Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Eduardo Gonzalez-Couto"'
Autor:
Daniel Tabas-Madrid, Alberto D. Pascual-Montano, Marta Martínez, Juan Elvira, Javier Setoain, Eduardo Gonzalez-Couto, Annette Bakker, Carlos Oscar S. Sorzano, Mónica Franch
Publikováno v:
Nucleic Acids Research
Drug repositioning, using known drugs for treating conditions different from those the drug was originally designed to treat, is an important drug discovery tool that allows for a faster and cheaper development process by using drugs that are already
Autor:
Nicola P. Caradonna, Giulia Lazzeroni, David C. Rubinsztein, Fiona M. Menzies, Alessia Tarditi, Venkata P. Satagopam, Valentina Porcari, Angeleen Fleming, Reinhard Schneider, Freddy Heitz, Chiara Caramelli, Birte Sönnichsen, Maria Jimenez-Sanchez, Carla Scali, Sara Imarisio, Michael Hannus, Giuseppe Pollio, Wun Lam, Daniela Diamanti, Catherine K. Xu, Eduardo Gonzalez-Couto, Arianna Nencini, Gian Luca Sardone, Andrea Caricasole, Cahir J. O'Kane, Matteo Andreini, Luisa Massai, Guido Marconi, Teresa Ed Dami
Publikováno v:
Nature chemical biology
Nature chemical biology, 11(5), 347–354. (2015).
Nature chemical biology, 11(5), 347–354. (2015).
Huntington’s disease (HD) is a currently incurable neurodegenerative condition caused by an abnormally expanded polyglutamine tract in huntingtin (HTT). We identified novel modifiers of mutant HTT toxicity by performing a large-scale “druggable g
Autor:
Freddy, Heitz, Salvatore, La Rosa, Eduardo, Gonzalez-Couto, Giovanni, Gaviraghi, Georg C, Terstappen
Publikováno v:
IDrugs : the investigational drugs journal. 11(9)
Huntington's disease (HD) is a rare neurodegenerative disorder that progressively destroys the mental capacity and motor control of patients. This loss of motor control results in abnormal body movements (chorea) - the hallmark of HD. Given that no d
Autor:
Letizia Magnoni, Andreas Kremer, Freddy Heitz, Roberto Raggiaschi, Eduardo Gonzalez-Couto, Georg C. Terstappen, Stefano Gotta, Silvia Matteoni
Publikováno v:
BMC Systems Biology, Vol 1, Iss Suppl 1, p P45 (2007)
Autor:
Stéphanie Carraud, Anne Niknejad, Patricia Rodriguez-Tomé, Nicolas Budin, Irène Fasso, Matteo Villain, Sophie Lagache, Abderrahim Karmime, Nicolas Pinaud, Marianne Paolini, Hassan Mattou, Nicolas Christmann, Eve Mahe, Nicolas Barrillat, Nadia Allet, Sylvain Raimondi, Lydie Bougueleret, Thierry Baussant, Paolo Botti, Camille Schmidt, Frederic Ranno, Cedric Saudrais, Denis Canet, Gerald Rossellat, Anne Gleizes, Nicolas Dafflon, Frédéric Perret, Benoît Depresle, Catherine Jeandenans, Pierre-Olivier Regamey, Samia Reffas, Celia Boiteau, Keith Rose, Hubert François Gaertner, Pascal Frauchiger, Isabelle Cusin, Jacques Colinge, Eduardo Gonzalez-Couto, Marc Moniatte, Alexandre Masselot, Diego Chiappe, Thomas Kowall, Pierre-Antoine Rey, Catherine Zwahlen
Publikováno v:
Proteomics. 4(8)
We present an integrated proteomics platform designed for performing differential analyses. Since reproducible results are essential for comparative studies, we explain how we improved reproducibility at every step of our laboratory processes, e.g. b
Publikováno v:
Nucleic acids research. 29(1)
Although a vast amount of life sciences data is generated in the form of images, most scientists still store images on extremely diverse and often incompatible storage media, without any type of metadata structure, and thus with no standard facility
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 94(15)
Eukaryotic transcriptional activators may function by stimulating formation of RNA polymerase II preinitiation complexes at the core promoter of genes. In this case, their mode of action will intrinsically depend on how these complexes assemble on pr
Autor:
Martin Lundberg, Claes Andersson, Jan Stenvang, Joerg Schlingemann, Stine Buch Thorsen, Olle Nilsson, Mick Knowles, Eduardo Gonzalez Couto, Simon Fredriksson, Hans-Jorgen Nielsen, Björn Ekström, Birgitte Nielsen, Bonnie Tran, Erika Assarsson, Andrea Villablanca, Mats G. Gustafsson, Roberto Martin, Christian Fermér, Nils Brünner, Nick Gee, Ib Jarle Christensen
Publikováno v:
Molecular & Cellular Proteomics; Vol 10
A high throughput protein biomarker discovery tool has been developed based on multiplexed proximity ligation assays in a homogeneous format in the sense of no washing steps. The platform consists of four 24-plex panels profiling 74 putative biomarke
Autor:
Nadia Allet, Nicolas Barrillat, Thierry Baussant, Celia Boiteau, Paolo Botti, Lydie Bougueleret, Nicolas Budin, Denis Canet, Stéphanie Carraud, Diego Chiappe, Nicolas Christmann, Jacques Colinge, Isabelle Cusin, Nicolas Dafflon, Benoît Depresle, Irène Fasso, Pascal Frauchiger, Hubert Gaertner, Anne Gleizes, Eduardo Gonzalez-Couto
Publikováno v:
Proteomics; Aug2004, Vol. 4 Issue 8, p2333-2351, 19p