Zobrazeno 1 - 10 of 155 pro vyhledávání: '"Eduardo Arilla"'
1
Akademický článek
Reduction in Hippocampal Amyloid-β Peptide (Aβ) Content during Glycine-Proline-Glutamate (Gly-Pro-Glu) Co-Administration Is Associated with Changes in Inflammation and Insulin-like Growth Factor (IGF)-I Signaling
Autor: Laura M. Frago, Emma Burgos-Ramos, María Rodríguez-Pérez, Sandra Canelles, Eduardo Arilla-Ferreiro, Jesús Argente, Manuela G. López, Vicente Barrios
Publikováno v: International Journal of Molecular Sciences, Vol 25, Iss 11, p 5716 (2024)
Alzheimer’s disease (AD) is characterized by the deposition in the brain of senile plaques composed of amyloid-β peptides (Aβs) that increase inflammation. An endogenous peptide derived from the insulin-like growth factor (IGF)-I, glycine-proline
Externí odkaz: https://doaj.org/article/220b19f63d97437aa64ee0b640c236c0
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2
Akademický článek
Changes in Lipid Metabolism Enzymes in Rat Epididymal Fat after Chronic Central Leptin Infusion Are Related to Alterations in Inflammation and Insulin Signaling
Autor: María E. Casado, Sandra Canelles, Eduardo Arilla-Ferreiro, Laura M. Frago, Vicente Barrios
Publikováno v: International Journal of Molecular Sciences, Vol 24, Iss 8, p 7065 (2023)
Leptin inhibits food intake and reduces the size of body fat depots, changing adipocyte sensitivity to insulin to restrain lipid accrual. This adipokine may modulate the production of cytokines that could diminish insulin sensitivity, particularly in
Externí odkaz: https://doaj.org/article/4487f33869b347fc8c105f11362d9223
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3
Akademický článek
Chronic Central Leptin Infusion Promotes an Anti-Inflammatory Cytokine Profile Related to the Activation of Insulin Signaling in the Gastrocnemius of Male Rats
Autor: Vicente Barrios, Santiago Guerra-Cantera, Álvaro Martín-Rivada, Sandra Canelles, Ana Campillo-Calatayud, Eduardo Arilla-Ferreiro, Laura M. Frago, Julie A. Chowen, Jesús Argente
Publikováno v: Biomedicines, Vol 10, Iss 7, p 1465 (2022)
Leptin is involved in the modulation of insulin signaling in peripheral tissues, being closely associated with changes in lipid metabolism. This adipokine modifies inflammatory pathways that can interact with insulin targets in peripheral organs; how
Externí odkaz: https://doaj.org/article/5f3806f5c94640359bef140533e32ab0
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4
Akademický článek
Actinomycin D Arrests Cell Cycle of Hepatocellular Carcinoma Cell Lines and Induces p53-Dependent Cell Death: A Study of the Molecular Mechanism Involved in the Protective Effect of IRS-4
Autor: Luis G. Guijarro, Patricia Sanmartin-Salinas, Eva Pérez-Cuevas, M. Val Toledo-Lobo, Jorge Monserrat, Sofia Zoullas, Miguel A. Sáez, Miguel Angel Álvarez-Mon, Julia Bujan, Fernando Noguerales-Fraguas, Eduardo Arilla-Ferreiro, Melchor Álvarez-Mon, Miguel A. Ortega
Publikováno v: Pharmaceuticals, Vol 14, Iss 9, p 845 (2021)
Actinomycin D (ActD) is an FDA-approved NCI oncology drug that specifically targets and downregulates stem cell transcription factors, which leads to a depletion of stem cells within the tumor bulk. Recently, our research group demonstrated the impor
Externí odkaz: https://doaj.org/article/18c02be1681b49e4a41af447bc4866e0
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5
Akademický článek
Leptin Modulates the Response of Brown Adipose Tissue to Negative Energy Balance: Implication of the GH/IGF-I Axis
Autor: Vicente Barrios, Laura M. Frago, Sandra Canelles, Santiago Guerra-Cantera, Eduardo Arilla-Ferreiro, Julie A. Chowen, Jesús Argente
Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 6, p 2827 (2021)
The growth hormone (GH)/insulin-like growth factor I (IGF-I) axis is involved in metabolic control. Malnutrition reduces IGF-I and modifies the thermogenic capacity of brown adipose tissue (BAT). Leptin has effects on the GH/IGF-I axis and the functi
Externí odkaz: https://doaj.org/article/5f0f8660ed7f453e8e3a0116715560e6
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6
Akademický článek
Adipose tissue promotes a serum cytokine profile related to lower insulin sensitivity after chronic central leptin infusion.
