Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Eduardo Perez-Torres"'
Autor:
Emily M. Rocha, Gaynor A. Smith, Eric Park, Hongmei Cao, Eilish Brown, Melissa A. Hayes, Jonathan Beagan, Jesse R. McLean, Sarah C. Izen, Eduardo Perez-Torres, Penelope J. Hallett, Ole Isacson
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 495-503 (2015)
Diminished lysosomal function can lead to abnormal cellular accumulation of specific proteins, including α-synuclein, contributing to disease pathogenesis of vulnerable neurons in Parkinson's disease (PD) and related α-synucleinopathies. GBA1 encod
Externí odkaz:
https://doaj.org/article/2ef89fe7a22c4b478cadce9df032959e
Autor:
Eduardo Perez-Torres, James M. Schumacher, Teresia Osborn, Maria Sundberg, Michele A. Moore, Anna-Liisa Brownell, Arnar Astradsson, Ole Isacson, Oliver Cooper, Michela Deleidi, Penelope J. Hallett, Roger D. Spealman, Gaynor A. Smith
Publikováno v:
Cell Stem Cell. 16(3):269-274
SummaryAutologous transplantation of patient-specific induced pluripotent stem cell (iPSC)-derived neurons is a potential clinical approach for treatment of neurological disease. Preclinical demonstration of long-term efficacy, feasibility, and safet
Autor:
Gunnar Hargus, Adam S. Levy, Alexandra Blak, Elizabeth Marlow, Michela Deleidi, Eduardo Perez-Torres, Alyssa Yow, Ole Isacson, Kristen Lee, Teresia Osborn, Oliver Cooper
Publikováno v:
Molecular and Cellular Neuroscience. 45:258-266
The cardinal motor symptoms of Parkinson's disease (PD) are caused by the vulnerability to dysfunction and degeneration of ventral midbrain (VM) dopaminergic (DA) neurons. A major limitation for experimental studies of current ES/iPS cell differentia
Autor:
Óscar Chapa-Azuela, María J. Corona-Torres, Edwin A. Ayala-Moreno, Paola S. Arroyo-Paredes, Eduardo Pérez-Torres, Alejandro Rodríguez-Báez, Eduardo E. Montalvo-Javé
Publikováno v:
Cirugía y Cirujanos, Vol 91, Iss 2 (2023)
Antecedentes. El cáncer pancreático es la séptima causa de muerte en el mundo, siendo el adenocarcinoma ductal del páncreas la neoplasia más frecuente. La mitad de los pacientes que son diagnosticados presentan metástasis al momento del diagnó
Externí odkaz:
https://doaj.org/article/44e44c7814b74130ac7580d550e2c432
Autor:
Eilish Brown, Jonathan A. Beagan, Penelope J. Hallett, Gaynor A. Smith, Emily M. Rocha, Eric Park, Ole Isacson, Anne-Renee Graham, Sarah C. Izen, Jesse R. McLean, Melissa A. Hayes, Eduardo Perez-Torres, Hongmei Cao
Publikováno v:
Antioxidants & Redox Signaling
Aims: Loss-of-function mutations in GBA1, which cause the autosomal recessive lysosomal storage disease, Gaucher disease (GD), are also a key genetic risk factor for the α-synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy
Autor:
Jesse R. McLean, Hongmei Cao, Melissa A. Hayes, Eduardo Perez-Torres, Penelope J. Hallett, Ole Isacson, Emily M. Rocha, Sarah C. Izen, Eilish Brown, Eric Park, Gaynor A. Smith, Jonathan A. Beagan
Publikováno v:
Neurobiology of Disease, Vol 82, Iss, Pp 495-503 (2015)
Diminished lysosomal function can lead to abnormal cellular accumulation of specific proteins, including α-synuclein, contributing to disease pathogenesis of vulnerable neurons in Parkinson's disease (PD) and related α-synucleinopathies. GBA1 encod
Autor:
Owen A. Ross, Ole Isacson, Maria Sundberg, Joseph R. Mazzulli, Hyemyung Seo, Serge Przedborski, Houbo Jiang, Eduardo Perez-Torres, Li Chen, Leslie A. Scarffe, Lorraine N. Clark, Karen Marder, Grzegorz Opala, Christine Klein, Luis Carrillo-Reid, Jesse R. McLean, Virginia M.-Y. Lee, Oliver Cooper, Laura A. Volpicelli-Daley, Shaida A. Andrabi, Helle Bogetofte, Ryan J. Uitti, Tristan Lawson, Norma Romero, Jian Feng, Gunnar Hargus, Carol Moskowitz, Valina L. Dawson, Michela Deleidi, Dimitri Krainc, Cristina Guardia-Laguarta, Zhigao Huang, John J. Graziotto, Ted M. Dawson, D. James Surmeier, Zhong Xie, John Q. Trojanowski, Zbigniew K. Wszolek, Teresia Osborn
Publikováno v:
Science Translational Medicine. 4
Parkinson’s disease (PD) is a common neurodegenerative disorder caused by genetic and environmental factors that results in degeneration of the nigrostriatal dopaminergic pathway in the brain. We analyzed neural cells generated from induced pluripo
Autor:
María Andrea Peñaloza-Posada, Eduardo Pérez-Torres, José Luis Pérez-Hernández, Fátima Higuera-de la Tijera
Publikováno v:
Revista Médica del Hospital General de México, Vol 77, Iss 4, Pp 179-184 (2014)
Introduction: Variceal bleeding (VB) is a serious complication in cirrhotic patients. Hepatic pressure venous gradient (HPVG) is the gold standard to assess high risk of VB, but, this is not always available and is an invasive method. Therefore is ne
Externí odkaz:
https://doaj.org/article/0ff28271dde04f45b1423e4148cb4441
Autor:
Fátima Higuera-de la Tijera, Alfredo Israel Servín-Caamaño, Eduardo Pérez-Torres, Francisco Salas-Gordillo, Juan Miguel Abdo-Francis, José Luis Pérez-Hernández, David Kershenobich
Publikováno v:
Revista Médica del Hospital General de México, Vol 77, Iss 4, Pp 160-166 (2014)
Background: Severe alcoholic hepatitis (SAH) presents high early mortality-rate (90 days) and is related to several complications. The aim of this study was to evaluate the impact on early mortality-rate of developed complications in patients with SA
Externí odkaz:
https://doaj.org/article/83a22f4534914c82a843a396f7def406
Autor:
Azucena I. Casanova-Lara, Pilar A. Peniche-Moguel, José L. Pérez-Hernández, Eduardo Pérez-Torres, Galileo Escobedo González, Chantal J. Córdova-Gallardo
Publikováno v:
Revista Médica del Hospital General de México, Vol 77, Iss 4, Pp 173-178 (2014)
Background: Hepatic osteodystrophy is any bone disease in patients with chronic liver disease. To measure bone mineral density (BMD) T-score by bone densitometry (BD) is used, classifying the disease in osteopenia, osteoporosis and severe osteoporosi
Externí odkaz:
https://doaj.org/article/439d0b0d92414772aa4c359a308b8c24