Zobrazeno 1 - 10
of 101
pro vyhledávání: '"Eduard V, Bocharov"'
Autor:
Vladislav A Lushpa, Marina V Goncharuk, Irina A Talyzina, Alexander S Arseniev, Eduard V Bocharov, Konstantin S Mineev, Sergey A Goncharuk
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0304997 (2024)
Toll-like receptors (TLRs) are key players in the innate immune system. Despite the great efforts in TLR structural biology, today we know the spatial structures of only four human TLR intracellular TIR domains. All of them belong to one of five subf
Externí odkaz:
https://doaj.org/article/9761a2e62c224787ad9499a872968cd1
Autor:
Vladimir D. Krasnobaev, Yaroslav V. Bershatsky, Olga V. Bocharova, Eduard V. Bocharov, Oleg V. Batishchev
Publikováno v:
Membranes, Vol 13, Iss 8, p 706 (2023)
One of the hallmarks of Alzheimer’s disease (AD) is the accumulation of amyloid beta (Aβ) peptides in the brain. The processing of amyloid precursor protein (APP) into Aβ is dependent on the location of APP in the membrane, membrane lipid composi
Externí odkaz:
https://doaj.org/article/b25979ecf2ab4069820d3e25ad924d01
Autor:
Camille Albrecht, Andrey S. Kuznetsov, Aline Appert-Collin, Zineb Dhaideh, Maïté Callewaert, Yaroslav V. Bershatsky, Anatoly S. Urban, Eduard V. Bocharov, Dominique Bagnard, Stéphanie Baud, Sébastien Blaise, Béatrice Romier-Crouzet, Roman G. Efremov, Manuel Dauchez, Laurent Duca, Marc Gueroult, Pascal Maurice, Amar Bennasroune
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Sialidases, or neuraminidases, are involved in several human disorders such as neurodegenerative, infectious and cardiovascular diseases, and cancers. Accumulative data have shown that inhibition of neuraminidases, such as NEU1 sialidase, may be a pr
Externí odkaz:
https://doaj.org/article/07a99ce083d34a60866086896cbe236a
Autor:
Pavel Volynsky, Diana Maltseva, Valentin Tabakmakher, Eduard V. Bocharov, Maria Raygorodskaya, Galina Zakharova, Elena Britikova, Alexander Tonevitsky, Roman Efremov
Publikováno v:
Biomolecules, Vol 12, Iss 2, p 295 (2022)
Structurally similar catalytic subunits A of ricin (RTA) and viscumin (MLA) exhibit cytotoxic activity through ribosome inactivation. Ricin is more cytotoxic than viscumin, although the molecular mechanisms behind this difference are still poorly und
Externí odkaz:
https://doaj.org/article/5ec8577d28e848ae8a8bb6caa58571e9
Autor:
Anatoly S. Urban, Konstantin V. Pavlov, Anna V. Kamynina, Ivan S. Okhrimenko, Alexander S. Arseniev, Eduard V. Bocharov
Publikováno v:
Molecules, Vol 26, Iss 10, p 2897 (2021)
Alzheimer’s disease is the most common type of neurodegenerative disease in the world. Genetic evidence strongly suggests that aberrant generation, aggregation, and/or clearance of neurotoxic amyloid-β peptides (Aβ) triggers the disease. Aβ accu
Externí odkaz:
https://doaj.org/article/467b0090289a49c7a051faa36381a146
Autor:
Yury A. Gaponov, Vladimir I. Timofeev, Yulia K. Agapova, Eduard V. Bocharov, Eleonora V. Shtykova, Tatiana V. Rakitina
Publikováno v:
Mendeleev Communications. 32:742-744
Autor:
Timur N. Bozin, Igor M. Berdyshev, Ksenia N. Chukhontseva, Maria A. Karaseva, Petr V. Konarev, Anna M. Varizhuk, Dmitry M. Lesovoy, Alexander S. Arseniev, Sergey V. Kostrov, Eduard V. Bocharov, Ilya V. Demidyuk
Publikováno v:
The journal of biological chemistry 299(4), 104585 (2023). doi:10.1016/j.jbc.2023.104585
J Biol Chem
J Biol Chem
The journal of biological chemistry 299(4), 104585 (2023). doi:10.1016/j.jbc.2023.104585
Emfourin (M4in) is a protein metalloprotease inhibitor recently discovered in the bacterium Serratia proteamaculans and the prototype of a new family of pro
Emfourin (M4in) is a protein metalloprotease inhibitor recently discovered in the bacterium Serratia proteamaculans and the prototype of a new family of pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0777c657514a5578e5ecc6b0f7e83643
Publikováno v:
Crystallography Reports. 66:737-750
Alzheimer’s disease is the most widespread form of neurodegenerative disease in the world. Its clinical manifestations are explained by selective degeneration of neurons in the portions of cerebral cortex responsible for cognitive perception and me
Autor:
Wolfgang Bermel, Eduard V. Bocharov, Vladislav Yu. Orekhov, Björn M. Burmann, Irena Matečko-Burmann, Panagiota S. Georgoulia, Dmitry M. Lesovoy, Tammo Diercks
Publikováno v:
Angewandte Chemie (International Ed. in English)
Dysregulation of post‐translational modifications (PTMs) like phosphorylation is often involved in disease. NMR may elucidate exact loci and time courses of PTMs at atomic resolution and near‐physiological conditions but requires signal assignmen
Autor:
Vasily V. Filatov, Eduard V. Bocharov, Ksenia N. Chukhontseva, Ilya V. Demidyuk, Viacheslav I. Kozlovskiy, Timur N. Bozin, Dmitry M. Lesovoy
Publikováno v:
Biomolecular NMR Assignments. 15:361-366
Emfourin (M4in) from Serratia proteamaculans is a new proteinaceous inhibitor of protealysin-like proteases (PLPs), a subgroup of the well-known and widely represented metallopeptidase M4 family. Although the biological role of PLPs is debatable, dat