Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Eduardo Gomez-Castaneda"'
Autor:
Ilaria M. Michelozzi, Eduardo Gomez-Castaneda, Ruben V. C. Pohle, Ferran Cardoso Rodriguez, Jahangir Sufi, Pau Puigdevall Costa, Meera Subramaniyam, Efstratios Kirtsios, Ayad Eddaoudi, Si Wei Wu, Aleks Guvenel, Jonathan Fisher, Sara Ghorashian, Martin A. Pule, Christopher J. Tape, Sergi Castellano, Persis J. Amrolia, Alice Giustacchini
Publikováno v:
Blood advances.
We recently described a low-affinity second-generation CD19 chimeric antigen receptor (CAR) CAT that showed enhanced expansion, cytotoxicity, and antitumor efficacy compared with the high-affinity (FMC63-based) CAR used in tisagenlecleucel, in precli
Autor:
Brais Bea-Mascato, Eduardo Gómez-Castañeda, Yara E. Sánchez-Corrales, Sergi Castellano, Diana Valverde
Publikováno v:
Biology Direct, Vol 18, Iss 1, Pp 1-14 (2023)
Abstract Background Alström syndrome (ALMS) is a rare autosomal recessive disease that is associated with mutations in ALMS1 gene. The main clinical manifestations of ALMS are retinal dystrophy, obesity, type 2 diabetes mellitus, dilated cardiomyopa
Externí odkaz:
https://doaj.org/article/0f28d70848424b559a8a47c872a92d1d
Autor:
Ilaria M. Michelozzi, Eduardo Gomez Castaneda, Ruben V.C. Pohle, Ferran Cardoso Rodriguez, Jahangir Sufi, Pau Puigdevall Costa, Meera Subramaniyam, Efstratios Kirtsios, Ayad Eddaoudi, Si Wei Wu, Aleks Guvenel, Jonathan Fisher, Sara Ghorashian, Martin A. Pule, Christopher J. Tape, Sergi Castellano, Persis J. Amrolia, Alice Giustacchini
We recently described a low-affinity second-generation CD19 chimeric antigen receptor (CAR) CAT that showed enhanced expansion, cytotoxicity, and anti-tumour efficacy compared to the high-affinity (FMC63 based) CAR used in Tisagenlecleucel, in pre-cl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b79f0bbfa6bbb39f2b825d5e9d2ba484
https://doi.org/10.1101/2020.09.22.291831
https://doi.org/10.1101/2020.09.22.291831
Autor:
Ruben V.C. Pohle, Meera Subramaniyam, Sara Ghorashian, Jahangir Sufi, Martin Pule, Sergi Castellano, Ilaria M. Michelozzi, Persis Amrolia, Pau Puigdevall, Eduardo Gomez-Castaneda, Christopher J. Tape, Alice Giustacchini, Aleks Guvenel, Si Wei Wu, Ferran Cardoso Rodriguez
Publikováno v:
Blood. 136:52-53
We have recently described a low-affinity second-generation anti-CD19 Chimeric Antigen Receptor (CAR) (CAT), characterized by faster antigen dissociation rate which showed enhanced expansion, cytotoxicity and anti-tumour efficacy compared with the hi