Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Edupuganti V.S. Raghu Ram"'
Publikováno v:
Genes & Development. 23:2793-2798
Embryonic stem (ES) cells possess a globally open, decondensed chromatin structure that, together with trans-acting factors, supports transcriptional competence of developmentally regulated genes. However, our understanding of the mechanisms that est
Autor:
Coralie Spiegelhalter, André Eid, Ana Bošković, Maria-Elena Torres-Padilla, Takashi Ishiuchi, Julien Pontabry, Edupuganti V.S. Raghu Ram, Eran Meshorer
Publikováno v:
Genes & Development
The fusion of the gametes upon fertilization results in the formation of a totipotent cell. Embryonic chromatin is expected to be able to support a large degree of plasticity. However, whether this plasticity relies on a particular conformation of th
Autor:
Alan J. Mears, Ilya Ioshikhes, David J. Picketts, Romit Majumder, Valerie A. Wallace, Rashmi Kothary, Danton Ivanochko, Erin A. Bassett, Juraj Kokavec, Matías Alvarez-Saavedra, Arthur I. Skoultchi, Matthew A. M. Todd, Keqin Yan, Pamela S. Lagali, Michael S. Huh, Tomas Stopka, Nicholas Tokarew, Edupuganti V.S. Raghu Ram, Eran Meshorer, Doo Yang, Emile Hashem, Yves De Repentigny, Chelsea P. Corcoran
Publikováno v:
Nature Communications
Chromatin compaction mediates progenitor to post-mitotic cell transitions and modulates gene expression programs, yet the mechanisms are poorly defined. Snf2h and Snf2l are ATP-dependent chromatin remodelling proteins that assemble, reposition and sp
Autor:
Edupuganti V.S. Raghu Ram, Eran Meshorer, Malka Nissim-Rafinia, Arigela Harikumar, Prim B. Singh, Siu Kwan Sze, Emmanuelle Supper, Jan-Philipp Mallm, Kae Hwan Sim, Karsten Rippe, Yair Aaronson, Anna Mattout, Susan M. Gasser, Badi Sri Sailaja
Publikováno v:
Genome Biology
Background Pluripotent embryonic stem cells (ESCs) have the unique ability to differentiate into every cell type and to self-renew. These characteristics correlate with a distinct nuclear architecture, epigenetic signatures enriched for active chroma