Autor: Emma Burgos-Ramos, Sandra Canelles, Arancha Perianes-Cachero, Eduardo Arilla-Ferreiro, Jesús Argente, Vicente Barrios
Publikováno v: PLoS ONE, Vol 7, Iss 10, p e46893 (2012)
Obesity is an inflammatory state characterized by an augment in circulating inflammatory factors. Leptin may modulate the synthesis of these factors by white adipose tissue decreasing insulin sensitivity. We have examined the effect of chronic centra
Externí odkaz: https://doaj.org/article/cc0beb8981fb4d859a3d807e4237a6b8
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7
Actinomycin D Arrests Cell Cycle of Hepatocellular Carcinoma Cell Lines and Induces p53-Dependent Cell Death: A Study of the Molecular Mechanism Involved in the Protective Effect of IRS-4
Autor: Patricia Sanmartín-Salinas, Miguel A Ortega, Melchor Alvarez-Mon, M Val Toledo-Lobo, Eva Pérez-Cuevas, Luis G. Guijarro, Miguel Angel Alvarez-Mon, Miguel A Saez, Fernando Noguerales-Fraguas, Julia Buján, Sofia Zoullas, Eduardo Arilla-Ferreiro, Jorge Monserrat
Publikováno v: Pharmaceuticals
Volume 14
Issue 9
Pharmaceuticals, Vol 14, Iss 845, p 845 (2021)
Actinomycin D (ActD) is an FDA-approved NCI oncology drug that specifically targets and downregulates stem cell transcription factors, which leads to a depletion of stem cells within the tumor bulk. Recently, our research group demonstrated the impor
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e63c7883f39da102f0e4682fdf5575a5
https://pubmed.ncbi.nlm.nih.gov/34577545
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9
6041. Finalista / Finalist
Autor: Eduardo Arilla, Blanca Hernandez, Francisco Muñoz
Publikováno v: Memoria de Proyectos. :18-21
Devoción ritual es la capilla la capilla de una universidad el ritual es inspirado la devoción es personal inspirado por un gran maestro, el afortunado joven, al pasar echa una mirada a la capilla, siente la devoción y realiza su ritual. él ha es
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::71af05521598bf411465972bdef055df
https://doi.org/10.15581/023.2.38174
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10
Leptin Modulates the Response of Brown Adipose Tissue to Negative Energy Balance: Implication of the GH/IGF-I Axis
Autor: Santiago Guerra-Cantera, Julie A. Chowen, Sandra Canelles, Jesús Argente, Laura M. Frago, Eduardo Arilla-Ferreiro, Vicente Barrios
Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 6
Biblos-e Archivo. Repositorio Institucional de la UAM
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International Journal of Molecular Sciences, Vol 22, Iss 2827, p 2827 (2021)
The growth hormone (GH)/insulin-like growth factor I (IGF-I) axis is involved in metabolic control. Malnutrition reduces IGF-I and modifies the thermogenic capacity of brown adipose tissue (BAT). Leptin has effects on the GH/IGF-I axis and the functi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1e1c941fc8bea618a2fa912b7d3fa65
http://europepmc.org/articles/PMC8001882
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