Structural basis for sequence-specific recognition of guide and target strands by the Archaeoglobus fulgidus Argonaute protein

Autor: Elena Manakova, Edvardas Golovinas, Reda Pocevičiūtė, Giedrius Sasnauskas, Algirdas Grybauskas, Saulius Gražulis, Mindaugas Zaremba

Publikováno v: Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)

Abstract Argonaute (Ago) proteins are found in all three domains of life. The best-characterized group is eukaryotic Argonautes (eAgos). Being the structural core of RNA interference machinery, they use guide RNA molecules for RNA targeting. Prokaryo

Externí odkaz: https://doaj.org/article/0f7eee6fbabe4e34899b5ac49373ec1e

Structural basis for sequence-specific recognition of guide and target strands by the Archaeoglobus fulgidus Argonaute protein

Autor: Elena Manakova, Edvardas Golovinas, Reda Pocevičiūtė, Giedrius Sasnauskas, Algirdas Grybauskas, Saulius Gražulis, Mindaugas Zaremba

Argonaute (Ago) proteins are found in all three domains of life. The best-characterized group is eukaryotic Argonautes (eAgos). Being the structural core of RNA interference machinery, they use guide RNA molecules for RNA targeting. Prokaryotic Argon

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f25504ae25515b6b325082a2d41eef59
https://doi.org/10.21203/rs.3.rs-2305454/v1

Short prokaryotic Argonautes provide defence against incoming mobile genetic elements through NAD+ depletion

Autor: Mindaugas Zaremba, Donata Dakineviciene, Edvardas Golovinas, Evelina Zagorskaitė, Edvinas Stankunas, Anna Lopatina, Rotem Sorek, Elena Manakova, Audrone Ruksenaite, Arunas Silanskas, Simonas Asmontas, Algirdas Grybauskas, Ugne Tylenyte, Edvinas Jurgelaitis, Rokas Grigaitis, Kęstutis Timinskas, Česlovas Venclovas, Virginijus Siksnys

Publikováno v: Nature microbiology 7(11), 1857-1869 (2022). doi:10.1038/s41564-022-01239-0

Nature microbiology 7(11), 1857 - 1869 (2022). doi:10.1038/s41564-022-01239-0
Argonaute (Ago) proteins are found in all three domains of life. The so-called long Agos are composed of four major domains (N, PAZ, MID and PIWI) and contribute to RN

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3be66bd03d24d2cf5ff56bbe4bca24e7
https://bib-pubdb1.desy.de/record/485697

Prokaryotic Argonaute from Archaeoglobus fulgidus interacts with DNA as a homodimer

Autor: Arunas Silanskas, Edvardas Golovinas, Giedrius Sasnauskas, Mindaugas Zaremba, Danielis Rutkauskas, Marija Jankunec, Elena Manakova

Publikováno v: Scientific reports, London : Nature, 2021, vol. 11, art. no. 4518, p. 1-14
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific reports 11(1), 4518 (2021). doi:10.1038/s41598-021-83889-4
Scientific Reports

Scientific reports 11(1), 4518 (2021). doi:10.1038/s41598-021-83889-4
Argonaute (Ago) proteins are found in all three domains of life. The best-characterized group is eukaryotic Argonautes (eAgos), which are the core of RNA interference. The bes

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af00b310d7d191c96583f63af590394
https://repository.vu.lt/VU:ELABAPDB103072966&prefLang=en_US