Zobrazeno 1 - 10
of 206
pro vyhledávání: '"Eduardo Maffud, Cilli"'
Autor:
Biane Oliveira Philadelpho, Johnnie Elton Machado dos Santos, Emily Elaine Davis, Mariana Barros de Cerqueira e Silva, Eduardo Maffud Cilli, Ederlan de Souza Ferreira, Elvira González de Mejia
Publikováno v:
Journal of Functional Foods, Vol 122, Iss , Pp 106498- (2024)
The anticancer effect of digested β-vignin and pure peptides from cowpea beans was investigated in cultivated human colon cancer cells. The effect of AQQSY on the cell cycle was similar to that of palbociclib, suggesting that AQQSY may function as a
Externí odkaz:
https://doaj.org/article/f74c3583a66143f0b9d2ae8af5908a9c
Autor:
Gabriela Marinho Righetto, Norival Alves Santos-Filho, Letícia Oliveira Catarin Nunes, Camille André, Julia Medeiros Souza, Adriano Defini Andricopulo, Paulo José Martins Bispo, Eduardo Maffud Cilli, Ilana Lopes Baratella da Cunha Camargo
Publikováno v:
ACS Omega, Vol 9, Iss 22, Pp 23662-23674 (2024)
Externí odkaz:
https://doaj.org/article/a02e805ec1b54311a5ad713da11a3e78
Autor:
Biane Oliveira Philadelpho, Victória Guimarães Santiago, Johnnie Elton Machado dos Santos, Mariana Barros de Cerqueira e Silva, Rone Aparecido De Grandis, Eduardo Maffud Cilli, Fernando Rogério Pavan, Marcelo Santos Castilho, Alessio Scarafoni, Carolina Oliveira de Souza, Ederlan de Souza Ferreira
Publikováno v:
Foods, Vol 13, Iss 21, p 3508 (2024)
B-cell lymphoma 2 protein (Bcl-2) is an important regulator of cell apoptosis. Inhibitors that mirror the structural domain 3 (BH3) of Bcl-2 can activate apoptosis in cancer cells, making them a promising target for anticancer treatment. Hence, the p
Externí odkaz:
https://doaj.org/article/750d24836409490bb1057ef5e80a3af1
Autor:
Natalia C. S. Costa, Luana Ribeiro dos Anjos, João Victor Marcelino de Souza, Maria Carolina Oliveira de Arruda Brasil, Vitor Partite Moreira, Marcia A. S. Graminha, Gert Lubec, Eduardo Rene P. Gonzalez, Eduardo Maffud Cilli
Publikováno v:
ACS Omega, Vol 8, Iss 37, Pp 34008-34016 (2023)
Externí odkaz:
https://doaj.org/article/10e723e4584a4c7bbc515c2a2f60f4c5
Autor:
Ruben Siedlarczyk Nogueira, Bruno Ramos Salu, Vinícius Goulart Nardelli, Camila Ramalho Bonturi, Marina Rodrigues Pereira, Francisco Humberto de Abreu Maffei, Eduardo Maffud Cilli, Maria Luiza Vilela Oliva
Publikováno v:
Thrombosis Journal, Vol 21, Iss 1, Pp 1-10 (2023)
Highlights • Venom-analog peptide, (p-BthTX-I)2K, inhibits SARS-CoV-2 infection and papain-like protease. • Bothropstoxin-I-derived peptide analog shows antithrombotic action. • (p-BthTX-I)2K prolonged aPTT and PT by blocking kallikrein and fac
Externí odkaz:
https://doaj.org/article/e1bf81332ae6414280dcf3bf75028055
Autor:
Luana Mendonça Dias, Eduardo Maffud Cilli, Karine Sousa Medeiros, Maria Carolina Oliveira de Arruda Brasil, Lina Maria Marin, Walter L. Siqueira, Ana Claudia Pavarina
Publikováno v:
Microorganisms, Vol 12, Iss 1, p 99 (2024)
The aim of the study was to investigate the effect of antimicrobial peptides (AMPs) Hylin−a1, KR−12-a5, and Temporin-SHa in Candida albicans as well as the biocompatibility of keratinocytes spontaneously immortalized (NOK-si) and human gingival f
Externí odkaz:
https://doaj.org/article/53dba42b26ac4a998ed254850e6de038
Autor:
Gabriela Miranda Ayusso, Paulo Ricardo da Silva Sanches, Tamara Carvalho, Igor Andrade Santos, Daniel Oliveira Silva Martins, Maria Letícia Duarte Lima, Pâmela Jóyce Previdelli da Conceição, Cíntia Bittar, Andres Merits, Eduardo Maffud Cilli, Ana Carolina Gomes Jardim, Paula Rahal, Marilia Freitas Calmon
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1389 (2023)
Chikungunya virus (CHIKV) belongs to the Alphavirus genus and is responsible for significant outbreaks worldwide. Currently, there is no approved antiviral therapy against CHIKV. Bioactive peptides have great potential for new drug development. Here,
Externí odkaz:
https://doaj.org/article/9283c269cb444aa689c4f6b9e9027515
Autor:
Danilo da Silva Olivier, Graziely Ferreira Cespedes, Wallance Moreira Pazin, Eduardo Maffud Cilli, Amando Siuiti Ito
Publikováno v:
Eclética Química, Vol 46, Iss 1SI, Pp 30-40 (2021)
Dengue fever is a widespread infectious disease caused by Dengue viruses and responsible for millions of cases per year. One of the key steps during the infection is the fusion between the cell membrane and the lipidic bilayer of the virus, done by t
Externí odkaz:
https://doaj.org/article/10f19c7eca6748daa660fbc053fcc39b
Autor:
Paulo Ricardo da Silva Sanches, Ricardo Sanchez Velazquez, Mariana Nogueira Batista, Bruno Moreira Carneiro, Cintia Bittar, Giuditta De Lorenzo, Paula Rahal, Arvind H. Patel, Eduardo Maffud Cilli
Publikováno v:
Molecules, Vol 28, Iss 13, p 4884 (2023)
Re-emerging arboviruses represent a serious health problem due to their rapid vector-mediated spread, mainly in urban tropical areas. The 2013–2015 Zika virus (ZIKV) outbreak in South and Central America has been associated with cases of microcepha
Externí odkaz:
https://doaj.org/article/0f52ee7c6fd44cc59775a9ba297c6e48
Autor:
Gabriela Miranda Ayusso, Maria Letícia Duarte Lima, Paulo Ricardo da Silva Sanches, Igor Andrade Santos, Daniel Oliveira Silva Martins, Pâmela Jóyce Previdelli da Conceição, Tamara Carvalho, Vivaldo Gomes da Costa, Cíntia Bittar, Andres Merits, Norival Alves Santos-Filho, Eduardo Maffud Cilli, Ana Carolina Gomes Jardim, Marilia de Freitas Calmon, Paula Rahal
Publikováno v:
Viruses, Vol 15, Iss 5, p 1168 (2023)
Chikungunya virus (CHIKV) and Zika virus (ZIKV) are important disease-causing agents worldwide. Currently, there are no antiviral drugs or vaccines approved to treat these viruses. However, peptides have shown great potential for new drug development
Externí odkaz:
https://doaj.org/article/4339d1c05a874e65860d7a0b6b16447e