui Wang, Loredana Puca, Andrew Lee Faber, Weihua Shen, Shripad V. Bhagwat, Kannan Karukurichi, Feiyu Fred Zhang, Carmen Perez, Ramon Rama, Ana Ramos, Yi Zheng, Zahid Bonday, James Thomas, Harold B. Brooks, Lisa J. Kindler, Sarah M. Bogner, Parisa Zolfaghari, Mark Hicks II, Sophie Callies, Brian Mattioni, Laurie LeBrun, Jim Durbin, Erin Anderson, Chris Mayne, Edward Kesicki, Gabrielle Kolakowski, Steven W. Andrews, Barbara J. Brandhuber
Publikováno v:
Molecular Cancer Therapeutics. 20:P142-P142
Phosphoinositide 3-kinase alpha (PI3Kα) H1047R mutations are activating oncogenic events that occur in ~15% of advanced breast cancers. While there is one PI3Kα inhibitor FDA-approved for patients with PI3Kα-mutated breast cancer, and many others
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb459fe49f4567505f299a0a126a63bb
https://doi.org/10.1158/1535-7163.targ-21-p142
https://doi.org/10.1158/1535-7163.targ-21-p142
Publikováno v:
The FASEB Journal. 28
TRPA1 functions as a ligand-gated cation channel in sensory neurons and is an important drug discovery target for identification of novel analgesics. We report identification of a novel structural class of ligands reversibly modulating TRPA1 channel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::19c7ba7b559a3b13bb187d74cd434314
https://doi.org/10.1096/fasebj.28.1_supplement.1061.7
https://doi.org/10.1096/fasebj.28.1_supplement.1061.7
Autor:
Paul Zhichkin, Edward Kesicki, Jennifer Treiberg, Lisa Bourdon, Matthew Ronsheim, Hua Chee Ooi, Stephen White, Angela Judkins, David Fairfax
Publikováno v:
Organic Letters; Mar2007, Vol. 9 Issue 7, p1415-1418, 4p