Zobrazeno 1 - 10
of 87
pro vyhledávání: '"Eduardo Reátegui"'
Autor:
Jingjing Zhang, Xilal Y. Rima, Xinyu Wang, Luong T. H. Nguyen, Kristin Huntoon, Yifan Ma, Paola Loreto Palacio, Kim Truc Nguyen, Karunya Albert, Minh‐Dao Duong‐Thi, Nicole Walters, Kwang Joo Kwak, Min Jin Yoon, Hong Li, Jacob Doon‐Ralls, Colin L. Hisey, Daeyong Lee, Yifan Wang, Jonghoon Ha, Kelsey Scherler, Shannon Fallen, Inyoul Lee, Andre F. Palmer, Wen Jiang, Setty M. Magaña, Kai Wang, Betty Y. S. Kim, L. James Lee, Eduardo Reátegui
Publikováno v:
Journal of Extracellular Vesicles, Vol 12, Iss 11, Pp n/a-n/a (2023)
Abstract The molecular heterogeneity of extracellular vesicles (EVs) and the co‐isolation of physically similar particles, such as lipoproteins (LPs), confounds and limits the sensitivity of EV bulk biomarker characterization. Herein, we present a
Externí odkaz:
https://doaj.org/article/793a6051126e4fb6a8e9f5fa55384db3
Autor:
Luong T. H. Nguyen, Jingjing Zhang, Xilal Y. Rima, Xinyu Wang, Kwang Joo Kwak, Tamio Okimoto, Joseph Amann, Min Jin Yoon, Takehito Shukuya, Chi‐Ling Chiang, Nicole Walters, Yifan Ma, Donald Belcher, Hong Li, Andre F. Palmer, David P. Carbone, L. James Lee, Eduardo Reátegui
Publikováno v:
Journal of Extracellular Vesicles, Vol 11, Iss 9, Pp n/a-n/a (2022)
Abstract Conventional PD‐L1 immunohistochemical tissue biopsies only predict 20%–40% of non‐small cell lung cancer (NSCLC) patients that will respond positively to anti‐PD‐1/PD‐L1 immunotherapy. Herein, we present an immunogold biochip to
Externí odkaz:
https://doaj.org/article/146b93eb927b403f95099c23ef145b70
Autor:
Bogdan Mateescu, Jennifer C. Jones, Roger P. Alexander, Eric Alsop, Ji Yeong An, Mohammad Asghari, Alex Boomgarden, Laura Bouchareychas, Alfonso Cayota, Hsueh-Chia Chang, Al Charest, Daniel T. Chiu, Robert J. Coffey, Saumya Das, Peter De Hoff, Andrew deMello, Crislyn D’Souza-Schorey, David Elashoff, Kiarash R. Eliato, Jeffrey L. Franklin, David J. Galas, Mark B. Gerstein, Ionita H. Ghiran, David B. Go, Stephen Gould, Tristan R. Grogan, James N. Higginbotham, Florian Hladik, Tony Jun Huang, Xiaoye Huo, Elizabeth Hutchins, Dennis K. Jeppesen, Tijana Jovanovic-Talisman, Betty Y.S. Kim, Sung Kim, Kyoung-Mee Kim, Yong Kim, Robert R. Kitchen, Vaughan Knouse, Emily L. LaPlante, Carlito B. Lebrilla, L. James Lee, Kathleen M. Lennon, Guoping Li, Feng Li, Tieyi Li, Tao Liu, Zirui Liu, Adam L. Maddox, Kyle McCarthy, Bessie Meechoovet, Nalin Maniya, Yingchao Meng, Aleksandar Milosavljevic, Byoung-Hoon Min, Amber Morey, Martin Ng, John Nolan, Getulio P. De Oliveira Junior, Michael E. Paulaitis, Tuan Anh Phu, Robert L. Raffai, Eduardo Reátegui, Matthew E. Roth, David A. Routenberg, Joel Rozowsky, Joseph Rufo, Satyajyoti Senapati, Sigal Shachar, Himani Sharma, Anil K. Sood, Stavros Stavrakis, Alessandra Stürchler, Muneesh Tewari, Juan P. Tosar, Alexander K. Tucker-Schwartz, Andrey Turchinovich, Nedyalka Valkov, Kendall Van Keuren-Jensen, Kasey C. Vickers, Lucia Vojtech, Wyatt N. Vreeland, Ceming Wang, Kai Wang, ZeYu Wang, Joshua A. Welsh, Kenneth W. Witwer, David T.W. Wong, Jianping Xia, Ya-Hong Xie, Kaichun Yang, Mikołaj P. Zaborowski, Chenguang Zhang, Qin Zhang, Angela M. Zivkovic, Louise C. Laurent
Publikováno v:
iScience, Vol 25, Iss 8, Pp 104653- (2022)
Summary: The extracellular RNA communication consortium (ERCC) is an NIH-funded program aiming to promote the development of new technologies, resources, and knowledge about exRNAs and their carriers. After Phase 1 (2013–2018), Phase 2 of the progr
Externí odkaz:
https://doaj.org/article/d72ed055b3ab4740b73e722d85b82959
Autor:
