Zobrazeno 1 - 10
of 189
pro vyhledávání: '"Edus H Warren"'
Autor:
Cindy Y. Jiang, Lili Zhao, Michael D. Green, Shashidhar Ravishankar, Andrea M. H. Towlerton, Anthony J. Scott, Malini Raghavan, Matthew F. Cusick, Edus H. Warren, Nithya Ramnath
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Immune checkpoint inhibitors (ICI) are important treatment options for metastatic non-small cell lung cancer (mNSCLC). However, not all patients benefit from ICIs and can experience immune-related adverse events (irAEs). Limited understandin
Externí odkaz:
https://doaj.org/article/24bd8b92f8cc47e3ab5cc15afdd398f4
Autor:
Jeffrey Chou, Matthew P Fitzgibbon, Christie-Lynn L Mortales, Andrea M H Towlerton, Melissa P Upton, Raymond S Yeung, Martin W McIntosh, Edus H Warren
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e79874 (2013)
Xenografts of human colorectal cancer (CRC) in immune-deficient mice have great potential for accelerating the study of tumor biology and therapy. We evaluated xenografts established in NOD/scid/IL2Rγ-null mice from the primary or metastatic tumors
Externí odkaz:
https://doaj.org/article/5267379f85984cd8b5644a07f4b2d55a
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Tumor-associated endothelial cells (TECs) are crucial mediators of immune surveillance and immune escape in the tumor microenvironment (TME). TECs driven by angiogenic growth factors form an abnormal vasculature which deploys molecular machinery to s
Externí odkaz:
https://doaj.org/article/260e213f809045e5ad192a635db49c20
Autor:
David G. Coffey, Francesco Maura, Edgar Gonzalez-Kozlova, J. Javier Diaz-Mejia, Ping Luo, Yong Zhang, Yuexin Xu, Edus H. Warren, Travis Dawson, Brian Lee, Hui Xie, Eric Smith, Amanda Ciardiello, Hearn J. Cho, Adeeb Rahman, Seunghee Kim-Schulze, Benjamin Diamond, Alexander Lesokhin, Dickran Kazandjian, Trevor J. Pugh, Damian J. Green, Sacha Gnjatic, Ola Landgren
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The role of the immune microenvironment in maintaining disease remission in patients with multiple myeloma (MM) is not well understood. In this study, we comprehensively profile the immune system in patients with newly diagnosed MM receiving
Externí odkaz:
https://doaj.org/article/f009262e72e74d7eb9e4d2fcf98a1f75
Autor:
Chris P. Miller, Megan Fung, Carla A. Jaeger-Ruckstuhl, Yuexin Xu, Edus H. Warren, Shreeram Akilesh, Scott S. Tykodi
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 46, Iss , Pp 100948- (2023)
Metastatic renal cell carcinoma (RCC) remains an incurable disease for most patients highlighting an urgent need for new treatments. However, the preclinical investigation of new therapies is limited by traditional two-dimensional (2D) cultures which
Externí odkaz:
https://doaj.org/article/9a6a0ba591d64c2b98c9db933ac8344f
Autor:
Charlotte A. James, Yuexin Xu, Melissa S. Aguilar, Lichen Jing, Erik D. Layton, Martine Gilleron, Adriaan J. Minnaard, Thomas J. Scriba, Cheryl L. Day, Edus H. Warren, David M. Koelle, Chetan Seshadri
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
CD4 and CD8 co-receptors are routinely used to define distinct functional and phenotypic lineages of T cells. Here the authors show CD4 and CD8 also modulate the functional avidity of the CD1b-restricted response to mycobacterial lipid antigens
Externí odkaz:
https://doaj.org/article/5ffbba8ac40b4631bfdd4ca36548cb97
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 17, Iss 7, Pp 1882-1896 (2021)
In renal-cell carcinoma (RCC), tumor-reactive T-cell responses can occur spontaneously or in response to systemic immunotherapy with cytokines and immune checkpoint inhibitors. Cancer vaccines and engineered T-cell therapies are designed to selective
Externí odkaz:
https://doaj.org/article/fdeb72bf1a044f61940f92e772545845
Autor:
Ryan C. Lynch, Stefan Alig, Chaitra S. Ujjani, Christina Poh, Edus H. Warren, Stephen D. Smith, Mazyar Shadman, Andrei Shustov, Brian Till, Vikram M. Raghunathan, Yolanda Tseng, Hilary Coye, Megan Shelby, Susan Ottemiller, Sarith Keo, Kaitlin Verni, Hongyan Du, Jackie Vandermeer, Ashley Gaston, Heather Rasmussen, Avanti Gulhane, Delphine L. Chen, Paul Martin, Edmond Marzbani, Jenna Voutsinas, Ash A. Alizadeh, Ajay K. Gopal
Publikováno v:
HemaSphere, Vol 6, Pp 26-27 (2022)
Externí odkaz:
https://doaj.org/article/1dca62dfced740de83e0d17bd541a259
Autor:
Andrea M. H. Towlerton, Shashidhar Ravishankar, David G. Coffey, Camille E. Puronen, Edus H. Warren
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Long-term antiretroviral therapy (ART) in people living with HIV (PLHIV) is associated with sustained increases in CD4+ T-cell count, but its effect on the peripheral blood T-cell repertoire has not been comprehensively evaluated. In this study, we p
Externí odkaz:
https://doaj.org/article/a9febdcf9fc74b49aee6ef8069050e44
Autor:
Christopher P. Miller, Farinaz Shokri, Shreeram Akilesh, Yuexin Xu, Edus H. Warren, Scott S. Tykodi, Maria Tretiakova
Publikováno v:
Applied Immunohistochemistry & Molecular Morphology. 31:135-144
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d395e65229c3f6b225c0e62ff299c54
https://doi.org/10.1097/pai.0000000000001101
https://doi.org/10.1097/pai.0000000000001101