Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Edward, Pichinuk"'
Autor:
Einat Bigelman, Metsada Pasmanik-Chor, Bareket Dassa, Maxim Itkin, Sergey Malitsky, Orly Dorot, Edward Pichinuk, Yuval Kleinberg, Gad Keren, Michal Entin-Meer
Publikováno v:
PLoS ONE, Vol 18, Iss 8, p e0275550 (2023)
BackgroundRenal injury induces major changes in plasma and cardiac metabolites. Using a small- animal in vivo model, we sought to identify a key metabolite whose levels are significantly modified following an acute kidney injury (AKI) and to analyze
Externí odkaz:
https://doaj.org/article/590ab8165c2b4e95b0529559909cff2a
Autor:
Dana Laor, Dorin Sade, Shira Shaham-Niv, Dor Zaguri, Myra Gartner, Vasantha Basavalingappa, Avi Raveh, Edward Pichinuk, Hamutal Engel, Keita Iwasaki, Tatsuyuki Yamamoto, Hemanth Noothalapati, Ehud Gazit
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Small molecule metabolites like phenylalanine can form amyloid-like structures but so far this has only been demonstrated in vitro. Here the authors generate a yeast in vivo model of adenine self-assembly and characterize the adenine assemblies in ce
Externí odkaz:
https://doaj.org/article/378a668465b54f94a2144b2dc009b093
Autor:
Keren Masha Rabinowitz, Michal Navon, Hadar Edelman-Klapper, Eran Zittan, Ariella Bar-Gil Shitrit, Idan Goren, Irit Avni-Biron, Jacob E. Ollech, Lev Lichtenstein, Hagar Banai-Eran, Henit Yanai, Yifat Snir, Maor H. Pauker, Adi Friedenberg, Adva Levy-Barda, Arie Segal, Yelena Broitman, Eran Maoz, Baruch Ovadia, Maya Aharoni Golan, Eyal Shachar, Shomron Ben-Horin, Nitsan Maharshak, Michal Mor, Haim Ben Zvi, Rami Eliakim, Revital Barkan, Tali Sharar-Fischler, Sophy Goren, Noy Krugliak, Edward Pichinuk, Michael Mor, Michal Werbner, Joel Alter, Hanan Abu-Taha, Kawsar Kaboub, Moshe Dessau, Meital Gal-Tanamy, Dani Cohen, Natalia T. Freund, Iris Dotan, on behalf of the Responses to COVID-19 Vaccine Israeli IBD Group
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1186 (2022)
Patients with inflammatory bowel disease (IBD) treated with anti-tumor-necrosis factor-alpha (TNFα) exhibited lower serologic responses one-month following the second dose of the COVID-19 BNT162b2 vaccine compared to those not treated with anti-TNF
Externí odkaz:
https://doaj.org/article/002599bbb4e74664a74f8cb9e8c3051d
Publikováno v:
Disease Models & Mechanisms, Vol 10, Iss 5, Pp 645-654 (2017)
Amyotrophic lateral sclerosis (ALS) is an incurable motor neurodegenerative disease caused by a diversity of genetic and environmental factors that leads to neuromuscular degeneration and has pathophysiological implications in non-neural systems. Our
Externí odkaz:
https://doaj.org/article/6fa75a54250b404ba89fadca60b78789
Autor:
Dina Morein, Linor Rubinstein-Achiasaf, Hadar Brayer, Orly Dorot, Edward Pichinuk, Hagar Ben-Yaakov, Tsipi Meshel, Metsada Pasmanik-Chor, Adit Ben-Baruch
Publikováno v:
Cells, Vol 10, Iss 6, p 1356 (2021)
Chronic inflammation promotes cancer progression by affecting the tumor cells and their microenvironment. Here, we demonstrate that a continuous stimulation (~6 weeks) of triple-negative breast tumor cells (TNBC) by the proinflammatory cytokines tumo
Externí odkaz:
https://doaj.org/article/94384dac5686473185b1a7d1ff155cb3
Autor:
Johanna Zerbib, Daniel Aberdam, Edward Pichinuk, Elie Frank, Léa Zennaro, Keren Oved, Orly Dorot, Lauriane N. Roux, Dominique Bremond-Gignac
Publikováno v:
Biochemical and Biophysical Research Communications. 582:100-104
Aniridia is a panocular inherited rare eye disease linked to heterozygous mutations on the PAX6 gene, which fail to properly produce sufficient protein essential for normal eye development and function. Most of the patients suffer from aniridia-relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1238d9cea94e57a0c2d98fb696fc82
https://doi.org/10.1016/j.bbrc.2021.10.036
https://doi.org/10.1016/j.bbrc.2021.10.036
Autor:
Einat Bigelman, Metsada Pasmanik-Chor, Bareket Dassa, Maxim Itkin, Sergey Malitsky, Orly Dorot, Edward Pichinuk, Smadar Levin-Zaidman, Nili Dezorella, Atan Gross, Anastasia Abashidze, Yuval Kleinberg, Gad Keren, Michal Entin-Meer
BackgroundRenal injury induces major changes in plasma and cardiac metabolites. We sought to identify a key metabolite that may affect cardiac mitochondria following an acute kidney injury (AKI) that may be harnessed to protect the heart following an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b162f07eca3ecc820e806ce29850a4e5
https://doi.org/10.1101/2022.05.17.492275
https://doi.org/10.1101/2022.05.17.492275
Autor:
Michael Chalick, Oded Jacobi, Edward Pichinuk, Christian Garbar, Armand Bensussan, Alan Meeker, Ravit Ziv, Tania Zehavi, Nechama I Smorodinsky, John Hilkens, Franz-Georg Hanisch, Daniel B Rubinstein, Daniel H Wreschner
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165031 (2016)
Translation of mRNA in alternate reading frames (ARF) is a naturally occurring process heretofore underappreciated as a generator of protein diversity. The MUC1 gene encodes MUC1-TM, a signal-transducing trans-membrane protein highly expressed in hum
Externí odkaz:
https://doaj.org/article/e148be4c47a04d5dbe84a96ede250065
Autor:
Thierry Guillaume, Edward Pichinuk, Gabi Haran, Ravit Ginat-Koton, Armand Bensussan, Daniel B. Rubinstein, Michael Chalik, Daniel H. Wreschner, Alan K. Meeker, Christian Garbar, Ravit Ziv, Itai Benhar, Nechama I. Smorodinsky
Publikováno v:
Cancer Immunology, Immunotherapy. 69:1337-1352
Cleavage of the MUC1 glycoprotein yields two subunits, an extracellular alpha-subunit bound to a smaller transmembrane beta-subunit. Monoclonal antibodies (mAbs) directed against the MUC1 alpha-beta junction comprising the SEA domain, a stable cell-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::438462d48cd653cccf9d444c83021ea3
https://doi.org/10.1007/s00262-020-02547-2
https://doi.org/10.1007/s00262-020-02547-2
Autor:
Orly Dorot, Gad Keren, Metsada Pasmanik-Chor, Michal Entin-Meer, Sergey Malitsky, E B Bigelman, B D Dassa, A G Gross, Maxim Itkin, Edward Pichinuk, N M Dezorell
Publikováno v:
European Heart Journal. 42
Background Myocardial ischemia is a major cause of death in patients with renal dysfunction. In order to identify a key metabolite which may protect cardiac function following renal injury, we have recently performed a metabolomics profiling analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf273a4b77b5d51c47cfd2679394fd6b
https://doi.org/10.1093/eurheartj/ehab724.3224
https://doi.org/10.1093/eurheartj/ehab724.3224