Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Eduard B, Babiychuk"'
Autor:
Heidi Wolfmeier, Samuel J. T. Wardell, Leo T. Liu, Reza Falsafi, Annette Draeger, Eduard B. Babiychuk, Daniel Pletzer, Robert E. W. Hancock
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as Streptococcus pneumoniae and Staphylococcus aur
Externí odkaz:
https://doaj.org/article/840210bfc16444c586864df92061739c
Autor:
Judith Lang, Patrick Bohn, Hilal Bhat, Holger Jastrow, Bernd Walkenfort, Feyza Cansiz, Julian Fink, Michael Bauer, Dominik Olszewski, Ana Ramos-Nascimento, Vikas Duhan, Sarah-Kim Friedrich, Katrin Anne Becker, Adalbert Krawczyk, Michael J. Edwards, Andreas Burchert, Magdalena Huber, Justa Friebus-Kardash, Joachim R. Göthert, Cornelia Hardt, Hans Christian Probst, Fabian Schumacher, Karl Köhrer, Burkhard Kleuser, Eduard B. Babiychuk, Beate Sodeik, Jürgen Seibel, Urs F. Greber, Philipp A. Lang, Erich Gulbins, Karl S. Lang
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Macrophages are critical in limiting replication of herpes simplex virus type 1 (HSV-1). Here the authors show how acid ceramidase and its enzymatic product sphingosine enable multivesicular bodies to function as an anti-viral mechanism.
Externí odkaz:
https://doaj.org/article/ce87beeac86246829e4b47c4ed971f39
Publikováno v:
Cells, Vol 11, Iss 1, p 166 (2022)
The increasing antibiotic resistance of bacterial pathogens fosters the development of alternative, non-antibiotic treatments. Antivirulence therapy, which is neither bacteriostatic nor bactericidal, acts by depriving bacterial pathogens of their vir
Externí odkaz:
https://doaj.org/article/1a6c0cf01d9f4eb68bc7fbae3a765c70
Autor:
Heidi Wolfmeier, Sarah C. Mansour, Leo T. Liu, Daniel Pletzer, Annette Draeger, Eduard B. Babiychuk, Robert E.W. Hancock
Publikováno v:
EBioMedicine, Vol 33, Iss , Pp 211-217 (2018)
Community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA), typified by the pulse-field type USA300, is an emerging endemic pathogen that is spreading rapidly among healthy people. CA-MRSA causes skin and soft tissue infections, life-
Externí odkaz:
https://doaj.org/article/015e710ff6b84a8094608431c5de5ae3
Publikováno v:
Toxins, Vol 13, Iss 2, p 126 (2021)
Pore-forming toxins (PFTs) form multimeric trans-membrane pores in cell membranes that differ in pore channel diameter (PCD). Cellular resistance to large PFTs (>20 nm PCD) was shown to rely on Ca2+ influx activated membrane repair mechanisms. Small
Externí odkaz:
https://doaj.org/article/5850a966b2c24dbba6cd675c17b075bb
Autor:
René Köffel, Heidi Wolfmeier, Yu Larpin, Hervé Besançon, Roman Schoenauer, Viktoria S. Babiychuk, Patrick Drücker, Thomas Pabst, Timothy J. Mitchell, Eduard B. Babiychuk, Annette Draeger
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Bacterial infectious diseases are a leading cause of death. Pore-forming toxins (PFTs) are important virulence factors of Gram-positive pathogens, which disrupt the plasma membrane of host cells and can lead to cell death. Yet, host defense and cell
Externí odkaz:
https://doaj.org/article/ab204a27906c4eb7b16198098641d220
Autor:
Heidi, Wolfmeier, Samuel J T, Wardell, Leo T, Liu, Reza, Falsafi, Annette, Draeger, Eduard B, Babiychuk, Daniel, Pletzer, Robert E W, Hancock
Publikováno v:
Frontiers in microbiology. 13
Engineered liposomes composed of the naturally occurring lipids sphingomyelin (Sm) and cholesterol (Ch) have been demonstrated to efficiently neutralize toxins secreted by Gram-positive bacteria such as
Autor:
Eduard B. Babiychuk, Yu Larpin, Annette Draeger, Mircea-Ioan Iacovache, Victoriia S. Babiychuk, Hervé Besançon, Benoît Zuber, René Köffel
Publikováno v:
The FASEB Journal. 34:1665-1678
Bacterial infectious diseases can lead to death or to serious illnesses. These outcomes are partly the consequence of pore‐forming toxins, which are secreted by the pathogenic bacteria (eg, pneumolysin of Streptococcus pneumoniae). Pneumolysin bind
Autor:
Alexander P Atanassoff, Heidi Wolfmeier, Roman Schoenauer, Andrea Hostettler, Avi Ring, Annette Draeger, Eduard B Babiychuk
Publikováno v:
PLoS ONE, Vol 9, Iss 2, p e89743 (2014)
Pathogenic bacteria secrete pore-forming toxins that permeabilize the plasma membrane of host cells. Nucleated cells possess protective mechanisms that repair toxin-damaged plasmalemma. Currently two putative repair scenarios are debated: either the
Externí odkaz:
https://doaj.org/article/8beed59bec4244f78bc9e0a34ea23a3c
Publikováno v:
Toxins
Pore-forming toxins (PFTs) form multimeric trans-membrane pores in cell membranes that differ in pore channel diameter (PCD). Cellular resistance to large PFTs (>20 nm PCD) was shown to rely on Ca2+ influx activated membrane repair mechanisms. Small