Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Eduardo Gascon"'
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 17 (2023)
IntroductionAnimal models, especially rodents, have become instrumental to experimentally investigate the effects of an adverse post-natal environment on the developing brain. For this purpose, maternal separation (MS) paradigms have been widely used
Externí odkaz:
https://doaj.org/article/e257ef901e5d4e4e9654e8a190a7cec8
Autor:
Catherine Lepolard, Cynthia Rombaut, Florence Jaouen, Ana Borges, Elodie Caccomo-Garcia, Natalia Popa, Eduardo Gascon
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionAlthough intensively studied in the last decades, how microRNAs (miRNAs) are expressed across different cell types in the brain remains largely unknown.MaterialsTo address this issue, we sought to develop optimized fluorescence reporters
Externí odkaz:
https://doaj.org/article/c240636e4d254b0e9cc4cbab7abb2b86
Publikováno v:
EBioMedicine, Vol 82, Iss , Pp 104159- (2022)
Summary: Background: Psychiatric diseases such as depression and anxiety are multifactorial conditions, highly prevalent in western societies. Human studies have identified a number of high-risk genetic variants for these diseases. Among them, polymo
Externí odkaz:
https://doaj.org/article/83a395e6f1b6431fa8e170db818441a5
Autor:
Gwenaëlle Laverne, Jonathan Pesce, Ana Reynders, Etienne Combrisson, Eduardo Gascon, Christophe Melon, Lydia Kerkerian-Le Goff, Nicolas Maurice, Corinne Beurrier
Publikováno v:
Cell Reports, Vol 40, Iss 1, Pp 111034- (2022)
Summary: Striatal cholinergic interneurons (CINs) respond to salient or reward prediction-related stimuli after conditioning with brief pauses in their activity, implicating them in learning and action selection. This pause is lost in animal models o
Externí odkaz:
https://doaj.org/article/2b250a0aa1bb4743a8c116be1e2e2ca7
Autor:
Raoul Belzeaux, Victor Gorgievski, Laura M. Fiori, Juan Pablo Lopez, Julien Grenier, Rixing Lin, Corina Nagy, El Chérif Ibrahim, Eduardo Gascon, Philippe Courtet, Stéphane Richard-Devantoy, Marcelo Berlim, Eduardo Chachamovich, Jean-François Théroux, Sylvie Dumas, Bruno Giros, Susan Rotzinger, Claudio N. Soares, Jane A. Foster, Naguib Mechawar, Gregory G. Tall, Eleni T. Tzavara, Sidney H. Kennedy, Gustavo Turecki
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
It is not fully understood why some patients respond or do not respond to antidepressant treatment. Here the authors show that in the blood of individuals with depression, GPR56 expression increases in responders to antidepressant treatment, but not
Externí odkaz:
https://doaj.org/article/3469c4a94a4c4f539ae3e87d5f59f012
Publikováno v:
iScience, Vol 23, Iss 12, Pp 101790- (2020)
Summary: An extensive body of evidence supports the notion that exposure to an enriched/impoverished environment alters brain functions via epigenetic changes. However, how specific modifications of social environment modulate brain functions remains
Externí odkaz:
https://doaj.org/article/606fe11d7ec6442a82eb9fc70f6487b3
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 13 (2019)
An extensive literature details deterioration of multiple brain functions, especially memory and learning, during aging in humans and in rodents. In contrast, the decline of social functions is less well understood. It is presently not clear whether
Externí odkaz:
https://doaj.org/article/f6bdae8af813446e9a833b279eccbc55
Autor:
Yeliz Yuva-Aydemir, Xia-Lian Xu, Ozkan Aydemir, Eduardo Gascon, Serkan Sayin, Wenke Zhou, Yang Hong, Fen-Biao Gao
Publikováno v:
PLoS Genetics, Vol 11, Iss 5, p e1005264 (2015)
Intragenic microRNAs (miRNAs), located mostly in the introns of protein-coding genes, are often co-expressed with their host mRNAs. However, their functional interaction in development is largely unknown. Here we show that in Drosophila, miR-92a and
Externí odkaz:
https://doaj.org/article/e9ec18847de64f82b8e79d61b1a28402
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Akademický článek
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