Zobrazeno 1 - 10
of 67
pro vyhledávání: '"Eduard B Babiychuk"'
Autor:
Alexander P Atanassoff, Heidi Wolfmeier, Roman Schoenauer, Andrea Hostettler, Avi Ring, Annette Draeger, Eduard B Babiychuk
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89743 (2014)
Pathogenic bacteria secrete pore-forming toxins that permeabilize the plasma membrane of host cells. Nucleated cells possess protective mechanisms that repair toxin-damaged plasmalemma. Currently two putative repair scenarios are debated: either the
Externí odkaz:
https://doaj.org/article/8beed59bec4244f78bc9e0a34ea23a3c
Autor:
Eduard B Babiychuk, Alexander P Atanassoff, Katia Monastyrskaya, Christina Brandenberger, Daniel Studer, Catherine Allemann, Annette Draeger
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23706 (2011)
Ceramide is a key lipid mediator of cellular processes such as differentiation, proliferation, growth arrest and apoptosis. During apoptosis, ceramide is produced within the plasma membrane. Although recent data suggest that the generation of intrace
Externí odkaz:
https://doaj.org/article/40a691cd877a49669246d82f976f1014
Autor:
Judith Lang, Patrick Bohn, Hilal Bhat, Holger Jastrow, Bernd Walkenfort, Feyza Cansiz, Julian Fink, Michael Bauer, Dominik Olszewski, Ana Ramos-Nascimento, Vikas Duhan, Sarah-Kim Friedrich, Katrin Anne Becker, Adalbert Krawczyk, Michael J. Edwards, Andreas Burchert, Magdalena Huber, Justa Friebus-Kardash, Joachim R. Göthert, Cornelia Hardt, Hans Christian Probst, Fabian Schumacher, Karl Köhrer, Burkhard Kleuser, Eduard B. Babiychuk, Beate Sodeik, Jürgen Seibel, Urs F. Greber, Philipp A. Lang, Erich Gulbins, Karl S. Lang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Macrophages are critical in limiting replication of herpes simplex virus type 1 (HSV-1). Here the authors show how acid ceramidase and its enzymatic product sphingosine enable multivesicular bodies to function as an anti-viral mechanism.
Externí odkaz:
https://doaj.org/article/ce87beeac86246829e4b47c4ed971f39
Publikováno v:
Cells, Vol 11, Iss 1, p 166 (2022)
The increasing antibiotic resistance of bacterial pathogens fosters the development of alternative, non-antibiotic treatments. Antivirulence therapy, which is neither bacteriostatic nor bactericidal, acts by depriving bacterial pathogens of their vir
Externí odkaz:
https://doaj.org/article/1a6c0cf01d9f4eb68bc7fbae3a765c70
Autor:
Heidi Wolfmeier, Sarah C. Mansour, Leo T. Liu, Daniel Pletzer, Annette Draeger, Eduard B. Babiychuk, Robert E.W. Hancock
Publikováno v:
EBioMedicine, Vol 33, Iss , Pp 211-217 (2018)
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), typified by the pulse-field type USA300, is an emerging endemic pathogen that is spreading rapidly among healthy people. CA-MRSA causes skin and soft tissue infections, life-
Externí odkaz:
https://doaj.org/article/015e710ff6b84a8094608431c5de5ae3
Autor:
Heidi, Wolfmeier, Samuel J T, Wardell, Leo T, Liu, Reza, Falsafi, Annette, Draeger, Eduard B, Babiychuk, Daniel, Pletzer, Robert E W, Hancock
Publikováno v:
Frontiers in microbiology. 13
Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as
Autor:
Heidi Wolfmeier, Samuel J. T. Wardell, Leo T. Liu, Reza Falsafi, Annette Draeger, Eduard B. Babiychuk, Daniel Pletzer, Robert E. W. Hancock
Publikováno v:
Wolfmeier, Heidi; Wardell, Samuel J T; Liu, Leo T; Falsafi, Reza; Draeger, Annette; Babiychuk, Eduard B; Pletzer, Daniel; Hancock, Robert E W (2022). Targeting the Pseudomonas aeruginosa Virulence Factor Phospholipase C With Engineered Liposomes. Frontiers in Microbiology, 13, p. 867449. Frontiers 10.3389/fmicb.2022.867449
Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b46ff17e4347994c68522ba60178a913
Autor:
Eduard B. Babiychuk, Yu Larpin, Annette Draeger, Mircea-Ioan Iacovache, Victoriia S. Babiychuk, Hervé Besançon, Benoît Zuber, René Köffel
Publikováno v:
The FASEB Journal. 34:1665-1678
Bacterial infectious diseases can lead to death or to serious illnesses. These outcomes are partly the consequence of pore‐forming toxins, which are secreted by the pathogenic bacteria (eg, pneumolysin of Streptococcus pneumoniae). Pneumolysin bind
Publikováno v:
Toxins
Pore-forming toxins (PFTs) form multimeric trans-membrane pores in cell membranes that differ in pore channel diameter (PCD). Cellular resistance to large PFTs (>20 nm PCD) was shown to rely on Ca2+ influx activated membrane repair mechanisms. Small
Autor:
Parham Sendi, Dominik Schittny, Viktoriia S. Babiychuk, Yu Larpin, René Köffel, Eduard B. Babiychuk, Annette Draeger, Lara Brockhus, Lucy J. Hathaway, Hervé Besançon
Publikováno v:
Journal of Nanobiotechnology, Vol 19, Iss 1, Pp 1-15 (2021)
Journal of Nanobiotechnology
Besançon, Hervé; Babiychuk, Viktoriia; Larpin, Yu; Köffel, René; Schittny, Dominik; Brockhus, Lara; Hathaway, Lucy J.; Sendi, Parham; Draeger, Annette; Babiichuk, Eduard (2021). Tailored liposomal nanotraps for the treatment of Streptococcal infections. Journal of nanobiotechnology, 19(1), p. 46. BioMed Central 10.1186/s12951-021-00775-x
Journal of Nanobiotechnology
Besançon, Hervé; Babiychuk, Viktoriia; Larpin, Yu; Köffel, René; Schittny, Dominik; Brockhus, Lara; Hathaway, Lucy J.; Sendi, Parham; Draeger, Annette; Babiichuk, Eduard (2021). Tailored liposomal nanotraps for the treatment of Streptococcal infections. Journal of nanobiotechnology, 19(1), p. 46. BioMed Central 10.1186/s12951-021-00775-x
Background Streptococcal infections are associated with life-threatening pneumonia and sepsis. The rise in antibiotic resistance calls for novel approaches to treat bacterial diseases. Anti-virulence strategies promote a natural way of pathogen clear
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2aeb5557779461e243883cb8371dabbc
https://doi.org/10.21203/rs.3.rs-52770/v1
https://doi.org/10.21203/rs.3.rs-52770/v1