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pro vyhledávání: '"Eduardo Augusto Vasconcelos de Freitas Ramalho"'
Autor:
Eduardo Augusto Vasconcelos de Freitas Ramalho, Hernando de Barros Siqueira Neto, Marina Galdino da Rocha Pitta, Ivan da Rocha Pitta
Publikováno v:
Clinical Cancer Drugs. 7:95-106
In the last four decades, the emphasis was laid on the research of small organic molecules with potential anti-cancer activity. Linezolid was the first oxazolidinone derivative approved by FDA for MRSA treatment. Despite its major role in antimicrobi
Autor:
Eduardo Augusto Vasconcelos de Freitas Ramalho, Douglas Carvalho Francisco Viana, Valécia de Cassia Mendonça da Costa, Maira Pitta, Moacyr Jesus Barreto de Melo Rêgo, Ivan da Rocha Pitta, Marina Galdino da Rocha Pitta
Publikováno v:
Medicinal chemistry (Shariqah (United Arab Emirates)). 18(9)
Background: Oxazolidinones display several biological effects, including anticancer activity. The purpose of this present work was to investigate a series of novel oxazolidinone derivatives with potential antineoplastic activity. Their mechanisms of