Jingjing Zhang, Luong T. H. Nguyen, Richard Hickey, Nicole Walters, Xinyu Wang, Kwang Joo Kwak, L. James Lee, Andre F. Palmer, Eduardo Reátegui
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)
Abstract Extracellular vesicles (EVs) derived from tumor cells have the potential to provide a much-needed source of non-invasive molecular biomarkers for liquid biopsies. However, current methods for EV isolation have limited specificity towards tum
Externí odkaz:
https://doaj.org/article/1da76a5ccfd04a989da3fc36409bd677
Autor:
Eswar Shankar, Sridhar SNC, Xilal Y. Rima, Prem Kushwaha, Shiv Verma, Gautam K. Sarathy, Anagh kulkarni, Dharmaraja Allimuthu, Eduardo Reátegui, Sanjay Gupta, Bhuvaneswari Ramaswamy
Publikováno v:
Cancer Research. 83:P2-16
Objective: Triple Negative Breast Cancers (TNBC) are highly invasive and 46% of patients develop distant metastases, leading to higher mortality. Chemotherapy remains the most efficacious option, however, there is still a largely unmet need to identi
Autor:
Nicole Walters, Jingjing Zhang, Xilal Y. Rima, Luong T. H. Nguyen, Ronald N. Germain, Tim Lämmermann, Eduardo Reátegui
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils are known to be the first responders to infection or injury. However, as inflammation progresses, other leukocytes become increasingly important in inflammation propagation, tissue reconstruction, and inflammation resolution. In recent ye
Externí odkaz:
https://doaj.org/article/7ed7a5c99e9047818cbc591b4cef324a
Autor:
Shannon N Tessier, Lauren D Bookstaver, Cindy Angpraseuth, Cleo J Stannard, Beatriz Marques, Uyen K Ho, Alona Muzikansky, Berent Aldikacti, Eduardo Reátegui, Daniel C Rabe, Mehmet Toner, Shannon L Stott
Publikováno v:
PLoS ONE, Vol 16, Iss 5, p e0251290 (2021)
Extracellular vesicles (EVs) have emerged as promising candidates in biomarker discovery and diagnostics. Protected by the lipid bilayer, the molecular content of EVs in diverse biofluids are protected from RNases and proteases in the surrounding env
Externí odkaz:
https://doaj.org/article/37571d608dcc43d79e2f83e12ac8c324
Autor:
Eduardo Reátegui, Kristan E. van der Vos, Charles P. Lai, Mahnaz Zeinali, Nadia A. Atai, Berent Aldikacti, Frederick P. Floyd, Aimal H. Khankhel, Vishal Thapar, Fred H. Hochberg, Lecia V. Sequist, Brian V. Nahed, Bob S. Carter, Mehmet Toner, Leonora Balaj, David T. Ting, Xandra O. Breakefield, Shannon L. Stott
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Extracellular vesicles can carry many different types of biological cargo and have been investigated as a biomarker for cancer diagnosis. Here the authors develop a microfluidic platform for rapid and sensitive isolation of tumor-specific extracellul
Externí odkaz:
https://doaj.org/article/849c53b9683c4d739bdab8480afd929d
Autor:
Xilal Y. Rima, Jingjing Zhang, Luong T. H. Nguyen, Aaron Rajasuriyar, Min Jin Yoon, Chi-Ling Chiang, Nicole Walters, Kwang Joo Kwak, L. James Lee, Eduardo Reátegui
Publikováno v:
Lab Chip
Investigating cellular and vesicular heterogeneity in breast cancer remains a challenge, which encourages the development of controllable in vitro systems that mimic the tumor microenvironment. Although three-dimensional cell culture better recapitul
Autor:
Xilal Y. Rima, Gautham Sarathy, Lara Rizzotto, Anagh Kulkarni, Dario Palmieri, Meisam Naeimi Kararoudi, Eduardo Reátegui, Bhuvaneswari Ramaswamy, Eswar Shankar
Publikováno v:
Cancer Research. 83:332-332
Triple negative breast cancer (TNBC) cells overexpress enhancer of zeste homolog 2 (EZH2) the catalytic subunit of polycomb repressive complex 2 (PRC2). EZH2 is a potential driver of TNBC metastasis, and its high expression strongly associates with t