Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Edurne, Elizalde"'
Autor:
Ignacio Melero, Maria C Ochoa, Carmen Molina, Sandra Sanchez‐Gregorio, Saray Garasa, Carlos Luri‐Rey, Sandra Hervas‐Stubbs, Noelia Casares, Edurne Elizalde, Gabriel Gomis, Assunta Cirella, Pedro Berraondo, Alvaro Teijeira, Maite Alvarez
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 11, Pp 1-16 (2023)
Abstract NK‐cell reactivity against cancer is conceivably suppressed in the tumor microenvironment by the interaction of the inhibitory receptor NKG2A with the non‐classical MHC‐I molecules HLA‐E in humans or Qa‐1b in mice. We found that in
Externí odkaz:
https://doaj.org/article/dad7d8e3e32044ab82bb7ccfc15b4a39
Autor:
Sandra Hervás-Stubbs, Julián Pardo, Gloria González-Aseguinolaza, Noelia Casares, Iratxe Uranga-Murillo, Juan Lasarte, Uxua Mancheno, Enrique Conde, Enric Vercher, Marta Soria-Castellano, Jesús Suarez-Olmos, Edurne Elizalde, M Luis Rodriguez, Estefanía Rodríguez-García, Mirja Hommel, Gorka Alkorta
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Externí odkaz:
https://doaj.org/article/d555a98505d44ae688231f35b94f7fd2
Autor:
Enrique Conde, Noelia Casares, Uxua Mancheño, Edurne Elizalde, Enric Vercher, Roberto Capozzi, Eva Santamaria, Juan R. Rodriguez-Madoz, Felipe Prosper, Juan J. Lasarte, Teresa Lozano, Sandra Hervas-Stubbs
Publikováno v:
Molecular Therapy. 31:48-65
Regulatory T cells overwhelm conventional T cells in the tumor microenvironment (TME) thanks to a FOXP3-driven metabolic program that allows them to engage different metabolic pathways. Using a melanoma model of adoptive T cell therapy (ACT), we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb86c315f8c335b7cc9e340499b1e61
https://doi.org/10.1016/j.ymthe.2022.08.017
https://doi.org/10.1016/j.ymthe.2022.08.017
Autor:
Sandra Hervas-Stubbs, Juan Jose Lasarte, Pablo Sarobe, Enrique Conde, Itziar Otano, Natalia Zubeldia, Diego Alignani, Edurne Elizalde, Uxua Mancheño, Jose-Ignacio Riezu-Boj, Noelia Casares, Teresa Lozano, Diego Salas-Benito, Sarita M. Fernandez-Poma
Supplementary Figures: (Fig. S1) Multi-parametric flow cytometric analysis of tumor-infiltrating T lymphocyte subsets from freshly excised MC38 tumors; (Fig. S2) Expression of co-inhibitory and co-stimulatory molecules over the course of tumor progre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e6eaea352525fd5b0df36c1dc00b14c
https://doi.org/10.1158/0008-5472.22413327.v1
https://doi.org/10.1158/0008-5472.22413327.v1
Autor:
Sandra Hervas-Stubbs, Juan Jose Lasarte, Pablo Sarobe, Enrique Conde, Itziar Otano, Natalia Zubeldia, Diego Alignani, Edurne Elizalde, Uxua Mancheño, Jose-Ignacio Riezu-Boj, Noelia Casares, Teresa Lozano, Diego Salas-Benito, Sarita M. Fernandez-Poma
Recent studies have found that tumor-infiltrating lymphocytes (TIL) expressing PD-1 can recognize autologous tumor cells, suggesting that cells derived from PD-1+ TILs can be used in adoptive T-cell therapy (ACT). However, no study thus far has evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::29e06d2b765f2eb2a9a8fb80cba925ad
https://doi.org/10.1158/0008-5472.c.6508686.v1
https://doi.org/10.1158/0008-5472.c.6508686.v1
Autor:
Sandra Hervas-Stubbs, Ibon Tamayo-Uria, Pablo Sarobe, Uxua Mancheño, Antonio González-Martín, Edurne Elizalde, José Manuel Aramendía, Juan C. Muruzabal, Mariano Ponz-Sarvise, Francisco Guillén-Grima, Juan José Lasarte, Julia Alcaide, Enrique Conde, David Garcia-Ros, Carlos E. de Andrea, Diego Salas-Benito, José Ángel Mínguez, Jose Amores-Tirado
