Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Eduardo Perez-Torres"'
Autor:
Emily M. Rocha, Gaynor A. Smith, Eric Park, Hongmei Cao, Eilish Brown, Melissa A. Hayes, Jonathan Beagan, Jesse R. McLean, Sarah C. Izen, Eduardo Perez-Torres, Penelope J. Hallett, Ole Isacson
Publikováno v:
Neurobiology of Disease, Vol 82, Iss , Pp 495-503 (2015)
Diminished lysosomal function can lead to abnormal cellular accumulation of specific proteins, including α-synuclein, contributing to disease pathogenesis of vulnerable neurons in Parkinson's disease (PD) and related α-synucleinopathies. GBA1 encod
Externí odkaz:
https://doaj.org/article/2ef89fe7a22c4b478cadce9df032959e
Autor:
Eduardo Perez-Torres, James M. Schumacher, Teresia Osborn, Maria Sundberg, Michele A. Moore, Anna-Liisa Brownell, Arnar Astradsson, Ole Isacson, Oliver Cooper, Michela Deleidi, Penelope J. Hallett, Roger D. Spealman, Gaynor A. Smith
Publikováno v:
Cell Stem Cell. 16(3):269-274
SummaryAutologous transplantation of patient-specific induced pluripotent stem cell (iPSC)-derived neurons is a potential clinical approach for treatment of neurological disease. Preclinical demonstration of long-term efficacy, feasibility, and safet
Autor:
Gunnar Hargus, Adam S. Levy, Alexandra Blak, Elizabeth Marlow, Michela Deleidi, Eduardo Perez-Torres, Alyssa Yow, Ole Isacson, Kristen Lee, Teresia Osborn, Oliver Cooper
Publikováno v:
Molecular and Cellular Neuroscience. 45:258-266
The cardinal motor symptoms of Parkinson's disease (PD) are caused by the vulnerability to dysfunction and degeneration of ventral midbrain (VM) dopaminergic (DA) neurons. A major limitation for experimental studies of current ES/iPS cell differentia
Autor:
Eilish Brown, Jonathan A. Beagan, Penelope J. Hallett, Gaynor A. Smith, Emily M. Rocha, Eric Park, Ole Isacson, Anne-Renee Graham, Sarah C. Izen, Jesse R. McLean, Melissa A. Hayes, Eduardo Perez-Torres, Hongmei Cao
Publikováno v:
Antioxidants & Redox Signaling
Aims: Loss-of-function mutations in GBA1, which cause the autosomal recessive lysosomal storage disease, Gaucher disease (GD), are also a key genetic risk factor for the α-synucleinopathies, including Parkinson's disease (PD) and dementia with Lewy
Autor:
Jesse R. McLean, Hongmei Cao, Melissa A. Hayes, Eduardo Perez-Torres, Penelope J. Hallett, Ole Isacson, Emily M. Rocha, Sarah C. Izen, Eilish Brown, Eric Park, Gaynor A. Smith, Jonathan A. Beagan
Publikováno v:
Neurobiology of Disease, Vol 82, Iss, Pp 495-503 (2015)
Diminished lysosomal function can lead to abnormal cellular accumulation of specific proteins, including α-synuclein, contributing to disease pathogenesis of vulnerable neurons in Parkinson's disease (PD) and related α-synucleinopathies. GBA1 encod
Autor:
Owen A. Ross, Ole Isacson, Maria Sundberg, Joseph R. Mazzulli, Hyemyung Seo, Serge Przedborski, Houbo Jiang, Eduardo Perez-Torres, Li Chen, Leslie A. Scarffe, Lorraine N. Clark, Karen Marder, Grzegorz Opala, Christine Klein, Luis Carrillo-Reid, Jesse R. McLean, Virginia M.-Y. Lee, Oliver Cooper, Laura A. Volpicelli-Daley, Shaida A. Andrabi, Helle Bogetofte, Ryan J. Uitti, Tristan Lawson, Norma Romero, Jian Feng, Gunnar Hargus, Carol Moskowitz, Valina L. Dawson, Michela Deleidi, Dimitri Krainc, Cristina Guardia-Laguarta, Zhigao Huang, John J. Graziotto, Ted M. Dawson, D. James Surmeier, Zhong Xie, John Q. Trojanowski, Zbigniew K. Wszolek, Teresia Osborn
Publikováno v:
Science Translational Medicine. 4
Parkinson’s disease (PD) is a common neurodegenerative disorder caused by genetic and environmental factors that results in degeneration of the nigrostriatal dopaminergic pathway in the brain. We analyzed neural cells generated from induced pluripo
Publikováno v:
Medical Devices & Surgical Technology Week; 6/25/2023, p1243-1243, 1p
Autor:
Sundberg, Maria, Bogetofte, Helle, Lawson, Tristan, Jansson, Johan, Smith, Gaynor, Astradsson, Arnar, Moore, Michele, Osborn, Teresia, Cooper, Oliver, Spealman, Roger, Hallett, Penelope, Isacson, Ole
Publikováno v:
Stem Cells; Aug2013, Vol. 31 Issue 8, p1548-1562, 15p
Autor:
Bogard, Sergio
Esta obra, desde el título, exhibe la naturaleza teórica que lo sustenta. Ni solo el significado, como mera intuición, ni la gramática per se, como un conjunto de reglas carentes de sustancia. Sí, en cambio, su articulación regulaa con la final
Autor:
Antonio Camiro Zúñiga, María Fernanda Parada Pérez, Vanessa Giselle Peschard Rodríguez, Carlos Vera Lara
Atención Primaria en Salud es la respuesta a la necesidad real, inmediata y cotidiana de un acceso rápido a información relevante y basada en evidencias sobre cómo se debe actuar en el primer nivel de atención. Es una fuente precisa de la inform