Výsledky vyhledávání - "Eduarda Guerreiro"

Cancer cell line-specific protein profiles in extracellular vesicles identified by proteomics

Autor: Hilde Kanli Galtung, Daniela Elena Costea, Reidun Øvstebø, Bernd Thiede, T.M. Søland, Eduarda Guerreiro

Publikováno v: e0238591
PLoS ONE, Vol 15, Iss 9, p e0238591 (2020)
PLOS ONE
15:e0238591
PLoS ONE

Extracellular vesicles (EVs), are important for intercellular communication in both physiological and pathological processes. To explore the potential of cancer derived EVs as disease biomarkers for diagnosis, monitoring, and treatment decision, it i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf1d1a9a6429b3d773d294339560f5d5
https://hdl.handle.net/11250/2739764

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Proteomic and histopathological characterisation of sicca subjects and primary Sjögren’s syndrome patients reveals promising tear, saliva and extracellular vesicle disease biomarkers

Autor: Hilde Kanli Galtung, Bernd Thiede, Xiangjun Chen, Øyvind Palm, Øygunn Aass Utheim, Tor Paaske Utheim, Eduarda Guerreiro, Reidun Øvstebø, Janicke Liaaen Jensen, Kathrine Skarstein, Lara A. Aqrawi

Publikováno v: Arthritis Research & Therapy
Arthritis Research & Therapy, Vol 21, Iss 1, Pp 1-14 (2019)

Background Mononuclear cell infiltration of exocrine glands, production of Ro/SSA and La/SSB autoantibodies, along with oral and ocular dryness, are characteristic features of primary Sjögren’s syndrome (pSS). Non-SS sicca subjects, an underexplor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c561d325a13bc480fc3b9a27fc3f97
https://doi.org/10.1186/s13075-019-1961-4

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Efficient extracellular vesicle isolation by combining cell media modifications, ultrafiltration, and size-exclusion chromatography

Autor: Reidun Øvstebø, Hans Christian Dalsbotten Aass, Daniela Elena Costea, Beate Vestad, Muhammad Saeed, Hilde Kanli Galtung, T.M. Søland, Lilly Alice Steffensen, Eduarda Guerreiro

Publikováno v: PLoS ONE
PLoS ONE, Vol 13, Iss 9, p e0204276 (2018)

Extracellular vesicles (EVs) are a heterogeneous population of biological particles released by cells. They represent an attractive source of potential biomarkers for early detection of diseases such as cancer. However, it is critical that sufficient

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f54bcce0dbebad150b586368cc5cc948
http://hdl.handle.net/10852/72215

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FBXL5 modulates HIF-1α transcriptional activity by degradation of CITED2

Autor: Ivette Pacheco-Leyva, Gisela Machado-Oliveira, Ana Catarina Matias, Joao M. Facucho-Oliveira, José Bragança, Eduarda Guerreiro

Publikováno v: Archives of Biochemistry and Biophysics. 576:61-72

CITED2 is a ubiquitously expressed nuclear protein exhibiting a high affinity for the cysteine-histidine-rich domain 1 (CH1) of the transcriptional co-activators CBP/p300. CITED2 is particularly efficient in the inhibition of the hypoxia-inducible fa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43feda9b6f623c77b4ab0c3d6ddd1e53
https://doi.org/10.1016/j.abb.2015.04.012

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Identification of potential saliva and tear biomarkers in primary Sjögren’s syndrome, utilising the extraction of extracellular vesicles and proteomics analysis

Autor: Øyvind Palm, Beate Vestad, Eduarda Guerreiro, Hilde Kanli Galtung, Janicke Liaaen Jensen, Shermin Rusthen, Tor Paaske Utheim, Reidun Øvstebø, Øygunn Aass Utheim, Bernd Thiede, Xiangjun Chen, Lara A. Aqrawi, Alix Young

Publikováno v: Arthritis Research & Therapy

Background There is a long-lasting need for non-invasive, more accurate diagnostic techniques when evaluating primary Sjögren’s syndrome (pSS) patients. Incorporation of additional diagnostics involving screening for disease-specific biomarkers in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7fb58b201955016e8daac1c103edd54
http://hdl.handle.net/10852/53653

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Triclosan interferes with the thyroid axis in the zebrafish (Danio rerio)

Autor: Deborah M. Power, Eduarda Guerreiro, Patrícia Pinto

Publikováno v: Toxicol. Res.. 2:60-69

This study focuses on the effects of triclosan (TCS), a ubiquitous antimicrobial agent and aquatic contaminant, on the thyroid of adult zebrafish. The morphology of the thyroid was modified after short term (21 days) dietary exposure of zebrafish to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1c85bf9f3705b854c857a6980a440198
https://doi.org/10.1039/c2tx20005h

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CITED2 Cooperates with ISL1 and Promotes Cardiac Differentiation of Mouse Embryonic Stem Cells

Autor: Annebel Marjolein van de Vrugt, Ivette Pacheco-Leyva, Daniel V. Oliveira, Rita Nascimento, João M.A. Santos, Ana Catarina Matias, Eduarda Guerreiro, Gisela Machado-Oliveira, Ibrahim J. Domian, Anna C. Michell, José Bragança, Guilherme Ferreira

Publikováno v: Stem Cell Reports
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP

Summary The transcriptional regulator CITED2 is essential for heart development. Here, we investigated the role of CITED2 in the specification of cardiac cell fate from mouse embryonic stem cells (ESC). The overexpression of CITED2 in undifferentiate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cec4738342eb7cc980a46c20cb45d75
https://pubmed.ncbi.nlm.nih.gov/27818139

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