Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Eduardo F. Soto"'
Publikováno v:
ASN Neuro, Vol 2 (2010)
We have previously demonstrated that aTf (apotransferrin) accelerates maturation of OLs (oligodendrocytes) in vitro as well as in vivo. The purpose of this study is to determine whether aTf plays a functional role in a model of H/I (hypoxia/ischaemia
Externí odkaz:
https://doaj.org/article/3e0819856ef14c289b83b3294bb74c03
Publikováno v:
Experimental Neurology. 217:282-296
We have previously demonstrated that addition of low concentrations of lactacystin (a specific inhibitor of the proteasome) to oligodendroglial cell cultures containing a high percentage of precursor cells induces their exit from the cell cycle and t
Publikováno v:
Journal of Neuroscience Research. 86:2663-2673
We have used a model of iron deficiency in the rat to analyze the effects of a disruption in iron availability on oligodendroglial cell (OLGc) maturation and myelinogenesis and to explore the possible beneficial influence of an intracranial injection
Publikováno v:
Journal of Neurochemistry. 81:60-63
Recent findings have led to a better understanding of the roles of the ubiquitin (Ub) proteasome system in the progression of different human degenerative diseases. The neuropathological hallmarks of Alzheimer's disease (AD) are the neurofibrillary t
Autor:
A.L. Bertone Uña, Laura A. Pasquini, Violeta Millet, Juana M. Pasquini, C.A. Calatayud, Eduardo F. Soto
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
In order to further characterize the still unknown mechanism of cuprizone-induced demyelination, we investigated its effect on rat primary oligodendroglial cell cultures. Cell viability was not significantly affected by this treatment. However, when
Publikováno v:
Journal of Neuroscience Research. 82:822-830
Apotransferrin (aTf), has been shown to accelerate the differentiation of oligodendroglial cells (OLGcs) in primary cultures and to increase the expression of different components of the myelin cytoskeleton (CSK). We examined the incorporation and di
Publikováno v:
Developmental Neuroscience. 27:397-407
The selective degradation of abnormal or short half-life proteins in eukaryotic cells proceeds through the ubiquitin-mediated proteolytic system (UbPS). The signals that tag the proteins for their ubiquitination are well known. In the present study,
Autor:
Juana M. Pasquini, Eduardo F. Soto, Corina I. García, Anthony T. Campagnoni, Pablo M. Paez, Carlos Davio
Publikováno v:
Glia. 46:207-217
We have previously shown that addition of apotransferrin (aTf) accelerates maturation of oligodendroglial cells (OLGcs) in primary cultures. In this work, we examined the effect of aTf on two conditionally immortalized cell lines: N19 and N20.1. Thes
Publikováno v:
The Journal of Neuroscience. 23:4635-4644
We have used lactacystin, a specific inhibitor of the 26S proteasome, in oligodendroglial cell (OLGc) primary cultures to explore the possible participation of the proteasome–ubiquitin-dependent pathway in the decision of the OLGcs to arrest their
Publikováno v:
Glia. 42:406-416
In the central nervous system (CNS), apotransferrin (aTf) is produced by oligodendroglial cells (OLGcs), and aTf is essential for cell survival. We previously demonstrated that a single intracranial injection of aTf in 3-day-old rats accelerates diff