Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Eduard E. Holdener"'
Autor:
Peter Dalquen, Rudolf Joss, Pierre Alberto, Serge Leyvraz, Hans-Jörg Senn, Franco Cavalli, Eduard E. Holdener, P. Siegenthaler, C. Ludwig, K. Bürki, Rolf A. Stahel, Ernst Schatzmann
Publikováno v:
Cancer. 65:2426-2434
From 1984 through 1986, 205 patients with non-small cell lung cancer were entered into a group-wide trial of the Swiss Group for Clinical Cancer Research (SAKK). This trial evaluated the combination of mitomycin (8 mg/m2 intravenously [IV] on day 1),
Publikováno v:
International Journal of Cancer. 50:868-870
Five partial responses were seen in 23 patients with metastatic renal-cell carcinoma (MRCC) receiving interferon-alpha 2a (IFN)+prednisone (P). Four of 24 subsequent patients responded to IFN+P (combined response rate 19%). The median response durati
Autor:
Wim W. ten Bokkel Huinink, Otto Klepp, Cristina Sessa, C. Ludwig, Eduard E. Holdener, Michel Clavel, Genevieve Decoster, Herbert M. Pinedo, Georgette Renard, P. Siegenthaler
Publikováno v:
European journal of cancer (Oxford, England : 1990). (3)
Anaxirone, a rationally synthesised triepoxide derivative, was given to 46 patients with metastatic colorectal cancer. Good risk patients received 800 mg/m(2) as a rapid intravenous injection every 4 weeks, whereas poor risk patients received 650 mg/
Autor:
Eduard E. Holdener, Werner Bollag
Publikováno v:
Current opinion in oncology. 5(6)
This review highlights recent advances in understanding the mode of action of retinoids at the level of molecular and cellular biology in relation to the new clinical results achieved with retinoids in various malignancies. All-trans-retinoic acid ha
Autor:
Eduard E. Holdener, Christian Ludwig, Georgette Renard, Genevieve Decoster, Herbert M. Pinedo, Wim W. ten Bokkel Huinink
Publikováno v:
Investigational New Drugs. 6:227-230
Menogaril, a new semisynthetic anthracycline antibiotic, was administered to 35 patients with advanced colorectal cancer. The drug was infused over 2 hr at a dose of 160 mg/sqm or 200 mg/sqm repeated every 4 weeks. Twenty-seven patients were evaluabl
Autor:
J. Renard, Heine H. Hansen, U. Bruntsch, Eduard E. Holdener, Herbert M. Pinedo, Hans Høst, Marcel Rozencweig, Franco Cavalli
Publikováno v:
Investigational New Drugs. 3:63-66
Epirubicin, a stereoisomer of doxorubicin with suggested lower potential for cardiotoxicity in experimental animal tumor systems, was studied in a disease-oriented phase II trial in patients with advanced colorectal cancer. The drug was given as a di
Autor:
Eduard E. Holdener, Pierre Alberto, Victor Hofmann, P. Siegenthaler, Reto Abele, Susanna Kaplan, Ryssel Hj, Diethelm Hartmann, Franco Cavalli
Publikováno v:
Journal of Clinical Oncology. 1:750-754
Doxifluridine, a new fluoropyrimidine derivative, was tested in a cooperative phase II trial by the Swiss Group for Clinical Cancer Research in advanced measurable colorectal cancer. The drug was given in a five consecutive day schedule by a bolus in