Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Eduard V Bocharov"'
Autor:
Vladislav A Lushpa, Marina V Goncharuk, Irina A Talyzina, Alexander S Arseniev, Eduard V Bocharov, Konstantin S Mineev, Sergey A Goncharuk
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0304997 (2024)
Toll-like receptors (TLRs) are key players in the innate immune system. Despite the great efforts in TLR structural biology, today we know the spatial structures of only four human TLR intracellular TIR domains. All of them belong to one of five subf
Externí odkaz:
https://doaj.org/article/9761a2e62c224787ad9499a872968cd1
Facade-Based Bicelles as a New Tool for Production of Active Membrane Proteins in a Cell-Free System
Autor:
Marina V. Goncharuk, Ekaterina V. Vasileva, Egor A. Ananiev, Andrey Y. Gorokhovatsky, Eduard V. Bocharov, Konstantin S. Mineev, Sergey A. Goncharuk
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 19, p 14864 (2023)
Integral membrane proteins are important components of a cell. Their structural and functional studies require production of milligram amounts of proteins, which nowadays is not a routine process. Cell-free protein synthesis is a prospective approach
Externí odkaz:
https://doaj.org/article/3b4d61702c3c4572a769e4cf5e4a5e90
Autor:
Vladimir D. Krasnobaev, Yaroslav V. Bershatsky, Olga V. Bocharova, Eduard V. Bocharov, Oleg V. Batishchev
Publikováno v:
Membranes, Vol 13, Iss 8, p 706 (2023)
One of the hallmarks of Alzheimer’s disease (AD) is the accumulation of amyloid beta (Aβ) peptides in the brain. The processing of amyloid precursor protein (APP) into Aβ is dependent on the location of APP in the membrane, membrane lipid composi
Externí odkaz:
https://doaj.org/article/b25979ecf2ab4069820d3e25ad924d01
Autor:
Yaroslav V. Bershatsky, Andrey S. Kuznetsov, Aisha R. Idiatullina, Olga V. Bocharova, Sofya M. Dolotova, Alina A. Gavrilenkova, Oxana V. Serova, Igor E. Deyev, Tatiana V. Rakitina, Olga T. Zangieva, Konstantin V. Pavlov, Oleg V. Batishchev, Vladimir V. Britikov, Sergey A. Usanov, Alexander S. Arseniev, Roman G. Efremov, Eduard V. Bocharov
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 4, p 3906 (2023)
Human InsR, IGF1R, and IRR receptor tyrosine kinases (RTK) of the insulin receptor subfamily play an important role in signaling pathways for a wide range of physiological processes and are directly associated with many pathologies, including neurode
Externí odkaz:
https://doaj.org/article/ac92b97b54cb44dc932ee544f43d4684
Autor:
Dmitry E. Petrenko, David M. Karlinsky, Veronika D. Gordeeva, Georgij P. Arapidi, Elena V. Britikova, Vladimir V. Britikov, Alena Y. Nikolaeva, Konstantin M. Boyko, Vladimir I. Timofeev, Inna P. Kuranova, Anna G. Mikhailova, Eduard V. Bocharov, Tatiana V. Rakitina
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2286 (2023)
The crystal structure of bacterial oligopeptidase B from Serratia proteamaculans (SpOpB) in complex with a chloromethyl ketone inhibitor was determined at 2.2 Å resolution. SpOpB was crystallized in a closed (catalytically active) conformation. A si
Externí odkaz:
https://doaj.org/article/e0116bbbdec643a49a797109a7bc81f5
Autor:
Vladimir V. Britikov, Eduard V. Bocharov, Elena V. Britikova, Natalia I. Dergousova, Olga G. Kulikova, Anastasia Y. Solovieva, Nikolai S. Shipkov, Larisa A. Varfolomeeva, Tamara V. Tikhonova, Vladimir I. Timofeev, Eleonora V. Shtykova, Dmitry A. Altukhov, Sergey A. Usanov, Alexander S. Arseniev, Tatiana V. Rakitina, Vladimir O. Popov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9969 (2022)
The search of a putative physiological electron acceptor for thiocyanate dehydrogenase (TcDH) newly discovered in the thiocyanate-oxidizing bacteria Thioalkalivibrio paradoxus revealed an unusually large, single-heme cytochrome c (CytC552), which was
Externí odkaz:
https://doaj.org/article/92fc435c03cf4dc5b2e1937cdccc14d3
Autor:
Camille Albrecht, Andrey S. Kuznetsov, Aline Appert-Collin, Zineb Dhaideh, Maïté Callewaert, Yaroslav V. Bershatsky, Anatoly S. Urban, Eduard V. Bocharov, Dominique Bagnard, Stéphanie Baud, Sébastien Blaise, Béatrice Romier-Crouzet, Roman G. Efremov, Manuel Dauchez, Laurent Duca, Marc Gueroult, Pascal Maurice, Amar Bennasroune
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Sialidases, or neuraminidases, are involved in several human disorders such as neurodegenerative, infectious and cardiovascular diseases, and cancers. Accumulative data have shown that inhibition of neuraminidases, such as NEU1 sialidase, may be a pr
Externí odkaz:
https://doaj.org/article/07a99ce083d34a60866086896cbe236a
Autor:
Pavel Volynsky, Diana Maltseva, Valentin Tabakmakher, Eduard V. Bocharov, Maria Raygorodskaya, Galina Zakharova, Elena Britikova, Alexander Tonevitsky, Roman Efremov
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 295 (2022)
Structurally similar catalytic subunits A of ricin (RTA) and viscumin (MLA) exhibit cytotoxic activity through ribosome inactivation. Ricin is more cytotoxic than viscumin, although the molecular mechanisms behind this difference are still poorly und
Externí odkaz:
https://doaj.org/article/5ec8577d28e848ae8a8bb6caa58571e9
Autor:
Anatoly S. Urban, Konstantin V. Pavlov, Anna V. Kamynina, Ivan S. Okhrimenko, Alexander S. Arseniev, Eduard V. Bocharov
Publikováno v:
Molecules, Vol 26, Iss 10, p 2897 (2021)
Alzheimer’s disease is the most common type of neurodegenerative disease in the world. Genetic evidence strongly suggests that aberrant generation, aggregation, and/or clearance of neurotoxic amyloid-β peptides (Aβ) triggers the disease. Aβ accu
Externí odkaz:
https://doaj.org/article/467b0090289a49c7a051faa36381a146
Autor:
Yury A. Gaponov, Vladimir I. Timofeev, Yulia K. Agapova, Eduard V. Bocharov, Eleonora V. Shtykova, Tatiana V. Rakitina
Publikováno v:
Mendeleev Communications. 32:742-744