Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Eduardo Silva-Pavez"'
Autor:
Cristopher Almarza, Karla Villalobos-Nova, María A. Toro, Manuel González, Ignacio Niechi, David A. Brown‑Brown, Rodrigo A. López-Muñoz, Eduardo Silva-Pavez, Belén Gaete-Ramírez, Manuel Varas-Godoy, Verónica A. Burzio, Lilian Jara, Francisco Aguayo, Julio C. Tapia
Publikováno v:
Biological Research, Vol 57, Iss 1, Pp 1-12 (2024)
Abstract Background Lung cancer constitutes the leading cause of cancer mortality. High levels of endothelin-1 (ET-1), its cognate receptor ETAR and its activating enzyme, the endothelin-converting enzyme-1 (ECE-1), have been reported in several canc
Externí odkaz:
https://doaj.org/article/0cf4339a416b4966826e5c5eb699c312
Autor:
Eduardo Silva-Pavez, Elizabeth Mendoza, Pablo Morgado-Cáceres, Ulises Ahumada-Castro, Galdo Bustos, Matías Kangme-Encalada, Amaia Lopez de Arbina, Andrea Puebla-Huerta, Felipe Muñoz, Lucas Cereceda, Manuel Varas-Godoy, Yessia Hidalgo, J. Cesar Cardenas
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Increasing evidence supports the hypothesis that cancer progression is under mitochondrial control. Mitochondrial fission plays a pivotal role in the maintenance of cancer cell homeostasis. The inhibition of DRP1, the main regulator of mitoc
Externí odkaz:
https://doaj.org/article/17c5a6ac01104de481f2eaf100eee68f
Autor:
Francisco Rodas, Jetzabel A. Vidal-Vidal, Daniela Herrera, David A. Brown-Brown, Diego Vera, Joaquín Veliz, Pilar Püschel, José I. Erices, Verónica Sánchez Hinojosa, Julio C. Tapia, Eduardo Silva-Pavez, Claudia Quezada-Monrás, Pablo Mendoza-Soto, Flavio Salazar-Onfray, Cristian Carrasco, Ignacio Niechi
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-13 (2023)
Abstract Background Gallbladder cancer (GBC) is a prevalent and deadly biliary tract carcinoma, often diagnosed at advanced stages with limited treatment options. The 5-year survival rate varies widely from 4 to 60%, mainly due to differences in dise
Externí odkaz:
https://doaj.org/article/dbab4179d4a748d7bef2277a241ba50f
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2024)
Introduction: An active role of platelets in the progression of triple-negative breast cancer (TNBC) cells has been described. Even the role of platelet-derived extracellular vesicles on the migration of MDA-MB-231 cells has been reported. Interestin
Externí odkaz:
https://doaj.org/article/9f61b3aeebfc49418cc6377f4de5003f
Autor:
Ulises Ahumada-Castro, Galdo Bustos, Eduardo Silva-Pavez, Andrea Puebla-Huerta, Alenka Lovy, César Cárdenas
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
In the last few years, metabolism has been shown to be controlled by cross-organelle communication. The relationship between the endoplasmic reticulum and mitochondria/lysosomes is the most studied; here, inositol 1,4,5-triphosphate (IP3) receptor (I
Externí odkaz:
https://doaj.org/article/b70527f940a24b41b11e74605904d11d
Publikováno v:
Molecular & Cellular Oncology, Vol 8, Iss 1 (2021)
The inositol 1,4,5-triphosphate receptor (InsP3R)-mediated calcium (Ca2+) transfer to mitochondria is important to maintain mitochondrial respiration and bioenergetics in normal and cancer cells, even though cancer cells have defective oxidative phos
Externí odkaz:
https://doaj.org/article/b67169bc7cc04f7f849a894ad6e05bc4
Autor:
Pablo Pérez-Moreno, Camila Quezada-Meza, Cristopher Chavez-Almarza, Ignacio Niechi, Eduardo Silva-Pavez, César Trigo-Hidalgo, Francisco Aguayo, Lilian Jara, Albano Cáceres-Verschae, Manuel Varas-Godoy, Víctor M. Díaz, Antonio García de Herreros, Verónica A. Burzio, Julio C. Tapia
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Endothelin-converting enzyme-1 (ECE1) activates the endothelin-1 peptide, which upregulates pathways that are related to diverse hallmarks of cancer. ECE1 is expressed as four isoforms differing in their N-terminal domains. Protein kinase CK2 phospho
Externí odkaz:
https://doaj.org/article/c5d15211b6f741cbb97cf35bac2c6ec9
Autor:
Eduardo Silva-Pavez, Julio C. Tapia
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Protein kinase CK2 (formerly known as casein kinase 2) is abnormally elevated in many cancers. This may increase tumor aggressiveness through CK2-dependent phosphorylation of key proteins in several signaling pathways. In this work, we have compiled
Externí odkaz:
https://doaj.org/article/ab58af00eb984dcba8cda8c4ecf8ce3b
Publikováno v:
Environmental Research. :116201
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a8f79bd03e8c1589a13bd259fef1c300
https://doi.org/10.1016/j.envres.2023.116201
https://doi.org/10.1016/j.envres.2023.116201
Autor:
Galdo, Bustos, Ulises, Ahumada-Castro, Eduardo, Silva-Pavez, Andrea, Puebla, Alenka, Lovy, J, Cesar Cardenas
Publikováno v:
International review of cell and molecular biology. 363
Cancer is a leading cause of death worldwide. All major tumor suppressors and oncogenes are now recognized to have fundamental connections with metabolic pathways. A hallmark feature of cancer cells is a reprogramming of their metabolism even when nu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7db3ed4d7bfb52252b1affa73137cab1
https://pubmed.ncbi.nlm.nih.gov/34392932
https://pubmed.ncbi.nlm.nih.gov/34392932