Zobrazeno 1 - 10
of 156
pro vyhledávání: '"Eduard A. Struys"'
Autor:
Rimke R. de Kroon, Nina M. Frerichs, Eduard A. Struys, Nanne K. de Boer, Tim G. J. de Meij, Hendrik J. Niemarkt
Publikováno v:
Sensors, Vol 24, Iss 10, p 3162 (2024)
Early diagnosis and treatment of late-onset sepsis (LOS) is crucial for survival, but challenging. Intestinal microbiota and metabolome alterations precede the clinical onset of LOS, and the preterm gut is considered an important source of bacterial
Externí odkaz:
https://doaj.org/article/2c21b777683e4d098368ff6cb2d8c7d4
Autor:
Eva Vermeer, Jasmijn Z. Jagt, Trenton K. Stewart, James A. Covington, Eduard A. Struys, Robert de Jonge, Nanne K. H. de Boer, Tim G. J. de Meij
Publikováno v:
Sensors, Vol 24, Iss 9, p 2727 (2024)
The gut microbiota and its related metabolites differ between inflammatory bowel disease (IBD) patients and healthy controls. In this study, we compared faecal volatile organic compound (VOC) patterns of paediatric IBD patients and controls with gast
Externí odkaz:
https://doaj.org/article/ee37dd27c7714c0d9c448e23e2675473
Autor:
Ittai B. Muller, Marry Lin, Robert de Jonge, Nico Will, Baltasar López-Navarro, Conny van der Laken, Eduard A. Struys, Cees B. M. Oudejans, Yehuda G. Assaraf, Jacqueline Cloos, Amaya Puig-Kröger, Gerrit Jansen
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9641 (2023)
Macrophages constitute important immune cell targets of the antifolate methotrexate (MTX) in autoimmune diseases, including rheumatoid arthritis. Regulation of folate/MTX metabolism remains poorly understood upon pro-inflammatory (M1-type/GM-CSF-pola
Externí odkaz:
https://doaj.org/article/58bcdab9dd664438b883f37eac80b355
Autor:
Francisca A. deLeeuw, Carel F.W. Peeters, Maartje I. Kester, Amy C. Harms, Eduard A. Struys, Thomas Hankemeier, Herman W.T. vanVlijmen, Sven J. van derLee, Cornelia M. vanDuijn, Philip Scheltens, Ayşe Demirkan, Mark A. van deWiel, Wiesje M. van derFlier, Charlotte E. Teunissen
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 8, Iss 1, Pp 196-207 (2017)
Abstract Introduction Identification of blood‐based metabolic changes might provide early and easy‐to‐obtain biomarkers. Methods We included 127 Alzheimer's disease (AD) patients and 121 control subjects with cerebrospinal fluid biomarker‐con
Externí odkaz:
https://doaj.org/article/46ce31ad3a8644bcb02482c9208ce810
Publikováno v:
Arquivos de Neuro-Psiquiatria, Vol 66, Iss 2a, Pp 288-289 (2008)
Externí odkaz:
https://doaj.org/article/52fc10328f17456b95aa74c0dbc505dc
Autor:
Jansen, Ittai B. Muller, Marry Lin, Robert Jonge, Nico Will, Baltasar López-Navarro, Conny van der Laken, Eduard A. Struys, Cees B. M. Oudejans, Yehuda G. Assaraf, Jacqueline Cloos, Amaya Puig-Kröger, Gerrit
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 11; Pages: 9641
Macrophages constitute important immune cell targets of the antifolate methotrexate (MTX) in autoimmune diseases, including rheumatoid arthritis. Regulation of folate/MTX metabolism remains poorly understood upon pro-inflammatory (M1-type/GM-CSF-pola
Autor:
Tim G. J. de Meij, Erwin E. W. Jansen, Johan Van Limbergen, Ibrahim Ayada, Marc A. Benninga, Abdellatif Bakkali, Nanne K. H. de Boer, Jürgen Claesen, Eduard A. Struys, Jasmijn Z. Jagt
Publikováno v:
Inflammatory bowel diseases, 28(5), 755-763. John Wiley and Sons Inc.
Jagt, J Z, Struys, E A, Ayada, I, Bakkali, A, Jansen, E E W, Claesen, J R, van Limbergen, J E, Benninga, M A, de Boer, N K H & de Meij, T G J 2022, ' Fecal Amino Acid Analysis in Newly Diagnosed Pediatric Inflammatory Bowel Disease : A Multicenter Case-Control Study ', Inflammatory Bowel Diseases, vol. 28, no. 5, pp. 755-763 . https://doi.org/10.1093/ibd/izab256
Inflammatory Bowel Diseases, 28(5), 755-763. John Wiley and Sons Inc.
Jagt, J Z, Struys, E A, Ayada, I, Bakkali, A, Jansen, E E W, Claesen, J R, van Limbergen, J E, Benninga, M A, de Boer, N K H & de Meij, T G J 2022, ' Fecal Amino Acid Analysis in Newly Diagnosed Pediatric Inflammatory Bowel Disease : A Multicenter Case-Control Study ', Inflammatory Bowel Diseases, vol. 28, no. 5, pp. 755-763 . https://doi.org/10.1093/ibd/izab256
Inflammatory Bowel Diseases, 28(5), 755-763. John Wiley and Sons Inc.
