Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Eduardo J Folco"'
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152474 (2016)
AIMS:Mice deficient in IL-1 receptor 1 (hence unresponsive to both IL-1 isoforms α and β) have impaired expansive arterial remodeling due to diminished expression of matrix-degrading enzymes, especially MMP-3. Emergence of IL-1 as a target in cardi
Externí odkaz:
https://doaj.org/article/e2d7863b27094ec39d06e593ec76e15c
Autor:
Julio F. Marchini, Andre Manica, Paulo Crestani, Jochen Dutzmann, Eduardo J. Folco, Heinz Weber, Peter Libby, Kevin Croce
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 9, Iss 15 (2020)
Background Activated vascular cells produce submicron prothrombotic and proinflammatory microparticle vesicles. Atherosclerotic plaques contain high levels of microparticles. Plasma microparticle levels increase during acute coronary syndromes and th
Externí odkaz:
https://doaj.org/article/4a590055fb914cb69c7c7430383fe038
Autor:
Grasiele Sausen, Frederik Kloss, Mi Kyung Yu, Gha Young Lee, Roberto Molinaro, Eduardo J. Folco, Jinjun Shi, Omid C. Farokhzad, Peter Libby, Yevgenia Tesmenitsky, Kevin Croce, Claudia Corbo, Galina K. Sukhova, Colette A. Bichsel, Eugenia Shvartz, Yuan Liu
Publikováno v:
Cardiovasc Res
Aims Recent evidence suggests that ‘vulnerable plaques’, which have received intense attention as underlying mechanism of acute coronary syndromes over the decades, actually rarely rupture and cause clinical events. Superficial plaque erosion has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c64b91fe1dfac79a82f4dbbe34fc73df
http://hdl.handle.net/10281/347768
http://hdl.handle.net/10281/347768
Autor:
Galina K. Sukhova, Benjamin L. Ebert, Roberto Molinaro, Eduardo J. Folco, Rob S. Sellar, Grasiele Sausen, Peter Libby, Amelie Vromman
Publikováno v:
Circulation. 142
Introduction: In the current era of intense LDL lowering, superficial erosion may be on the rise as a cause of ACS (25-30%). Experimental data on human atheromata support a role for neutrophils and the formation of neutrophil extracellular traps (NET
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::463b1e37705b9274f466fe49f7d987d2
https://doi.org/10.1161/circ.142.suppl_3.15575
https://doi.org/10.1161/circ.142.suppl_3.15575
Autor:
Andre Manica, Jochen Dutzmann, Eduardo J. Folco, Paulo Crestani, Heinz Weber, Julio Flávio Meirelles Marchini, Kevin Croce, Peter Libby
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Activated vascular cells produce submicron prothrombotic and proinflammatory microparticle vesicles. Atherosclerotic plaques contain high levels of microparticles. Plasma microparticle levels increase during acute coronary syndromes and th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19ff9cd0ca298a5ea8fc19dfb58b149
https://doi.org/10.1161/jaha.120.015878
https://doi.org/10.1161/jaha.120.015878
Autor:
Peter Libby, Eduardo J. Folco, Grégory Franck, Breno Bernardes-Souza, Amelie Vromman, Oscar Persson, Momotaro Nakamura, Francis W. Luscinskas, Gail Newton, Thomas L. Mawson
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 38:1901-1912
Objective— Coronary artery thrombosis can occur in the absence of plaque rupture because of superficial erosion. Erosion-prone atheromata associate with more neutrophil extracellular traps (NETs) than lesions with stable or rupture-prone characteri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63653580b17f88802256a20b8d1b29f7
https://doi.org/10.1161/atvbaha.118.311150
https://doi.org/10.1161/atvbaha.118.311150
Publikováno v:
Current Opinion in Lipidology. 28:434-441
The present review explores the mechanisms of superficial intimal erosion, a common cause of thrombotic complications of atherosclerosis.Human coronary artery atheroma that give rise to thrombosis because of erosion differ diametrically from those as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01f10ee6ad8676e5c2df8ee34f62bb1
https://doi.org/10.1097/mol.0000000000000440
https://doi.org/10.1097/mol.0000000000000440
Autor:
Peter Libby, Gregory R. Wojtkiewicz, Matthias Nahrendorf, Eduardo J. Folco, Filip K. Swirski, Amelie Vromman, Eugenia Shvartz, Victoria Ruvkun, Gustavo Santos Masson, Galina K. Sukhova, Yevgenia Tesmenitsky, Hermann Gram
Publikováno v:
Eur Heart J
Aims Targeting interleukin-1 (IL-1) represents a novel therapeutic approach to atherosclerosis. CANTOS demonstrated the benefits of IL-1β neutralization in patients post-myocardial infarction with residual inflammatory risk. Yet, some mouse data hav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8da96d71e592b11bb073f2291bb0b09
https://pubmed.ncbi.nlm.nih.gov/30929007
https://pubmed.ncbi.nlm.nih.gov/30929007
Autor:
Eduardo J. Folco, Andrew H. Lichtman, Grégory Franck, Yevgenia Tesmenitsky, Roberto Molinaro, Thomas L. Mawson, Peter Libby, Eugenia Shvartz, Xin Liu, Victoria Ruvkun, Jean-Baptiste Michel, Denisa D. Wagner, Kevin Croce, Galina K. Sukhova, Daniel Engelbertsen, Antonino Nicoletti
Publikováno v:
Circulation research. 123(1)
Rationale: Neutrophils likely contribute to the thrombotic complications of human atheromata. In particular, neutrophil extracellular traps (NETs) could exacerbate local inflammation and amplify and propagate arterial intimal injury and thrombosis. P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73d4a53bebfe6c61e64f0e0cb19a140d
https://pubmed.ncbi.nlm.nih.gov/29929967
https://pubmed.ncbi.nlm.nih.gov/29929967
Publikováno v:
Journal of Biological Chemistry. 287:36896-36904
Abundant experimental and clinical data support a modulatory role for adiponectin in inflammation, dysmetabolism, and disease. Because the activation of cells involved in innate and adaptive immunity contributes to the pathogenesis of diseases such a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9dd37f1e79cdcdbc429bd51158d62a2
https://doi.org/10.1074/jbc.m112.409516
https://doi.org/10.1074/jbc.m112.409516