Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Eduardo Setti"'
Autor:
Brian T. Campbell, Arup K. Ghose, Helen Hua, Ronald R. Nepomuceno, Joyce James, Mark A. Ator, Brian Struss, Torsten Herbertz, Ruwanthi N. Gunawardane, Mark W. Holladay, Michael Williams, Darren E. Insko, Eduardo Setti, Susan Jones-Bolin, Ianina Valenta, Julius L. Apuy, Sunny Abraham, Martin W. Rowbottom, Michael F. Gardner, Robert C. Armstrong, Merryl D. Cramer, Michael Gibney, Lan Tran, Kelly G. Sprankle, Maiko Ezawa, Bruce D. Dorsey, Raffaella Faraoni, Dana Gitnick, Shripad Bhagwat, Qi Chao, Andiliy G. Lai, Bruce Ruggeri
Publikováno v:
Journal of medicinal chemistry. 55(3)
The Ras/RAF/MEK/ERK mitogen-activated protein kinase (MAPK) signaling pathway plays a central role in the regulation of cell growth, differentiation, and survival. Expression of mutant BRAF(V600E) results in constitutive activation of the MAPK pathwa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1b9a154f5ee6c6a53767b6f49b9b014
https://pubmed.ncbi.nlm.nih.gov/22168626
https://pubmed.ncbi.nlm.nih.gov/22168626
Autor:
Michael Williams, Kelly G. Sprankle, Mark W. Holladay, Shripad Bhagwat, Qi Chao, Raffaella Faraoni, Dana Gitnick, Lan Tran, Joyce James, Sunny Abraham, Andiliy G. Lai, Brian T. Campbell, Martin W. Rowbottom, Ruwanthi N. Gunawardane, Bruce R. Ruggeri, Michael F. Gardner, Robert C. Armstrong, Mark A. Ator, Bruce D. Dorsey, Eduardo Setti, Merryl D. Cramer
Publikováno v:
Bioorganicmedicinal chemistry letters. 21(18)
Aryl phenyl ureas with a 4-quinazolinoxy substituent at the meta-position of the phenyl ring are potent inhibitors of mutant and wild type BRAF kinase. Compound 7 (1-(5-tert-butylisoxazol-3-yl)-3-(3-(6,7-dimethoxyquinazolin-4-yloxy)phenyl)urea hydroc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ce7e41c9edb64b7e28a4e6f99bd14a
https://pubmed.ncbi.nlm.nih.gov/21807507
https://pubmed.ncbi.nlm.nih.gov/21807507
Autor:
Andrada, Lidia Estefania, Lunad Rocha, Jimena, José Rosa, Ramiro, Cerviño, Santiago, Eduardo Setti, Walter, Daniel Leguiza, Hector, Beatriz Medina, Roxana, Patricia Chagra, Elsa
Publikováno v:
Revista Acadêmica: Ciência Animal; 2019 Supplement, Vol. 17, p179-179, 1p