Background Fecal metabolomic profiles differ between pediatric inflammatory bowel disease (IBD) patients and controls and may provide new insights in the pathophysiology of IBD. The role of amino acids, however, is not fully elucidated. We aimed to a
Autor:
Renske CF Hebing, Marry Lin, Maja Bulatovic Calasan, Ittai B Muller, Sohaila Mahmoud, Sandra Heil, Eduard A Struys, Bart JF van den Bemt, Jos WR Twisk, Willem Lems, Michael T Nurmohamed, Gerrit Jansen, Robert de Jonge
Publikováno v:
Hebing, R C, Lin, M, Bulatovic Calasan, M, Muller, I B, Mahmoud, S, Heil, S, Struys, E A, van den Bemt, B J, Twisk, J W, Lems, W, Nurmohamed, M T, Jansen, G & de Jonge, R 2022, ' Pharmacokinetics of oral and subcutaneous methotrexate in red and white blood cells in patients with early rheumatoid arthritis : the methotrexate monitoring trial ', Annals of the Rheumatic Diseases . https://doi.org/10.1136/ard-2022-223398
Annals of the Rheumatic Diseases. BMJ Publishing Group
Annals of the Rheumatic Diseases, 82(4):223398, 460-467. BMJ Publishing Group
Annals of the Rheumatic Diseases. BMJ Publishing Group
Annals of the Rheumatic Diseases, 82(4):223398, 460-467. BMJ Publishing Group
ObjectiveTo investigate the pharmacokinetics of methotrexate polyglutamate (MTX-PG) accumulation in red blood cells (RBCs) and peripheral blood mononuclear cells (PBMCs) in patients with early rheumatoid arthritis (RA) after oral and subcutaneous MTX
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4fed2cdd72bcbd6fd00e20f59d9939f
https://research.vumc.nl/en/publications/6f32a105-afa2-4d5b-b018-d70e76db34a3
https://research.vumc.nl/en/publications/6f32a105-afa2-4d5b-b018-d70e76db34a3
Autor:
Sofie Bosch, Animesh Acharjee, Mohammed Nabil Quraishi, Irene V Bijnsdorp, Patricia Rojas, Abdellatif Bakkali, Erwin EW Jansen, Pieter Stokkers, Johan Kuijvenhoven, Thang V Pham, Andrew D Beggs, Connie R Jimenez, Eduard A Struys, Georgios V Gkoutos, Tim GJ de Meij, Nanne KH de Boer
Publikováno v:
Gut Microbes, 14(1). Landes Bioscience
Bosch, S, Acharjee, A, Quraishi, M N, Bijnsdorp, I V, Rojas, P, Bakkali, A, Jansen, E E, Stokkers, P, Kuijvenhoven, J, Pham, T V, Beggs, A D, Jimenez, C R, Struys, E A, Gkoutos, G V, de Meij, T G & de Boer, N K 2022, ' Integration of stool microbiota, proteome and amino acid profiles to discriminate patients with adenomas and colorectal cancer ', Gut Microbes, vol. 14, no. 1, pp. 2139979 . https://doi.org/10.1080/19490976.2022.2139979
Bosch, S, Acharjee, A, Quraishi, M N, Bijnsdorp, I V, Rojas, P, Bakkali, A, Jansen, E E, Stokkers, P, Kuijvenhoven, J, Pham, T V, Beggs, A D, Jimenez, C R, Struys, E A, Gkoutos, G V, de Meij, T G & de Boer, N K 2022, ' Integration of stool microbiota, proteome and amino acid profiles to discriminate patients with adenomas and colorectal cancer ', Gut Microbes, vol. 14, no. 1, pp. 2139979 . https://doi.org/10.1080/19490976.2022.2139979
BACKGROUND: Screening for colorectal cancer (CRC) reduces its mortality but has limited sensitivity and specificity. Aims We aimed to explore potential biomarker panels for CRC and adenoma detection and to gain insight into the interaction between gu
Autor:
Jiddeke M. van de Kamp, Arend Bökenkamp, Desiree E. C. Smith, Mirjam M. C. Wamelink, Erwin E. W. Jansen, Eduard A. Struys, Quinten Waisfisz, Marieke Verkleij, Michaela F. Hartmann, Rong Wang, Stefan A. Wudy, Chiara Paganini, Antonio Rossi, Martijn J. J. Finken
Publikováno v:
van de Kamp, J M, Bökenkamp, A, Smith, D E C, Wamelink, M M C, Jansen, E E W, Struys, E A, Waisfisz, Q, Verkleij, M, Hartmann, M F, Wang, R, Wudy, S A, Paganini, C, Rossi, A & Finken, M J J 2023, ' Biallelic variants in the SLC13A1 sulfate transporter gene cause hyposulfatemia with a mild spondylo-epi-metaphyseal dysplasia ', Clinical Genetics, vol. 103, no. 1, pp. 45-52 . https://doi.org/10.1111/cge.14239
Clinical Genetics, 103(1), 45-52. Wiley-Blackwell
Clinical Genetics, 103(1), 45-52. Wiley-Blackwell
Sulfate is the fourth most abundant anion in human plasma but is not measured in clinical practice and little is known about the consequences of sulfate deficiency. Nevertheless, sulfation plays an essential role in the modulation of numerous compoun