A Novel Protocol for the Synthesis of 1,2,4-Oxadiazoles Active against Trypanosomatids and Drug-Resistant Leukemia Cell Lines

Autor: Paulo Pitasse-Santos, Eduardo Salustiano, Raynná Bittencourt Pena, Otávio Augusto Chaves, Leonardo Marques da Fonseca, Kelli Monteiro da Costa, Carlos Antônio do Nascimento Santos, Jhenifer Santos Dos Reis, Marcos André Rodrigues da Costa Santos, Jose Osvaldo Previato, Lucia Mendonça Previato, Leonardo Freire-de-Lima, Nelilma Correia Romeiro, Lúcia Helena Pinto-da-Silva, Célio G. Freire-de-Lima, Débora Decotè-Ricardo, Marco Edilson Freire-de-Lima

Publikováno v: Tropical Medicine and Infectious Disease, Vol 7, Iss 12, p 403 (2022)

Cancer and parasitic diseases, such as leishmaniasis and Chagas disease, share similarities that allow the co-development of new antiproliferative agents as a strategy to quickly track the discovery of new drugs. This strategy is especially interesti

Externí odkaz: https://doaj.org/article/4cb9d0829caf4b10b3b7a55a9b082f65

(±)-3,4-Dihydroxy-8,9-methylenedioxypterocarpan and derivatives: Cytotoxic effect on human leukemia cell lines

Autor: Carolina Pereira Castro, Alcides J. M. da Silva, Eduardo Salustiano Jesus Dos Santos, Paulo R. R. Costa, Chaquip D. Netto, Vivian M. Rumjanek

Publikováno v: European Journal of Medicinal Chemistry. 44:920-925

Naturally occurring pterocarpans 1a , b , pterocarpan 1c , isoflavane 2 and ortho -quinone 3 were synthesized in the racemic form and their cytotoxic effect was evaluated on the human leukemia cell lines K562 (resistant to oxidative stress), Lucena-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::793a55627e0fcf2f9604c89a8592c349
https://doi.org/10.1016/j.ejmech.2008.01.027

'Encrucijadas. El Juego de su Vida': Desarrollo de Herramienta Lúdica en la Prevención del Cáncer

Autor: Maia, Tainá, Machado, Gabriel de Oliveira Cardoso, Santos, Eduardo Salustiano Jesus dos, Verjovsky, Marina, Villela, Carolina, Jurberg, Claudia

Publikováno v: Revista Brasileira de Cancerologia; Vol. 59 No. 2 (2013): Apr./May/June; 219-227
Revista Brasileira de Cancerologia; Vol. 59 Núm. 2 (2013): abr./mayo/jun.; 219-227
Revista Brasileira de Cancerologia; v. 59 n. 2 (2013): abr./maio/jun. ; 219-227
Revista Brasileira de Cancerologia
Instituto Nacional de Câncer José Alencar Gomes da Silva (INCA)
instacron:INCA

Introduction: According to the National Cancer Institute José Alencar Gomes da Silva, about 80% of cancers are related to the environment. Annually applied researches performed by the Brazilian Institute for Geography and Statistics, across the enti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::c4dd65e1c2ee11c1c9de34b279093d15
https://rbc.inca.gov.br/index.php/revista/article/view/527

Isolamento e estudo da intera??o da mangiferina e derivados sint?ticos com albumina s?rica humana

Autor: Pinto, Douglas Chaves de Alc?ntara

Publikováno v: Biblioteca Digital de Teses e Dissertações da UFRRJ
Universidade Federal Rural do Rio de Janeiro (UFRRJ)
instacron:UFRRJ

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3056::bdc375fd81c597ba054fa6aea0313559
https://tede.ufrrj.br/jspui/handle/jspui/4444