Zobrazeno 1 - 10
of 158
pro vyhledávání: '"Eduardo N Chini"'
Autor:
Antoine de Zélicourt, Abdallah Fayssoil, Mbarka Dakouane‐Giudicelli, Isley De Jesus, Ahmed Karoui, Faouzi Zarrouki, Florence Lefebvre, Arnaud Mansart, Jean‐Marie Launay, Jerome Piquereau, Mariana G Tarragó, Marcel Bonay, Anne Forand, Sophie Moog, France Piétri‐Rouxel, Elise Brisebard, Claudia C S Chini, Sonu Kashyap, Matthew J Fogarty, Gary C Sieck, Mathias Mericskay, Eduardo N Chini, Ana Maria Gomez, José‐Manuel Cancela, Sabine de la Porte
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 5, Pp 1-23 (2022)
Abstract Duchenne muscular dystrophy (DMD) is characterized by progressive muscle degeneration. Two important deleterious features are a Ca2+ dysregulation linked to Ca2+ influxes associated with ryanodine receptor hyperactivation, and a muscular nic
Externí odkaz:
https://doaj.org/article/ff8aa5831114408f802cc62d7a45fce4
Autor:
Raffaella Tulino, Agnesska C Benjamin, Nelly Jolinon, Donna L Smith, Eduardo N Chini, Alisia Carnemolla, Gillian P Bates
Publikováno v:
PLoS ONE, Vol 11, Iss 2, p e0150682 (2016)
[This corrects the article DOI: 10.1371/journal.pone.0145425.].
Externí odkaz:
https://doaj.org/article/243117c9159c4daaba9f9a69f9732654
Autor:
Raffaella Tulino, Agnesska C Benjamin, Nelly Jolinon, Donna L Smith, Eduardo N Chini, Alisia Carnemolla, Gillian P Bates
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0145425 (2016)
Huntington's disease (HD) is a neurodegenerative disorder for which there are no disease-modifying treatments. SIRT1 is a NAD+-dependent protein deacetylase that is implicated in maintaining neuronal health during development, differentiation and age
Externí odkaz:
https://doaj.org/article/fa4ad6c77f364fdf81ee63cfbb192c31
Autor:
Bo Shi, Asif Amin, Pranjali Dalvi, Wenxia Wang, Nicholas Lukacs, Li Kai, Paul Cheresh, Thais R. Peclat, Claudia C. Chini, Eduardo N. Chini, Wim van Schooten, John Varga
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-10 (2023)
Abstract The functionally pleiotropic ectoenzyme CD38 is a glycohydrolase widely expressed on immune and non-hematopoietic cells. By converting NAD+ to ADP-ribose and nicotinamide, CD38 governs organismal NAD+ homeostasis and the activity of NAD+-dep
Externí odkaz:
https://doaj.org/article/ce4eb7e544ce4488b97c57479f2f6806
Autor:
Colleen M Novak, Carlos Escande, Susan M Gerber, Eduardo N Chini, Minzhi Zhang, Steven L Britton, Lauren G Koch, James A Levine
Publikováno v:
PLoS ONE, Vol 4, Iss 6, p e5869 (2009)
Some people remain lean despite pressure to gain weight. Lean people tend to have high daily activity levels, but the source of this increased activity is unknown. We found that leanness cannot be accounted for by increased weight-corrected food inta
Externí odkaz:
https://doaj.org/article/6e3e6abfc82d4d55a82b9f8635c281b9
Autor:
Xiaoyu Ma, Yingyi Zhang, Yuanyuan Zhang, Xu Zhang, Yan Huang, Kai He, Chuan Chen, Jielu Hao, Debiao Zhao, Nathan K. LeBrasseur, James L. Kirkland, Eduardo N. Chini, Qing Wei, Kun Ling, Jinghua Hu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Exposure to irreparable stresses induces transient ciliogenesis, enabling communication with PML-NBs via a FBF1 pathway to trigger senescence in mammalian cells. Fbf1 ablation reduces senescence and associated health decline in mice, highlighting cil
Externí odkaz:
https://doaj.org/article/880ce8033dc74d578533b640039e7438
Autor:
Ashita Jain, Diego Casanova, Alejandra Valdivia Padilla, Angelica Paniagua Bojorges, Sivareddy Kotla, Kyung Ae Ko, Venkata S. K. Samanthapudi, Khanh Chau, Minh T. H. Nguyen, Jake Wen, Selina L. Hernandez Gonzalez, Shaefali P. Rodgers, Elizabeth A. Olmsted-Davis, Dale J. Hamilton, Cielito Reyes-Gibby, Sai-Ching J. Yeung, John P. Cooke, Joerg Herrmann, Eduardo N. Chini, Xiaolei Xu, Syed Wamique Yusuf, Momoko Yoshimoto, Philip L. Lorenzi, Brain Hobbs, Sunil Krishnan, Efstratios Koutroumpakis, Nicolas L. Palaskas, Guangyu Wang, Anita Deswal, Steven H. Lin, Jun-ichi Abe, Nhat-Tu Le
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 10 (2023)
Cardiovascular disease (CVD) is a leading cause of morbidity and mortality, especially among the aging population. The “response-to-injury” model proposed by Dr. Russell Ross in 1999 emphasizes inflammation as a critical factor in atherosclerosis
Externí odkaz:
https://doaj.org/article/f88dfe27f863446b91fe021a59c753ff
Autor:
Karla C. Maita, John P. Garcia, Francisco R. Avila, Ricardo A. Torres-Guzman, Olivia Ho, Claudia C.S. Chini, Eduardo N. Chini, Antonio J. Forte
Publikováno v:
Journal of Surgical Research. 288:329-340
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51d191d87044e9a8b8be70d42013216a
https://doi.org/10.1016/j.jss.2023.03.017
https://doi.org/10.1016/j.jss.2023.03.017
Akademický článek
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Autor:
Eduardo N. Chini, Daniel D. Billadeau, Jin-San Zhang, Mauro Sola-Penna, Carlos Escande, Veronica Nin, Anatilde M. Gonzalez Guerrico, Gourish Mondal, Jair M. Espindola-Netto, Claudia C.S. Chini
Purpose: Recent studies suggest that SIRT1-activating compounds (STAC) are a promising class of anticancer drugs, although their mechanism of action remains elusive. The main goal of this study is to determine the role of STACs as a potential therapy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3ff94669daf388b44790d9ec7501109
https://doi.org/10.1158/1078-0432.c.6523973.v1
https://doi.org/10.1158/1078-0432.c.6523973.v1
