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pro vyhledávání: '"Eduard Montana"'
Diminished Fraction of Blockable ATP-Sensitive K+ Channels in Islets Transplanted Into Diabetic Mice
Autor:
Franz Martín, Eduard Montana, Bernat Soria, Víctor Nacher, Etelvina Andreu, Juan Vicente Sánchez-Andrés
Publikováno v:
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
instname
Dipòsit Digital de la UB
Universidad de Barcelona
Digital.CSIC. Repositorio Institucional del CSIC
The reasons for the poor outcome of islet transplantation in diabetic patients are not well known; a better understanding of the pathophysiology of transplanted islets is needed. To study the mechanism coupling secretagogue stimuli with insulin relea
Publikováno v:
Europe PubMed Central
In streptozocin (SZ)-induced diabetic mice, 200 islets, but not 50 islets, consistently restore euglycemia within 1 week of transplantation. To determine the minimum number of islets sufficient to maintain euglycemia in a diabetic mouse, we first tra