Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Eduard Daura"'
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
Cystatin B (CSTB) is a cysteine cathepsin inhibitor whose biallelic loss-of-function mutations in human result in defects in brain development and in neurodegeneration. The physiological function of CSTB is largely unknown, and the mechanisms underly
Externí odkaz:
https://doaj.org/article/bb9e8c239ab84227a67f4b49aa9c7288
Autor:
Eduard Daura, Saara Tegelberg, Masahito Yoshihara, Christopher Jackson, Francesca Simonetti, Katri Aksentjeff, Sini Ezer, Paula Hakala, Shintaro Katayama, Juha Kere, Anna-Elina Lehesjoki, Tarja Joensuu
Publikováno v:
Neurobiology of Disease, Vol 156, Iss , Pp 105418- (2021)
Cystatin B (CSTB) acts as an inhibitor of cysteine proteases of the cathepsin family and loss-of-function mutations result in human brain diseases with a genotype-phenotype correlation. In the most severe case, CSTB-deficiency disrupts brain developm
Externí odkaz:
https://doaj.org/article/e25ef9ea29f0476d9ed82d1d631b1cf3
Autor:
Anna-Elina Lehesjoki, Christopher B. Jackson, Saara Tegelberg, Katri Aksentjeff, Juha Kere, Masahito Yoshihara, Eduard Daura, Paula Hakala, Shintaro Katayama, Sini Ezer, Francesca Simonetti, Tarja Joensuu
Publikováno v:
Neurobiology of Disease, Vol 156, Iss, Pp 105418-(2021)
Cystatin B (CSTB) acts as an inhibitor of cysteine proteases of the cathepsin family and loss-of-function mutations result in human brain diseases with a genotype-phenotype correlation. In the most severe case, CSTB-deficiency disrupts brain developm
Autor:
Saara Tegelberg, Anna-Elina Lehesjoki, Katri Aksentjeff, Eduard Daura, Juha Kere, Sini Ezer, Christopher B. Jackson, Masahito Yoshihara, Francesca Simonetti, Paula Hakala, Shintaro Katayama, Tarja Joensuu
We establish cystatin B (CSTB) as a regulator of histone H3 tail clipping in murine neural progenitor cells (NPCs) and provide evidence suggesting that epigenetic dysregulation contributes to the early pathogenesis in brain disorders associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d3f3882dad3b1e59b4b978361dc700a9
https://doi.org/10.1101/2020.08.21.261180
https://doi.org/10.1101/2020.08.21.261180