Publikováno v:
British Journal of Cancer
Background Adoptive immunotherapy with tumour-infiltrating lymphocytes (TIL) may benefit from the use of selective markers, such as PD-1, for tumour-specific T-cell enrichment, and the identification of predictive factors that help identify those pat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8341aaeb56bee99355258a52e317e5a5
http://europepmc.org/articles/PMC7961070
http://europepmc.org/articles/PMC7961070
Autor:
Diego Salas-Benito, Enrique Conde, Ibon Tamayo-Uria, Uxua Mancheño, Edurne Elizalde, David Garcia-Ros, Jose M. Aramendia, Juan C. Muruzabal, Julia Alcaide, Francisco Guillen-Grima, Jose A. Minguez, Jose Amores-Tirado, Antonio Gonzalez-Martin, Pablo Sarobe, Juan J. Lasarte, Mariano Ponz-Sarvise, Carlos E. De Andrea, Sandra Hervas-Stubbs
Background: Adoptive immunotherapy with tumor-infiltrating lymphocytes (TIL) may benefit from the use of selective markers, such as programmed cell death protein 1 (PD-1), for tumor-specific T-cell enrichment, as well as predictive biomarkers that he
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a7ec119d7cf271d8c737de45bd71cc08
https://doi.org/10.21203/rs.3.rs-25670/v1
https://doi.org/10.21203/rs.3.rs-25670/v1
Autor:
Enric Vercher, Mirja Hommel, Uxua Mancheño, Estefania Rodríguez-Garcia, Gloria González-Aseguinolaza, Ignacio Melero, Edurne Elizalde, Juan José Lasarte, Enrique Conde, Jesús Suarez-Olmos, Javier Glez-Vaz, Noelia Casares, Julián Pardo, Marta Soria-Castellano, M Luis Rodriguez, Gorka Alkorta, Sandra Hervas-Stubbs, Iratxe Uranga-Murillo
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 11 (2021)
BackgroundTarget antigen (Ag) loss has emerged as a major cause of relapse after chimeric antigen receptor T (CART)-cell therapy. We reasoned that the combination of CART cells, with the consequent tumor debulking and release of Ags, together with an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09b353eac8dd2bfe9be10766b27cf9cf
https://doi.org/10.1136/jitc-2021-003351
https://doi.org/10.1136/jitc-2021-003351
Autor:
José-Ignacio Riezu-Boj, Enrique Conde, Diego Salas-Benito, Sarita M. Fernandez-Poma, Diego Alignani, Uxua Mancheño, Teresa Lozano, Noelia Casares, Sandra Hervas-Stubbs, Natalia Zubeldia, Itziar Otano, Pablo Sarobe, Juan José Lasarte, Edurne Elizalde
Publikováno v:
Cancer Research. 77:3672-3684
Recent studies have found that tumor-infiltrating lymphocytes (TIL) expressing PD-1 can recognize autologous tumor cells, suggesting that cells derived from PD-1+ TILs can be used in adoptive T-cell therapy (ACT). However, no study thus far has evalu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d70a360052c47e986ce2732c0712af75
https://doi.org/10.1158/0008-5472.can-17-0236
https://doi.org/10.1158/0008-5472.can-17-0236
Autor:
Enric Vercher, Ibon Tamayo, Uxua Mancheño, Edurne Elizalde, Enrique Conde, David Reparaz, Juan J. Lasarte, Virginia Villar, Mercedes Iñarrairaegui, Bruno Sangro, Pablo Sarobe, Sandra Hervás-Stubbs
Publikováno v:
Journal of Hepatology. 73:S39-S40
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::628158005369c48fff5e7996f4f26c02
https://doi.org/10.1016/s0168-8278(20)30630-9
https://doi.org/10.1016/s0168-8278(20)30630-9