Mitochondria to plasma membrane redox signaling is essential for fatty acid β-oxidation-driven insulin secretion

Autor: Martin Jabůrek, Eduardo Klöppel, Pavla Průchová, Oleksandra Mozheitova, Jan Tauber, Hana Engstová, Petr Ježek

Publikováno v: Redox Biology, Vol 75, Iss , Pp 103283- (2024)

We asked whether acute redox signaling from mitochondria exists concomitantly to fatty acid- (FA-) stimulated insulin secretion (FASIS) at low glucose by pancreatic β-cells. We show that FA β-oxidation produces superoxide/H2O2, providing: i) mitoch

Externí odkaz: https://doaj.org/article/2c62519b300e44dfa58a44a1a60d3131

Comparison of streptozotocin-induced diabetes at different moments of the life of female rats for translational studies

Autor: Barshana Karki, Verônyca Gonçalves Paula, Carolina Miranda, Yuri Karen Sinzato, Gustavo Tadeu Volpato, Ana Paula da Silva de Campos, Débora Cristina Damasceno, Vaclav Hampl, Larissa F Alves, Lívia Ls Nascimento, Eduardo Kloppel

Publikováno v: Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP

Made available in DSpace on 2021-06-25T10:56:44Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-01-01 Animal models are widely used for studying diabetes in translational research. However, methods for induction of diabetes are conflicting wit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2e22261d259ee6ce3d3c04520eb96e11
https://doi.org/10.1177/00236772211001895

Repercussions of low fructose-drinking water in male rats

Autor: Yuri Karen Sinzato, Tatiele Estefâni Schönholzer, Débora Cristina Damasceno, Kleber Eduardo de Campos, Carolina Miranda, Eduardo Kloppel, Gustavo Tadeu Volpato

Publikováno v: Anais da Academia Brasileira de Ciências, Vol 91, Iss 1 (2019)
Scopus
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Anais da Academia Brasileira de Ciências v.91 n.1 2019
Anais da Academia Brasileira de Ciências
Academia Brasileira de Ciências (ABC)
instacron:ABC
Anais da Academia Brasileira de Ciências, Volume: 91, Issue: 1, Article number: e20170705, Published: 14 FEB 2019

Made available in DSpace on 2019-10-06T16:18:07Z (GMT). No. of bitstreams: 0 Previous issue date: 2019-01-01. Added 1 bitstream(s) on 2021-07-15T14:35:45Z : No. of bitstreams: 1 S0001-37652019000100702.pdf: 7025300 bytes, checksum: 9f180013f38351c25b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4011979641f15b1d48fc4579de7fc9ec
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0001-37652019000100702&lng=en&tlng=en

Effect of maternal obesity on insulin action in male adult offspring rats

Autor: Eduardo Kloppel, Kleber Eduardo de Campos, Gustavo Tadeu Volpato, Yuri Karen Sinzato, Débora Cristina Damasceno

Publikováno v: Diabetology & Metabolic Syndrome

Materials and methods twelve newborn female Wistar rats were used, and half of them submitted to saline solution administration (control) and the other half were administrated monosodium glutamate solution, 4.0 mg/Kg body weight (obese) in neonatal p

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a05638956910ef7c7ca19151756832
https://doi.org/10.1186/1758-5996-7-s1-a127

Study of Duguetia furfuracea aqueous extract treatment in metabolic profile and renal fuction biomarkers of obese Wistar dams

Autor: Dener Lucas Araújo dos Santos, Aline Zanatta Schavinski, Kleber Eduardo de Campos, Dionys de Souza Almeida, Eduardo Kloppel, Carolina Miranda, Amanda Lima Deluque

Publikováno v: Diabetology & Metabolic Syndrome

Background Obesity is a pathophysiology condition that influences the metabolic pathways, and the association with pregnancy can worsen the lipidic and glycemic profiles. Moreover, Duguetia furfuracea has been used for obesity and also kidney disease

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e91abd9d2f3bf5a0bde6a8f476755882
http://europepmc.org/articles/PMC4653521