Výsledky vyhledávání - "Eduardo Roggero"

Akademický článek

Trypanosoma cruzi Infection through the Oral Route Promotes a Severe Infection in Mice: New Disease Form from an Old Infection?

Autor: Juliana Barreto-de-Albuquerque, Danielle Silva-dos-Santos, Ana Rosa Pérez, Luiz Ricardo Berbert, Eliane de Santana-van-Vliet, Désio Aurélio Farias-de-Oliveira, Otacilio C Moreira, Eduardo Roggero, Carla Eponina de Carvalho-Pinto, José Jurberg, Vinícius Cotta-de-Almeida, Oscar Bottasso, Wilson Savino, Juliana de Meis

Publikováno v: PLoS Neglected Tropical Diseases, Vol 9, Iss 6, p e0003849 (2015)

Oral transmission of Chagas disease has been documented in Latin American countries. Nevertheless, significant studies on the pathophysiology of this form of infection are largely lacking. The few studies investigating oral route infection disregard

Externí odkaz: https://doaj.org/article/52030d6eae1743809072427a973ac410

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Akademický článek

Tumor necrosis factor-α regulates glucocorticoid synthesis in the adrenal glands of Trypanosoma cruzi acutely-infected mice. the role of TNF-R1.

Autor: Silvina R Villar, M Teresa Ronco, Rodrigo Fernández Bussy, Eduardo Roggero, Ailin Lepletier, Romina Manarin, Wilson Savino, Ana Rosa Pérez, Oscar Bottasso

Publikováno v: PLoS ONE, Vol 8, Iss 5, p e63814 (2013)

Adrenal steroidogenesis is under a complex regulation involving extrinsic and intrinsic adrenal factors. TNF-α is an inflammatory cytokine produced in response to tissue injury and several other stimuli. We have previously demonstrated that TNF-R1 k

Externí odkaz: https://doaj.org/article/119d6458d4344ebaae9beccc086a2521

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Glucocorticoids and sympathetic neurotransmitters modulate the acute immune response toTrypanosoma cruzi

Autor: Johannes Wildmann, Eduardo Roggero, Hugo O. Besedovsky, Adriana del Rey

Publikováno v: Annals of the New York Academy of Sciences. 1437:83-93

Evidence suggests that natural and adaptive immune responses can trigger neuroendocrine responses. Here, we discuss changes in the activity of the hypothalamus-pituitary-adrenal axis and in autonomic nerves, predominantly of the sympathetic nervous s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::505bd477f89707b572c4fcda277f1cf4
https://doi.org/10.1111/nyas.13946

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Putative Biomarkers of Response to Treatment in Breast Cancer Patients: A Pilot Assay

Autor: Carlos M. Alasino, Eduardo Roggero, Viviana R. Rozados, Ana Lía Nocito, María J. Rico, O. Graciela Scharovsky, Cintia Herrera, Herman A. Perroud, Stella Maris Pezzotto

Publikováno v: Cancer Investigation. 35:377-385

Identifying tumor biomarkers associated with clinical behavior in breast cancer patients may allow higher accuracy in the selection of treatment. Different types of cells were determined in the primary tumors of stage I, II, and III of breast cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50f665137dada0bfe57489058b7e5a7f
https://doi.org/10.1080/07357907.2017.1309545

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Glucocorticoids and sympathetic neurotransmitters modulate the acute immune response to Trypanosoma cruzi

Autor: Eduardo, Roggero, Adriana, Del Rey, Johannes, Wildmann, Hugo, Besedovsky

Publikováno v: Annals of the New York Academy of Sciences. 1437(1)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::143d3645899cfe8867832c68cf7e51a6
https://pubmed.ncbi.nlm.nih.gov/30088661

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Disruption of tumor necrosis factor alpha receptor 1 signaling accelerates NAFLD progression in mice upon a high-fat diet

Autor: A.S. Arboatti, Cristina E. Carnovale, Juan A. Monti, María Paula Ceballos, Ariel D. Quiroga, Paloma Martín-Sanz, M.G. Sedlmeier, María Teresa Ronco, Daniel E. Francés, Eduardo Roggero, Omar Motiño, Flavia Lambertucci, Gerardo B. Pisani, Silvina R. Villar, María de Luján Alvarez

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Digital.CSIC. Repositorio Institucional del CSIC
instname

Obesity is accompanied by a low-grade inflammation state, characterized by increased proinflammatory cytokines levels such as tumor necrosis factor alpha (TNFα) and interleukin-1 beta (IL-1β). In this regard, there exists a lack of studies in hepat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcdcc388e2877340d74d646f05705bb6
http://hdl.handle.net/10261/188143

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Efficacy of a trans-sialidase-ISCOMATRIX subunit vaccine candidate to protect against experimental Chagas disease

Autor: Nico Callewaert, Silvina R. Villar, Iván Bontempi, Miguel Hernán Vicco, Paul Ameloot, Gabriel Cabrera, Florencia Belén González, Iván Sergio Marcipar, Eduardo Roggero, Ana Rosa Pérez

Publikováno v: Vaccine. 33:1274-1283

Recombinant protein vaccines are safe but elicit low immunological responses. The new generation of adjuvants is currently reversing this situation. Here, a new antigen–adjuvant combination for protection against experimental Chagas disease was ass

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5df5818c63f2f7b20ae1233b966435b6
https://doi.org/10.1016/j.vaccine.2015.01.044

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Death of adrenocortical cells during murine acute T. cruzi infection is not associated with TNF-R1 signaling but mostly with the type II pathway of Fas-mediated apoptosis

Autor: Flavia Lambertucci, Silvina R. Villar, Eduardo Roggero, Juliana de Meis, Oscar Bottasso, María Teresa Ronco, Florencia Belén González, Ana Rosa Pérez

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
RepHipUNR (UNR)
Universidad Nacional de Rosario
instacron:UNR

Earlier studies from our laboratory demonstrated that acute experimental Trypanosoma cruzi infection promotes an intense inflammation along with a sepsis-like dysregulated adrenal response characterized by normal levels of ACTH with raised glucocorti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e065653cee3a113c9f0d2dc19092d81
https://pubmed.ncbi.nlm.nih.gov/28666938

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Reciprocal influences between leptin and glucocorticoids during acute Trypanosoma cruzi infection

Autor: Ana Rosa Pérez, Eva Verónica Deschutter, Rodrigo Fernández Bussy, Florencia Belén González, Romina Manarin, Ana Paula Bonantini, Oscar Bottasso, Eduardo Roggero, Silvina R. Villar

Publikováno v: Medical Microbiology and Immunology. 202:339-352

Leptin and glucocorticoids (GCs) are involved in metabolic functions, thymic homeostasis and immune activity through complex interactions. We recently showed that C57BL/6 mice infected with Trypanosoma cruzi revealed a fatal disease associated with a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eb2d8e72c63236c16516e6679dfd5494
https://doi.org/10.1007/s00430-013-0294-1

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The sympathetic nervous system affects the susceptibility and course of Trypanosoma cruzi infection

Autor: Ana Rosa Pérez, Hugo O. Besedovsky, Johannes Wildmann, Adriana del Rey, Eduardo Roggero, Natalia Pollachini, Silvina Raquel Villar

Publikováno v: Brain, behavior, and immunity. 58

Trypanosoma cruzi (T. cruzi) is an intracellular parasite that causes Chagas’ disease, a major health problem in Latin America. Using a murine model of infection with this parasite, we have previously shown that corticosterone blood levels are mark

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb51f6744c18e10cc18415d17da1e5e4
https://pubmed.ncbi.nlm.nih.gov/27485039

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