Modulation of the Pharmacological Activities of Secretory Phospholipase A2 from Crotalus durissus cascavella Induced by Naringin

Autor: Marcos H. Toyama, Ricardo Aparicio, Veronica C. G. Soares, Fábio H. R. Fagundes, Eduardo B. S. Diz-Filho, Simone C. B. Oliveira, Marcelo L. Santos, Camila A. Cotrim, Daniela O. Toyama

Publikováno v: Molecules, Vol 16, Iss 1, Pp 738-761 (2011)

In this work we have characterized the action of the naringin, a flavonoid found in grapefruit and known for its various pharmacological effects, which include antioxidant blood lipid lowering and anticancer activity, on the structure and biochemical

Externí odkaz: https://doaj.org/article/3f6d00f957cf4f2da8bb8415552bb5d9

Inhibition of Neurotoxic Secretory Phospholipases A2Enzymatic, Edematogenic, and Myotoxic Activities by Harpalycin 2, an Isoflavone Isolated fromHarpalyce brasilianaBenth

Autor: Edilberto R. Silveira, Rafael Matos Ximenes, Marcelo Zaldini Hernandes, Marcelo M. Rabello, Daniela de Oliveira Toyama, Fábio H. R. Fagundes, Eduardo B. S. Diz-Filho, Marcos H. Toyama, Henrique Hessel Gaeta, Veronica C. G. Soares, Renata Mendonça Araújo, Simone Cristina Buzzo, Helena Serra Azul Monteiro

Publikováno v: Evidence-Based Complementary and Alternative Medicine, Vol 2012 (2012)
Web of Science
Repositório Institucional da UNESP
Universidade Estadual Paulista (UNESP)
instacron:UNESP
Evidence-based Complementary and Alternative Medicine : eCAM

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Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f6c578c0cbefddfeb6ae5860aff53ef
https://doi.org/10.1155/2012/987517

Antiophidic solanidane steroidal alkaloids from Solanum campaniforme

Autor: Edilberto R. Silveira, Roberta Jeane Bezerra Jorge, Eduardo B. S. Diz-Filho, Janaina Serra Azul Monteiro Evangelista, Marcos H. Toyama, Helena Serra Azul Monteiro, Otília Deusdênia L. Pessoa, Maria Conceição M. Torres, Rafael Matos Ximenes, Raimundo Braz-Filho, Francisco das Chagas L. Pinto

Publikováno v: Journal of natural products. 74(10)

Three new solanidane alkaloids bearing a 22,23-epoxy ring (1-3) and four known compounds were isolated from leaves of Solanum campaniforme. The structures were determined using spectroscopic techniques, including 1D and 2D NMR, and HRESIMS experiment

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::462daacd48caca86ae18927e8a493dc0
https://pubmed.ncbi.nlm.nih.gov/21962208

Renal and cardiovascular effects of Bothrops marajoensis venom and phospholipase A2

Autor: Inez Liberato Evangelista, Nilberto R.F. Nascimento, Alice Maria Costa Martins, Alexandre Havt, Daniela de Oliveira Toyama, Helena Serra Azul Monteiro, Eduardo B. S. Diz-Filho, Manassés C. Fonteles, Terentia Batista Sá de Norões, Janaina Serra Azul Monteiro Evangelista, Marcos H. Toyama

Publikováno v: Toxicon : official journal of the International Society on Toxinology. 55(6)

Bothrops marajoensis is found in the savannah of Marajo Island in the State of Para and regions of Amapa State, Brazil. The aim of the work was to study the renal and cardiovascular effects of the B. marajoensis venom and phospholipase A(2) (PLA(2)).

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e5bead58c4e3d3e783550f9adfc98e8
https://pubmed.ncbi.nlm.nih.gov/20036276