Výsledky vyhledávání - "Eduarda Doneda"

The challenge of flavonoid/cyclodextrin complexation in a complex matrix of the quercetin, luteolin, and 3-O-methylquercetin

Autor: Vanessa Pittol, Kleyton Santos Veras, Eduarda Doneda, Ariane Dorneles Silva, Maria Gabriele Delagustin, Letícia Scherer Koester, Valquíria Linck Bassani

Publikováno v: Pharmaceutical Development and Technology. 27:625-634

The complexation of herbal constituents with cyclodextrin has been a useful tool to improve their aqueous solubility. However, the simultaneous complexation of these compounds still lacks detailed studies. The present study investigated the multicomp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7bf5d0f82d762677f12407186bf763
https://doi.org/10.1080/10837450.2022.2098326

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The challenge of flavonoid/cyclodextrin complexation in a complex matrix of the quercetin, luteolin, and 3

Autor: Vanessa, Pittol, Kleyton Santos, Veras, Eduarda, Doneda, Ariane Dorneles, Silva, Maria Gabriele, Delagustin, Letícia Scherer, Koester, Valquíria Linck, Bassani

Publikováno v: Pharmaceutical development and technology. 27(6)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::5ae6057528bbbf38d55b02ab5d931b14
https://pubmed.ncbi.nlm.nih.gov/35796030

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3-O-Methylquercetin from Achyrocline satureioides—cytotoxic activity against A375-derived human melanoma cell lines and its incorporation into cyclodextrins-hydrogels for topical administration

Autor: Valquiria Linck Bassani, Fabrício Figueiró, Irene L. Ibañez, Tainá Kreutz, Sara Elis Bianchi, Vanessa Pittol, Fábio Klamt, Hebe Duran, Eduarda Doneda, Candelaria Bracalente, Juliete Nathali Scholl

Publikováno v: Drug Delivery and Translational Research. 11:2151-2168

3-O-Methylquercetin (3OMQ), a natural 3-O-methylflavonoid, was isolated from Achyrocline satureioides and purified using the high-performance counter current chromatography (HPCCC) on a semi-preparative scale. High-purity 3OMQ (98%) was obtained with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::128e296b2717a7a9022bb9f95c93b5ad
https://doi.org/10.1007/s13346-020-00882-6

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Achyrocline satureioides compounds, achyrobichalcone and 3‐ O ‐methylquercetin, induce mitochondrial dysfunction and apoptosis in human breast cancer cell lines

Autor: Valquiria Linck Bassani, Camila Kehl Dias, V. Ashutosh Rao, Melissa A Pegues, Sara Elis Bianchi, Francesca Mascia, Vanessa Pittol, Eduarda Doneda, Fábio Klamt

Publikováno v: IUBMB Life. 72:2133-2145

Natural products are a valuable source of new molecules and are important for drug discovery. Many chemotherapeutics currently in clinical use were originated from natural sources and are effective cytotoxic agents. In this study, we investigated the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24cb9ee5645627ccd9504c97a33d7a9c
https://doi.org/10.1002/iub.2348

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Semi-preparative isolation and purification of phenolic compounds from Achyrocline satureioides (Lam) D.C. by high-performance counter-current chromatography

Autor: Sara Elis Bianchi, Eduarda Doneda, Kellen Cristhinia Borges de Souza, Valquiria Linck Bassani, Vanessa Pittol, Samuel Kaiser

Publikováno v: Phytochemical Analysis. 30:182-192

Introduction Phenolic compounds present in Achyrocline satureioides are known to have therapeutic benefits like antioxidant, anti-inflammatory, and antitumour properties. The main polyphenols present in the plant are quercetin (QCT), luteolin (LUT),

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25bdb687fbb9f2b342492528e30bebf3
https://doi.org/10.1002/pca.2803

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