Pharmacological differences in postoperative cutaneous sensitivity, pain at rest, and movement-induced pain in laparotomized mice

Autor: Miriam Santos-Caballero, Makeya A. Hasoun, Miguel Á. Huerta, M. Carmen Ruiz-Cantero, Miguel Á. Tejada, María Robles-Funes, Eduardo Fernández-Segura, Francisco J. Cañizares, Rafael González-Cano, Enrique J. Cobos

Publikováno v: Biomedicine & Pharmacotherapy, Vol 180, Iss , Pp 117459- (2024)

Postoperative pain management is challenging. We used mice with a transverse laparotomy to study tactile allodynia measured by the von Frey test, pain at rest measured by facial pain expressions detected by an artificial intelligence algorithm, and m

Externí odkaz: https://doaj.org/article/39151e38e8274dc997b7ab4595546507

SIGMA-1 RECEPTOR AGONISM EXACERBATES IMMUNE-DRIVEN NOCICEPTION: ROLE OF TRPV1+ NOCICEPTORS

Autor: Mari Carmen Ruiz-Cantero, Miguel Ángel Huerta, Miguel Á. Tejada, Eduardo Fernández-Segura, Francisco J. Cañizares, José Manuel Baeyens, Enrique J. Cobos

Publikováno v: IBRO Neuroscience Reports, Vol 15, Iss , Pp S712- (2023)

Externí odkaz: https://doaj.org/article/d661fbf6a6a2431ebbd48220a29033e4

Paclitaxel antitumor effect improvement in lung cancer and prevention of the painful neuropathy using large pegylated cationic liposomes

Autor: Julia Jiménez-López, Inmaculada Bravo-Caparrós, Laura Cabeza, Francisco R. Nieto, Raúl Ortiz, Gloria Perazzoli, Eduardo Fernández-Segura, Francisco J. Cañizares, José M. Baeyens, Consolación Melguizo, José Prados

Publikováno v: Biomedicine & Pharmacotherapy, Vol 133, Iss , Pp 111059- (2021)

Paclitaxel (PTX), a drug widely used in lung cancer, has serious limitations including the development of peripheral neurotoxicity, which may lead to treatment discontinuation and therapy failure. The transport of PTX in large cationic liposomes coul

Externí odkaz: https://doaj.org/article/236368c1584d4edca01b4d1234d16bd1

Heterozygous Arrhythmogenic Cardiomyopathy-desmoplakin Mutation Carriers Exhibit a Subclinical Cutaneous Phenotype with Cell Membrane Disruption and Lack of Intercellular Adhesion

Autor: Eduardo Fernández-Segura, Juan Jiménez-Jáimez, Angel Fernandez-Flores, Trinidad Montero-Vilchez, Francisco Javier Cañizares-García, Jesús Tercedor-Sánchez, Salvador Arias-Santiago, Eva Cabrera-Borrego, Francisco Bermúdez-Jiménez, María Molina-Jiménez, Rosa Macías-Ruiz, Luis Tercedor-Sánchez, Manuel Sánchez-Díaz

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname
Journal of Clinical Medicine
Volume 10
Issue 19
Journal of Clinical Medicine, Vol 10, Iss 4608, p 4608 (2021)

Genetic variants that result in truncation in desmoplakin (DSP) are a known cause of arrhythmogenic cardiomyopathy (AC). In homozygous carriers, the combined involvement of skin and heart muscle is well defined, however, this is not the case in heter

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76251629de84eaa90a9a6bf17bb1516f
http://hdl.handle.net/10481/70916

Paclitaxel antitumor effect improvement in lung cancer and prevention of the painful neuropathy using large pegylated cationic liposomes

Autor: Jose Prados, Inmaculada Bravo-Caparrós, José M. Baeyens, Consolación Melguizo, Francisco R. Nieto, F.J. Cañizares, Julia Jiménez-López, Eduardo Fernández-Segura, Gloria Perazzoli, Raúl Ortiz, Laura Cabeza

Publikováno v: Digibug. Repositorio Institucional de la Universidad de Granada
instname
Biomedicine & Pharmacotherapy, Vol 133, Iss, Pp 111059-(2021)
Digibug: Repositorio Institucional de la Universidad de Granada
Universidad de Granada (UGR)

Paclitaxel (PTX), a drug widely used in lung cancer, has serious limitations including the development of peripheral neurotoxicity, which may lead to treatment discontinuation and therapy failure. The transport of PTX in large cationic liposomes coul

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d97385e6f36875b969f4ec9d8edf3f
https://doi.org/10.1016/j.biopha.2020.111059