Transcriptomic rationale for synthetic lethality-targeting ERCC1 and CDKN1A in chronic myelomonocytic leukaemia

Autor: Lurdes Zamora, Ginés Luengo-Gil, María Díez-Campelo, Marıa Del Canizo, Kiran Batta, Francisca Ferrer-Marín, Francisco José Ortuño, Eva Caparrós, Maria Luz Amigo, Tzu Hua Chen-Liang, Francesc Solé, Laura Palomo, Bartlomiej P Przychodzen, Eva Lumbreras, Daniel H. Wiseman, Andres Jerez, Jaroslaw P. Maciejewski, Fabio M. R. Amaral, Ana María Hurtado, Eduardo J Salido Fierrez, Vicente Vicente

Publikováno v: Br J Haematol
British Journal of Haematology
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
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Despite the absence of mutations in the DNA repair machinery in myeloid malignancies, the advent of high-throughput sequencing and discovery of splicing and epigenetics defects in chronic myelomonocytic leukaemia (CMML) prompted us to revisit a patho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09d0c181f3a0403ea26a81860bcf1a06
https://pubmed.ncbi.nlm.nih.gov/29797327